i plan to make an extended video on the CAR T cells to explain deeply the potential. stay tuned!
@SlamminGraham
10 ай бұрын
Maybe it's time to abandon the notion of a clinical trial for a specific drug, and rather do clinical trials for a specific *procedure* involving a customized drug for each patient (which hopefully can be synthesized rapidly) which can be administered within a reasonable time frame. I'm kinda sick of clinical trials always being the excuse why nothing effective ever happens. Personalized medicine promises so much more for us.
@sunday6371
10 ай бұрын
I am very grateful to Dr Abiola on KZitem for curing me permanently from hiv with his herbal medicine #drabiola 💛😊
@Big_brain_bio
10 ай бұрын
I absolutely love your videos. They are very informative and they generate ambition in a mind of a young science student. Keep posting such useful videos. Kudos. Love from India🇮🇳
@BakamonNO
10 ай бұрын
Love the video. But the sound effects and the sound of the video clips are set to high fam 😊
@ArticBlueFox96
10 ай бұрын
Incredible. Hopefully this leads to a new generation of cancer drugs far superior to current treatments.
@robertkelleyroth409
8 ай бұрын
Excellent video. Potential upgraded modality for anti tumor therapies. One of your best of 2023.
@GodfreyMann
10 ай бұрын
Sheekey, please explain how the *plethora* of different DNA mutations all give rise to the same phenotype of uncontrollable cell replication…it makes no sense. And why is it that the almost all cancer cells have damaged mitochondria? In light of this, surely it makes more sense that it’s mitochondrial dysfunction that causes cancer via excessive ROS that damages DNA, especially as the cell cycle (cell death) is mediated by mitochondria? The nuclear transfer experiments carried out by Prof Thomas Seyfried of Boston College seems to prove this beyond all doubt, no?
@MW2xX
10 ай бұрын
What if the plethora of DNA damage causes the mitochondrial dysfunction? This then leads ROS production and then more DNA damage. In this since the DNA damage is the driver of cancer where the mitochondrial dysfunction is a distinguishable phenotype to acknowledge. There could be cancers where it’s the other way around or they are inextricably linked together? There is DNA in the mitochondria too?
@rigaleb
10 ай бұрын
well, when energy metabolism doesn't work anymore, things go sideways. Of course mithocondria have the master switch. Micromanaging T cells ain't gonna solve all of it, we need to take care of our mithocondria, we are nothing without them.
@GodfreyMann
10 ай бұрын
@@MW2xX the mechanisms of mitochondrial dysfunction are well understood and nuclear DNA mutation has nothing to do with it.
@MW2xX
10 ай бұрын
@@GodfreyMann is it 100% that mitochondrial DNA is not damaged?
@GodfreyMann
10 ай бұрын
@@MW2xX in some cases mitochondrial dysfunction arises from mtDNA mutation, but that’s not what Sheeky was talking about - her assertion is that cancer is caused by nuclear DNA mutation.
@ogeoge6000
10 ай бұрын
I'd love to know your thoughts on Professor Thomas Seyfried's work on cancer.
@walidoulondon8107
10 ай бұрын
Can you do a video on sirt6 activator please 🙏
@alexz1104
10 ай бұрын
Another great video! I would love to see you do one on distributed/volunteer computing projects in medicine like World Community Grid or SiDock.
@deadwalking100
10 ай бұрын
Thank you! Interesting potential for sure. Indeed one of the many things I have learned through your many excellent video presentations; being the immense complexity of the human body, and challenges that such cancers present to modern science. Loved the emphasis using sound effects and support graphics, speaking of which.... Oddly the cancer cell swirl graphic with no sound invoked in me the batman (showing my age Adam west 1960s TV series) sound, when they cut between a scene.
@paulollerhead
10 ай бұрын
Fantastic work yet again, thanks
@BK-dy8jk
10 ай бұрын
I love your show, but I hate those short little musical inserts that are extremely loud and interruptive. Not fun for listening.
@robertkelleyroth409
10 ай бұрын
That Murray et al paper is exciting - just 6 edits to go after solid tumors.
@kingsize1182
10 ай бұрын
👍🔥💯
@lonelyelectron5283
10 ай бұрын
I think car t cells is more promising therapy for blood disease like leukimia or autoimmune, they proven to be effective againts few type of blood cancer like lymphoma but not for solid tumo,t cells known have hard time to infiltrate solid tumor and struggle in tumor micro enviroment
@sunday6371
10 ай бұрын
I am very grateful to Dr Abiola on KZitem for curing me permanently from hiv with his herbal medicine #drabiola 💛😊
@Enhancedgenetics
10 ай бұрын
Sounds dangerous man fooling around with nature will end badly... 🙄😐
@basedchad6035
10 ай бұрын
no risk no fun
@Enhancedgenetics
10 ай бұрын
@@basedchad6035 risk to do what destroy yourself we are already unintouched with nature ... 😐
@blkshk2466
10 ай бұрын
@@Enhancedgenetics I hope neither you or no one in your family is taking any prescribed medications or going to hospitals then, gangatron
@basedchad6035
10 ай бұрын
@@Enhancedgenetics itl Happen no matter what so idc what u type of people think anyway
@Enhancedgenetics
10 ай бұрын
@@basedchad6035 I know humans hate nature & think they can do better yes,😊👍
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