This is the initial presentation that Biosortia delivered on the Innovation Ecosystem Forum. We had some challenges with the functionality of this session. We were unable to provide the verbal interactive Q&A. Biosortia was kind enough to present a second time so we could provide them with the benefits derived from that verbal interaction. There are also additional insights in this video.
Industrial Scale Microbiome Mining: Collaborative Innovations in Materials, Defense, and Energy.
Collaborative Innovations in Materials, Defense, and Energy.
Unveiling the Microbial Dark Matter: Industrial Scale Microbiome Mining:
Problem: Despite only harnessing 1% of microbial diversity and their remarkable chemistry, science
and industry have already unlocked significant benefits, generating a colossal $23 trillion annual global economic impact (Bard). However, we've barely scratched the surface of this treasure trove. Millions of uncultivated microbial species represent a powerhouse of potential, waiting to be explored for direct applications to revolutionize existing industries. While established technologies, despite decades of research and trillion-dollar investments, stagnate (example: dwindling new (NME) FDA-approved drugs), microbes hold immense promise for breakthroughs in virtually every sector. It's time to expand focus, unlock the dormant potential of uncultivable microbes, and unleash a new era of innovation.
Opportunity: Millions of microbial unknowns - small molecules, enzymes, lipids, even entire species
- lie concealed within the vast "dark matter" of microbiology. While some microbes pose potent threats to humanity, the vast majority hold an untapped potential for positive breakthroughs. New and improved technologies are emerging that can bypass traditional culturing methods and directly access this hidden treasure trove. These tools, alongside enhanced AI versions of existing indirect methods, open the door to a wealth of discoveries. Harnessing all available approaches is crucial to uncover both the promising opportunities and the potential threats veiled within the microbial dark matter.
Biosortia: Unlocking the Microbiome's Secrets without Culturing: Biosortia offers a revolutionary
approach to microbiome exploration, bypassing traditional culturing methods. This "culture-independent breakthrough" allows us to directly harness the power of naturally occurring microbiomes, on a massive scale, without harming the environment. This opens a doorway to a hidden world of molecules and AI enhanced data with immense potential for scientific and industrial breakthroughs.
Microbial marvel: billions of years in the making: Imagine an entire world teeming with tiny
scientists, tinkering away for billions of years. That's essentially what the microbial world is: a vast
ecosystem where microscopic beings have honed their metabolic skills to perfection. These "nature's
biocatalyst powerhouses" have evolved incredibly diverse pathways, allowing them to utilize unique
resources and produce a staggering array of complex molecules. In short, they're nature's secret
weapon, impacting everything from our health, food, the air we breathe, to the soil we walk on.
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