I turned to genetic data mainly because of all the strange reactions I was having to supposedly healthy supplements. I had high homocysteine levels on tests and a Functional Medicine MD gave me methyl folate and B12. Folate caused incredible anxiety and B12 caused rage. The list continues. Quercetin causing a feeling of adrenaline, Glutamine creating agitation, ALA causing massive flare ups of inflammation and neurological symptoms, SAMe causing panic. I needed answers because I was running into dead ends. And the things I've read about in so many articles about CBS and COMT, two things I'm homozygous for, none of the things discussed in those articles discussed were discussed here. Rising levels of ammonia. Sulfite level increases shown on urine test strips. I did retreat to diet but eating things high in B12 like beef liver or sardines creates rage symptoms. I'll let you know if the second wave of lyme treatment I'm under-going will have an impact on any of this. I wonder if the genetic expression I'm experiencing isn't from my genome at all, but of the bugs inhabiting my body.
@BeHappyBeHappybe1111
Жыл бұрын
Ur case is so much like mine it’s unreal - let’s crack this !! There has to be a way to hack this
@LinnRivers
11 ай бұрын
Have you found anything to shift since you've last posted this comment? Also, feel there has to be something more approachable to getting this under control.
@MrBrianDuga
11 ай бұрын
@@LinnRivers this one is still a little tough but I do find that if I'm not going to be under stress, using methyl donors may not be so bad on that day. But I do occasionally get blind-sided by a rage-ful reaction when using them. The biggest issue is I don't realize it until it's too late. In all cases, even when pulsing (taking like a weekend off), easing into the dosage is key for me. I can't just hit the ground running with the previous week's dose and expect to be all parasympathetic. My current learning path is on the Metabolic Typing Diet (William Wolcott's book) as a part of training to become an FDN-P. Interesting things about Sympathetic Dominant types where certain foods can drive one to irritability. Strangely, high purine meats like liver - which also invoke an irritability reaction in me - similar correlation may be they are high in methyl donors.
@beccalynne31
2 жыл бұрын
What if someone has gut issues and they have can't absorb nutrients through food. Fut2, IBS, gastritis ect
@BeHappyBeHappybe1111
Жыл бұрын
What advice for cbs down regulators with high homocysteine??? All advice is for upregulation only so frustrating!😅
@fastolov982
4 жыл бұрын
Thank you so much for this! Could you explain a little more how does the cbs mutation affect fertility ?
@FXMedicine
4 жыл бұрын
We don't currently have any specific resources to share with you in regards to CBS and fertility. We do have the following article that discusses some of the key genetic pathways to consider in fertility: www.fxmedicine.com.au/blog-post/fertility-management-and-nutrigenomics We can reach out in our network and see if there's someone with expertise on CBS and fertility - we'll add this to our podcast list. Thanks for the feedback.
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