What is the main cause of Ankylosing spondylitis?
Ankylosing spondylitis - Symptoms & causes - Mayo Clinic
Ankylosing spondylitis has no known cause, though genetic factors seem to be involved. In particular, people with a gene called HLA-B27 are at a greatly increased risk of developing ankylosing spondylitis. However, only some people with the gene develop the condition.
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