the only one there that makes biochemistry (and other topics too) simple and doable! thank you so much for everything
@stronger3381
4 жыл бұрын
ninja nerd does his thing too. check him out :)
@DaktuurAmarAKA
2 жыл бұрын
You can't compare him with Dirty med , Dirty med is a bang and a beast
@medimachete
Жыл бұрын
@@DaktuurAmarAKA They just are for different aspects. For in depth, Ninja Nerd is amazing. For quick review for testing, DirtyMed is the Goat.
@luisg.ortiztorres2516
3 жыл бұрын
international mnemonic for NADH:NAD+.. too much *H*eineken leads to too much NAD*H*...
@howiegwok3703
7 ай бұрын
Mnemonic for Fomepizole: think it as Foam-epizole, which can turn the beer to a lot of foam and less liquid (dehydro).
@jainilshah9367
4 жыл бұрын
Why can't the body get rid of the NADH via the Electron Transport Chain?
@Gasmanz
3 жыл бұрын
I’m not entirely certain, but I don’t think the liver has an adequate amount of oxygen to use for the etc to work at the level necessary to get rid of the excess nadh
@vedanshchaudhari2253
2 жыл бұрын
Well to some extent NADH does go to ETC, but it isn't enough in cases of alcohol overdose
@aishwaryadhawle992
4 жыл бұрын
Superb explaination.. 😍
@ellohappy
Ай бұрын
Fatty MiLK: NADH/NAD+ stimulated pathways increase Fatty Acids, G3P, Triglycerides, and Malate, Lactate acids, and Ketoacids :)
@Dr.Microglia
10 ай бұрын
Thank you for making biochemistry easier ☺️.
@macfrichtel1
5 жыл бұрын
Is acetaldehyde dehydrogenase similar to Formaldehyde
@KingOfAllLlamas
2 жыл бұрын
@slicky villy No need to be a dick about it. Just highlights your intellectual insecurity.
@sneezyzneezy
5 жыл бұрын
GOAT
@ericmurithi8481
3 жыл бұрын
If the NADH levels are high wouldn't that favour gluconeogenesis?
@ASAINsensation
2 жыл бұрын
yea I'm confused here as well; if TCA is decreased due to low oxaloacetate levels and there is a buildup of acetyl-CoA, wouldn't that promote gluconeogenesis because acetyl-CoA is a positive regulator of pyruvate carboxylase?
@watvervlend1299
2 жыл бұрын
@@ASAINsensation Same :') can someone explain ?
@vedanshchaudhari2253
2 жыл бұрын
@@ASAINsensation Acetyle-CoA is indeed positive regulator of pyruvate carboxylase that coverts pyruvate into oxaloacetate. But here's the catch. In 8:09 minutes into this video he explains that pyruvate is also being used to compensate increased NADH by converting it into lactate. So there is not enough pyruvate left to convert into oxaloacetate so that it can participate in gluconeogenesis.
@rosemarymbonika8945
28 күн бұрын
High yield = Dirty medicine
@mohamedaboelfetouh93
3 ай бұрын
omg the way you explain everything smoothly!!!
@deekeyolmo564
5 жыл бұрын
Love you
@thineswarymanogaran5472
5 жыл бұрын
Thank you. Your video is very helpful. :)
@AsmaKhan-gz1by
4 жыл бұрын
Well-done
@livefitnesskh3408
2 жыл бұрын
I can’t see any health benefits from alcohol but why people like to drink it 🥴
@camilapayan712
Жыл бұрын
Question. In a past video you said Acetyl-CoA cannot be shunted from mitochondria to make ketones, which is why citrate is shuttled out... In this video you say Acetyl-CoA is used directly to make ketones. Can you explain the discrepancy please.
@saraa.5468
7 ай бұрын
Thank u so much for this wonderful explanation 😍
@ahnaf_akif_mbbs_bd_ksa
11 ай бұрын
the way you just broke down the metabolic pathways is just too beneficial to explain !!!! May you be rewarded ,sir
@alexboyemuller3898
3 жыл бұрын
witch level of education is this intended for?
@rosyreverie
3 жыл бұрын
This is for medical students studying for board exams, but I’m sure it’s helpful in other medial professions as well.
@alexboyemuller3898
3 жыл бұрын
@@rosyreverie thank you! I was wondering cuz it seemed just slightly above the level I'm on, but I'm also only in my 11th year of education, and half the issue is probably that English isn't my first language. It's very impressive how this is actually understandable to me (a 17 year old) even if it's a bit tough
@alexboyemuller3898
3 жыл бұрын
I'm not sure many 17 year olds would understand it though, I'm very much just a massive nerd
@mamdoohal-nassirat1627
2 жыл бұрын
@@alexboyemuller3898 bruh
@mamdoohal-nassirat1627
2 жыл бұрын
I understood this in my mom's womb.. I 1 upped you bro.. sorry
@ЄвгенійКоцур-ф1б
Жыл бұрын
Alse hyperuricemia can occur, uric acid competes with lactate and its elimination may be slowed down
@graciephil
4 жыл бұрын
AMAZING!!
@niceidea7454
3 жыл бұрын
❤️
@karentaylor8080
3 ай бұрын
Thanks very much
@jax40001
Жыл бұрын
Alcoholics have small NAD+s
@ЕленаХабдилан
3 жыл бұрын
I loved it
@padmajahawaldar4319
7 ай бұрын
❤
@MundoGamesDo
3 ай бұрын
THAAAAAAAAANKS
@AwaabHamed
9 ай бұрын
I love you
@noora.com322
Жыл бұрын
So helpful thanks
@funktionellemedizin6045
2 жыл бұрын
Thank you!!! Great Help!
@1412Z
Жыл бұрын
Thank you!
@دكتور2017الجامعةالاردنية
2 жыл бұрын
What happens to glycogenolysis ?
@vedanshchaudhari2253
2 жыл бұрын
Glycogenolysis will be promoted. As vlycogen breakdow:ns it does not necessarily becomes glucose. It can take alternate route and go on to form pyruvate, which as explained in this video at 8:09 can be converted into lactate
@sweetmishoo190
2 жыл бұрын
Ohhh thank you
@skarpengland
5 жыл бұрын
alcohol being metabolised in first order kinetic, would give the term "Chug chug chug" a whole new level of meaning
@NeuroPulse
Жыл бұрын
It sounds like you're talking to children.
@crafteezbyFami
2 жыл бұрын
It doesn't go with First aid
@sophiesheu
4 жыл бұрын
Something does not make sense here - if alcohol decreases gluconeogenesis and increases ketosis, would that make it a good thing to have during fasting for the sake of weight/fat loss? Since the whole idea of the keto diet is to deplete glucose and forces your body into a keto state so it burns stored fat. I am talking about pure alcohol here like vodka, not beer or wine.
@vide0gameCaster
4 жыл бұрын
The fact that it decresease Glucogenesis, it's because you have a high excess of NADH and a low ammount of NAD+. The high ammount of NADH will lead your body to synthesis all your nutrients into fatty acid... even Fruits, Vegetables and Cereals. So even healthy nutrients will be stored in your fat. The role of the NAD+ is to be able to increase your gluconeogenesis so you can transform your sugar into glycogene. Glycogene is needed to allow your cells to work. A low ammount of Glycogene means that your cells will go lazy and their membrane will grow larger because of the synthesis of fatty acid. And voila, you created a situation one can be at risk of gaining weight. Sorry if it's not 100% clear, english is not my first language.
@riyajha788
2 жыл бұрын
As gluconeogenesis is not working you’re already at risk of hypoglycaemia, so glycogen here becomes very important. Combine fasting state + alcohol= Severe hypoglycaemia, may even get seizures!
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