All references below. Inhalant misuse is well-documented to cause permanent damage to the body. The neurological damage can be acute, and continued misuse will progress to multi-organ damage. Sudden cardiac death is also known to happen with this misuse, along with a variety of additional problems.
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Toluene Toxic Leukoencephalopathy Image case courtesy of Dr Chee Kok Yoon, Radiopaedia.org, rID: 17082
These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
References:
Syndromes of toluene sniffing in adults. Ann Intern Med. 1981;94:758-762.
Glue-sniffing and distal renal tubular acidosis: sticking to the facts. pubmed.ncbi.nl...
Laboratory approach for diagnosis of toluene-based inhalant abuse in a clinical setting.
www.ncbi.nlm.n...
Neurotoxicity of solvents in brain of glue abusers. pubmed.ncbi.nl...
Neural basis of inhalant abuse. pubmed.ncbi.nl...
A rare but serious case of toluene-induced sudden sniffing death. www.sciencedir...
Hydrocarbon toxicity: A review. www.tandfonlin...
Inhalant Misuse in children and adolescents. UpToDate. Accessed 28 Mar 2023.
Effect of benzene, toluene, xylene on the .. quality of exposed workers. pubmed.ncbi.nl...
Effects of pH on Potassium: New Explanations for Old Observations. www.ncbi.nlm.n...
THE EFFECT IN HUMANS OF EXTRACELLULAR pH CHANGE ON THE RELATIONSHIP BETWEEN SERUM POTASSIUM CONCENTRATION AND INTRACELLULAR POTASSIUM. www.ncbi.nlm.n...
MR Imaging of "Spray Heads": Toluene Abuse via Aerosol Paint Inhalation www.ncbi.nlm.n...
Review of toluene action: clinical evidence, animal studies and molecular targets. www.ncbi.nlm.n...
On the mechanism of rhabdomyolysis in potassium depletion. www.ncbi.nlm.n...
The Effects of Toluene on the Central Nervous System academic.oup.c...
Goldfrank’s Toxicologic Emergencies. 11th ed.
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