Molecular basis of cancer
Protooncogenes into oncogenes
a. point mutation
b. chromosomal translocation
c. insertion of promotor or enhancer
d. gene amplification
oncogenes produces mutated proteins that causes accelerated cell division and cell growth
antioncogenes or tumoor suppressor genes
Mechanism of p53 tumor suppressor gene
Mechanism of RB Tumor suppressor gene
Негізгі бет Carcinogenesis, Oncogenes, Tumor suppressor genes
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