Several methods are used for adjusting the isotonicity of pharmaceutical preparations.
It can be calculated from the colligative properties of drug solutions.
If solutions are injected or introduced in to nose or eyes, these are to be made isotonic in order to avoid hemolysis of RBC’s and to avoid pain and discomfort.
The amount of adjusting agents to be added is easy to determine by using the appropriate calculations based on colligative properties of solutions.
It helps to overcome the side effects caused from administering solutions which contain adjusting agents more or less than isotonic solutions.
#isotonicity #NaClEquivalentMethod #SodiumChlorideEquivalentmethod #tonicityAdjustment
Негізгі бет Calculations for sodium chloride equivalent method for adjusting tonicity
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