Thank you for this video! I work in an Immunology Lab and am giving a presentation about coeliac disease to my team. This has given me a lot of help articulating it, so thank you 😊
@BenDabber
5 жыл бұрын
Playback speed at 1.5 is about right.
@ryanmichaelhaley
4 жыл бұрын
I like 1.25
@dr.noir27
2 жыл бұрын
i appreciate the time you spent on making these animations
@joc4709
2 жыл бұрын
Amazing. I'm a student dietitian and this was presented more clearly than a recent lecture.
@DamjanManevski
2 жыл бұрын
I'm a Nutrition and Biomedicine Master and wow, what an explanation! Really good job mate
@xxblackgeishaxx
2 жыл бұрын
Thank you so much. I am presenting Celiac Disease for a case study to the Colonel and pathologists in 2 weeks and this helped me better understand exactly what is happening in the lining of the small intestines on a microscopic level.
@aliceeleonor2911
2 жыл бұрын
Awesome video! The pathophysiology is explained on point. Thanks!
@howtomedicate
5 жыл бұрын
Seriously, amazing videos. I am a 6th year Medical Student and this videos still help me! You even inspired me to make a channel on my own! I make YT videos on medical topics. And today I posted a video about celiac disease as well. Thanks for all the knowledge bombs, and thanks for the inspiration. Keep it up, So will I!
@physiopathopharmaco4190
5 жыл бұрын
Awesome 😎. Best of luck to you
@beautybeautyqueen6522
3 жыл бұрын
Thank you for such an amazing explanation♥️♥️
@AngryAmygdala
6 жыл бұрын
You guys are the best, up there with Osmosis. Please, keep up the great work. I am fully supporting you.
@physiopathopharmaco4190
6 жыл бұрын
Thats so kind of you - thanks for all your support and all the best!
@angusmack.2202
2 жыл бұрын
Thank You too much 4 this! You really saved my project!! Very Clear Explanation :D
@petertriantafillou8058
2 жыл бұрын
Great explanations Thanks so much!
@asmaarady2829
4 жыл бұрын
thank you ,it was awesome
@asmajama7947
3 жыл бұрын
Thank you so much for this amazing explanation🙏🏽
@physiopathopharmaco4190
3 жыл бұрын
You're so welcome!
@Elbuho17
2 жыл бұрын
BEAUTIFUL !
@user-zn6lk6gw5i
8 ай бұрын
رحم الله والديك
@xleo4096
11 ай бұрын
Helps a lot!
@Edward-ko9pn
6 жыл бұрын
It's amazing what us humans know about how the body works
@physiopathopharmaco4190
6 жыл бұрын
It truly is amazing
@brightdz2403
3 жыл бұрын
Nope we know less than 1 percent and every now and then we know more new things about that 1 percent.
@petersosa268
3 жыл бұрын
@@brightdz2403 That “1%” is a whole lot though lol
@brightdz2403
3 жыл бұрын
@@petersosa268 I said less than 1 😂😂😂😂
@Enthalpy--
2 жыл бұрын
Laugh at neuroscience and genomics
@xbieberlicious
3 жыл бұрын
really nice
@thatsverycool8264
4 жыл бұрын
Just a quick question about AntiTTG, where do these come from? Are they due to mutations in B cell genes? Do people without celiac also have them?
@sondosalmadhlouh7872
3 жыл бұрын
thank you!
@user-rk8bn3sm2g
5 жыл бұрын
That was great thanks!
@physiopathopharmaco4190
5 жыл бұрын
Thanks glad it was helpful
@giorgiobozzoni8681
6 жыл бұрын
thank you very much for your videos from Italy. i have a question for you and i hope you have time to answer me becuase this doubt stopped me to keep going studying. what happen to those who dont suffer coeliac disease, once the gliadin is inside the lamina propria of the gut? how do they break down gliadin to get its amminoacids? i mean gliadin goes intact into the lamina propria also for those who dont suffer coeliac disease, so they should have a way to digest it and get the AA. many foods have many allergen inside that cause immune response to those who actually havve food allergy for that specific allergen. but if i dont have allergy and i eat the food with allergen, and the allergen goes intact in the lamina propria without being digested by gut enzyme, how do i get its amminoacid anyway? my body wont waste them? thank you again
@physiopathopharmaco4190
6 жыл бұрын
There is decreased absorption for those with celiac disease due to morphological changes including Villous blunting and decreased surface area. Some don’t have these morphological changes despite having positive antibodies on a blood test. These may not have issues with absorption.
@lazymedic5988
6 жыл бұрын
Brilliant..plzz upload videos on bone pathology..ua awsome
@physiopathopharmaco4190
6 жыл бұрын
Do you have a particular pathology of the bones in mind and Ill get started
@lazymedic5988
6 жыл бұрын
PhysioPathoPharmaco it would b great if u upload video on detailed pathology of osteoarthritis n osteoporosis with complications..plzzz
@meryamlazrak1329
10 ай бұрын
thnk you sir
@tanmaymurur2377
4 жыл бұрын
Great video 👌 Isn't dermatitis herpetiformis also a manifestation of celiac disease owing to cross reaction of antibodies?
@jamyd7849
4 жыл бұрын
Yes it is
@matthewhill6949
5 жыл бұрын
Great video. How did you illustrate this? What programs did you use?
@Shilaan111
5 жыл бұрын
great one thank youuu:))
@physiopathopharmaco4190
5 жыл бұрын
You’re welcome
@sheilamacpherson4948
3 жыл бұрын
Way above me.
@nj2147
3 жыл бұрын
Thanks a lot..😊😊
@physiopathopharmaco4190
3 жыл бұрын
Most welcome 😊
@khawla-ez6cv
5 жыл бұрын
Thanks you
@physiopathopharmaco4190
5 жыл бұрын
You’re very welcome Khawla- all the best to you. 😀
@alysa4968
6 жыл бұрын
how was all of this going on inside me for 19 years and I didn't even know it
@alysa4968
6 жыл бұрын
also... really great video.
@physiopathopharmaco4190
6 жыл бұрын
Thanks for the comment, hope you're feeling better after going gluten free
@shamshahussein883
6 жыл бұрын
Alysa gluten free reverse able
@tahiransari3917
5 жыл бұрын
Helpful
@physiopathopharmaco4190
5 жыл бұрын
Thank you Tahir
@leavesofchange
Жыл бұрын
Does secalin get deamidated by tissue transglutaminase?
@fuscaotunado1337
5 жыл бұрын
Can you give us the references you used? @PhysioPathoPharmaco
@physiopathopharmaco4190
5 жыл бұрын
Much of that came from the Review article "The Role of Gluten in Celiac Disease and Type 1 Diabetes" published in the journal Nutrients.
@fuscaotunado1337
5 жыл бұрын
@@physiopathopharmaco4190 tks
@GauravSingh-tx4dt
5 жыл бұрын
Sir can you please share the source of information..
@physiopathopharmaco4190
5 жыл бұрын
Much of that came from the Review article "The Role of Gluten in Celiac Disease and Type 1 Diabetes" published in the journal Nutrients.
@wem3121
5 жыл бұрын
So the things that get the Disease started is a genetic predisposition of HLA II molecules AND an overexpression of CXC3 cytokines. Is that how it starts? And what about LT that escaped tolerance? Oh is that all those mechanisms at once? Thanks a bunch for the video. Im grateful 😍
@physiopathopharmaco4190
5 жыл бұрын
Yes several genetic factors can increase the risk - DQ2 and DQ8 and CXC3 cytokine expression
@NadineBotterman
4 жыл бұрын
Is it true that your intestines FULLY heal after a glutenfree diet?
@physiopathopharmaco4190
4 жыл бұрын
Yes but it can take up to at least a year.
@theEsperantist
Жыл бұрын
Celiacs need to use hookworms. They put my celiac into full remission.
@khankaseparhnahagee9530
4 жыл бұрын
Scientist should do something for this
@grizzy315
4 жыл бұрын
khan kase parhna ha gee yes, but there is not enough awareness for most scientists to research on the disease. its sucks but hopefully in the long run treatment is more effective.
@khankaseparhnahagee9530
4 жыл бұрын
Celiac is also spreading v quickly in the world like corona
@Cr7goat.85
8 күн бұрын
Could you speak a little bit slower next time?
@UmeshKumar-xu2ng
2 жыл бұрын
Sir i have celiac disease and suffering from lack of sleep is this normal?pls reply🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🏻
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