I appreciate the info.. thank you for sharing. The product price is ridiculous... when wheat germ and natto are cheap and more sustainable in regards to a lifestyle change.
@LongevityAndLifestyle
11 ай бұрын
@gaston. Thanks for your comment - yes it's quite pricey! Glad you have an alternative and thanks for watching!
@sambo7734
Жыл бұрын
I'm confused by this. Apparently a balanced diet provides you with 10-20mg of spermidine per day. Why is a 1mg supplement of any value?
@4tun8nanette
11 ай бұрын
I think later she mentioned 8mg as a dose used in a study.
@MarieLamour-cv1jc
4 ай бұрын
Try it and see if it works. If it does not, carry on.
@robscasey
Жыл бұрын
There’s people out there trying to debunk spermadine. It’s hard to know what to think
@Sharperthanu1
3 ай бұрын
If you dont want wrinkles and cataracts and skin cancer keep your face and neck and as much of your body as possible out of the sun because sun exposure causes wrinkles,cataracts and skin cancer.Sun exposure may also damage your immune system.However you should never rely on sunscreen and sun glasses to block out all of the suns' rays because no sunscreen or sunglasses block out all of the suns' rays.Instead you should wear good hats: Opaque plastic sun visors or leather or vinyl cowboy hats and only wear them outside between noon and two P.M. when the sun is directly above and dont look up into the sun. About taking care of your heart: People shouldn't eat anymore than ten grams of saturated fat and or trans fat per day or they are at an increased risk of having a heart attack.I found that out from famous heart doctor Dr. Dean Ornish
@sncnutrition7118
Жыл бұрын
Best time of day or night to take Spermidine?
@rredding
Жыл бұрын
If you allow me, another question. I found medical literature, that relates cancer cells to Spermidine. It supports growth, and in that way should be beneficial to tumor cells. Are you familiar with this hypothesis and can you reflect on it? Thanks!
@reformedknight7506
5 ай бұрын
Spermidine possesses a positive charge at the physiological pH that enables its interaction with oppositely charged DNA and RNA (Madeo et al., 2018a). Dietary intake of spermidine reduces the risk of neurodegeneration, metabolic diseases, heart ailments, and cancer. Furthermore, spermidine-induced autophagy slows the rate of cognitive decline due to its ability to clear amyloid-beta plaques in the brain (Madeo et al., 2018b). Spermidine supplementation also enhances mitochondrial metabolism, and translational activity. The anticancer properties of spermidine are of particular interest as it is known to reduce the cancer-related mortality in humans (Pietrocola et al., 2019). The association between tumorigenesis and spermidine is determined by the regulation of polyamine metabolism, surveillance of immune system, apoptosis, and autophagy (Nampoothiri et al., 2023). Higher uptake of polyamines is known to suppress the tumor progression. Spermidine exhibits cell-autonomous effects on cancer cells, in addition to impacting their discourse with the immune effectors that result in expediting the identification of tumor-associated antigens and eventually cancer cell death (Fan et al., 2020). Spermidine-mediated autophagy inhibits activation of apoptosis in cancer cells (Madeo et al., 2019) and is associated with tissue development and cell differentiation (Ni and Liu, 2021).
@rredding
Жыл бұрын
Very very informative, thank you! I have a question.. Two forms are sold: Spermidine, a liquid produced from a natural source (wheat) and Spermidine.3HCl, a white powder, produced by chemical industry (e.g. in China). It is my assumption that all higher dosed capsules are the 3HCl form. I don't understand the remark about the difference between the "natural" and the "artificial" molecules, the left hand and the right hand. Spermidine is s fully rotational, simple molecule and there is no chirality, there is no left or right hand orientation, or am I wrong? I really hope you'll read and reply! 🙏🏻
@4tun8nanette
11 ай бұрын
Really great question. Sadly, still no answer.
@rredding
11 ай бұрын
@@4tun8nanettemmm yes.. I honestly don't expect a useful reply from the makers of this video
@4tun8nanette
8 ай бұрын
I came back to see if there was an answer. Sadly no reply.
@alanv5704
Жыл бұрын
Is there a difference In spermidine and spermidine trihydrochloride?
@rredding
Жыл бұрын
Hi Alan, that was exactly my question! This is what I wanted to ask: Two forms are sold: Spermidine, a liquid produced from a natural source (wheat) and Spermidine.3HCl, a white powder, produced by chemical industry (e.g. in China). It is my assumption that all higher dosed capsules are the 3HCl form. Do you have any information about the preferred form? Is there a difference, besides a possible contamination in the 3HCl form? I really hope you'll read and reply! 🙏🏻
@4tun8nanette
11 ай бұрын
@@rredding Please, who makes or sells the liquid Spermadine, if you know?
@rredding
11 ай бұрын
@@4tun8nanette sorry, I have no knowledge about that..
@ginnydoane4570
7 ай бұрын
Dr Greger talks about this in his book How Not to Age. It all science based. Never recommends supplementing.
@pepa1420
10 ай бұрын
Where do I get it ?
@radic888
7 ай бұрын
Does she mention the food sources?
@GraceDollesin
24 күн бұрын
Natto ! Eat Natto , it has 8.2 mg of Spermidine per 1 ounce. Dry pig pancreas 9.2 mg. Per ounce, mushrooms 9.2 mg. Per one ounce, tempeh 9.2 mg. Per once. Wheat germ, mangoes, broccoli. I eat Natto five times a day. I put 1/2 tsp. Of dried shitaki in my Natto, one ounce of tofu, a pinch of dried shogul, few flakes of seaweed, and I make a soup out it. It taste good. Just make sure to cool down the soup before incorporating the Natto at the last stage of making. It does help you with my aging. My whole body skin and face feels like I took a bath with oil of Olay. I’m 58 years old. My two young daughters can’t believe how youthful is my overall skin. I also make my own wheat germ . I put one tbsp. Of wheat germ in a cup of water and I open one probiotics mix it. I leave it by my nightstand overnight and drink it first thing in the morning.
@lauralijames6316
11 ай бұрын
I want to get her ptoduct. Where can I get it? Can you kindly provide me the information please?
@LongevityAndLifestyle
11 ай бұрын
@lauralijames6316 - yes it's amazing! I take the powdered form in my smoothie each morning. You can get 10% off by using my discount code CLAUDIA10 at checkout - oxfordhealthspan.com/
@반디-z4b
6 ай бұрын
Korean Cheong-gug-jang has higher efficacy than nato.
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