Then we REALLY start treading into the hypothetical science haha
@Brains45636
4 жыл бұрын
@@Roanokereviews yess
@PapaThiccc
4 жыл бұрын
I had to watch this vid twice. I got lost in your eyes. 😂
@AnimeShinigami13
4 жыл бұрын
*brightens at the start of the video* There you are. I was wondering where that lovely baritone was actually coming from. :D I thought all you were was a disembodied voice! no wonder you got a fiancé with that nice looking nerd face, what took her so long?
@Dynamic_madman117
4 жыл бұрын
Look at this chad, absolute unit
@Roanokereviews
4 жыл бұрын
Ayyyyy thanks man! haha
@AnimeShinigami13
4 жыл бұрын
don't let his muscles know that or he'll shrink before your eyes!
@MakeTrapsGreatAgain
4 жыл бұрын
Freedom Unit
@BerserkJess
2 жыл бұрын
Would smash
@thezambambo2184
4 жыл бұрын
This honestly helped me more than High School Biology while studying because I can actually understand it
@Roanokereviews
4 жыл бұрын
Glad it helps man!
@HarshPTHESNAKEFIST
4 жыл бұрын
👍
@dldoubleg2915
4 жыл бұрын
Roanoke hit me with biology, philosophy at 7:51, and also thermodynamics. Renaissance man
@Roanokereviews
4 жыл бұрын
Ya love to see it! haha
@frankboff1260
11 ай бұрын
‘Prions that clump together, stay together’.
@Odysseus405
4 жыл бұрын
Hunting in my area has been heavily impacted by this. Shits crazy if you come across what you think to be an animal corpse that somehow still walks.
@dumbassenby20002
4 жыл бұрын
The swollest scientist on KZitem 😂
@Roanokereviews
4 жыл бұрын
I must obtain swoler levels! Ive been slacking lately, winter has me in hibernation mode haha
@masterzoroark6664
4 жыл бұрын
Now get him to team up with that guy making laser bazooka aka the sexiest nerd around, and guess they gonna make their own spartan program
@masterzoroark6664
4 жыл бұрын
@@TheGoodCrusader yes
@thedoruk6324
4 жыл бұрын
The Scientist explains the *nightmare fuel* once again! 🅱rain amoebea next? (I still remember this presented as the zombie deers)
@Roanokereviews
4 жыл бұрын
That would be a cool idea as well! Hope you enjoyed it bro!
@thedoruk6324
4 жыл бұрын
@@Roanokereviews İt was great, I always want to learn what's the mass hysteria about the infected deers about
@Lysikor000
4 жыл бұрын
TL;DR Shit be wack. Jokes aside, this video is very informative. I enjoy learning new information.
@Roanokereviews
4 жыл бұрын
Glad you enjoyed it bro!
@mr.eccentricthelich
4 жыл бұрын
Holy crap this is horrifying
@Roanokereviews
4 жыл бұрын
I agree, losing my brain is my biggest fear
@rudesoup7828
4 жыл бұрын
In my anatomy & physiology class we watched a documentary on the UK's BSE outbreak. Back in the 80s the protein only hypothesis was somewhat controversial because proteins weren't capable of reproducing like microorganisms. Then some dude noticed that chains of proteins had built up in samples of BSE infected brains. Eventually it was also discovered that abnormal proteins could bind to & convert a normal protein into an identical abnormal protein, & they can be denatured by excess heat, cold, acids, & bases. Also Roanoke dresses like an uber boomer & it amuses me.
@Roanokereviews
4 жыл бұрын
thats what is absolutely insane about those proteins, their resistance to virtually everything, but they can be destroyed with enough energy, unfortunately it destroys the organism too and Yes! I enjoy my fiji shirt :)
@kingkazumaone9548
4 жыл бұрын
I like the new style but it's a little bit echoey and a tad bit quieter
@Roanokereviews
4 жыл бұрын
I think I may be able to alleviate the echo, but the voice is quieter, Ill take that into consideration in the next videos!
@Ozbubblez
4 жыл бұрын
Very very noice. Lookin good my dude What mic are you using?
@Roanokereviews
4 жыл бұрын
Thanks bro! its this craptastic mic that came with the camera, gonna need to figure out how I can hook this up to my yeti
@linkdogdog98
4 жыл бұрын
Love the shirt my dude
@Roanokereviews
4 жыл бұрын
its one of my favorites! haha
@justafriendlycryptid
Жыл бұрын
It took me a moment to realize I had heard your voice before- as soon as you said 'meat suit' it clicked. I don't know how I got here exactly but hey I am genuinely fascinated.
@marcusarygmail
2 жыл бұрын
This dude has another KZitem channel I swear. His voice sounds just like the guy who covers diseases in video games and movies.
@imnotchikao6317
4 жыл бұрын
That chest hair 😘
@Roanokereviews
4 жыл бұрын
I was editing and realized I probably needed to hit that second button haha
@CrimsontC720
2 жыл бұрын
Just found out about this channel and wondered if you had talked about this. My fiance's mom died from CJD. Was absolutely heartbreaking to see her mom degrade like that. They still don't know what caused it but they are fairly certain that it was the genetic form. Which means my fiance has a 50/50 chance of the same thing happening to her.
@DannyD-lr5yg
2 жыл бұрын
FYI there are things your fiancée can do to stack the deck in her favor! Stress, lack of sleep, processed meats (yes, even if we’re not talking about vCJD/the bovine one, and even if the meat is not beef), general inflammation (from things like viruses/diseases, lack of sleep, high sugar diet, stress, etc), and other things are risk factors for developing prion diseases. She’ll probably be ok. But, wishing y’all the best 💖
@kevinmurphy5878
9 ай бұрын
@@DannyD-lr5ygwhere did you get that info about the risk factors? Ive been reading about this topic for a while and Id like to learn about that
@eray9934
7 ай бұрын
I am so sorry. It sounds like an absolutely horrible way to go.
@loganwalsh8479
4 жыл бұрын
You should put the images relating to the topic in the background behind you. Also the thought that CWD can jump species to humans is horrifying
@Roanokereviews
4 жыл бұрын
A good idea, I can see if that would be possible!
@Agsotro
4 жыл бұрын
I listen to this stuff like a podcast. Keeps me entertained at work, mate. It really takes the edge off of being woefully overqualified for my job.
@S1lva139
4 жыл бұрын
Keep them coming man well done presentation my dude. Despite that fact that near everything you cover is nightmare fuel I love learning new stuff.
@Roanokereviews
4 жыл бұрын
Excellent! thank you for the feedback bro! glad you enjoyed it! :)
@ihwp12
4 жыл бұрын
Enjoyed the video as usual, (I love learning) & your good at breaking down information in a non-confusing way. I do suggest that you please use the green screen to continuously display the images (as this helps me learn cuz the visual info sticks with me). Great channel, 1 of my favorites actually. Keep up the good work and thanks for the video on the Krogan! Very much appreciated!
@Roanokereviews
4 жыл бұрын
I might be able to do that in the future! biggest concern is me walking around in front of what I am talking about haha but we will see, also no probs my guy!
@FriedCarp
4 жыл бұрын
Thank you for explaining this. I’ve been hearing a bunch of information about this and I wasn’t sure what was truth and what was fiction. Thanks for clearing this up for me
@tone1446
2 жыл бұрын
Enlightning, unsettling and feels eerily current. thank you so much :)
@musashimcclellan681
4 жыл бұрын
I like this. It's like Sci show but completely about diseases
@Roanokereviews
4 жыл бұрын
Glad you like the channel direction!
@liamarmstrong2799
4 жыл бұрын
You know this makes me wonder whether prokarotes can produce prions if not then the production of prions may have something to do with organelles only found in eukaryotes like the golgi body. Also if we are capable of fully finding the molecular structure of the most dangerous prions maybe in the not too far future genetic engineers will produce an enzyme the can detect and hydrolyse these proteins into harmless amino acids.
@Roanokereviews
4 жыл бұрын
I believe its only Eukaryotes that really produce it, but thats a really good question my guy!
@salimsadmanalvieee8965
4 жыл бұрын
from one biology lover to another I salute you the best channel :) and you deserve more subs please keep the videos coming cause thirst for knowledge is a real deal
@samwil0_9
4 жыл бұрын
I liked the format, it's nice for a first try. Also like how this adds up to my biology class.
@Roanokereviews
4 жыл бұрын
and it should get better! thank you for the feedback bro!
@tannerlamont
4 жыл бұрын
Good stuff! Clear and concise
@henryburness3580
2 жыл бұрын
Grasses taking up the prions really scares me .Keep up the good work
@isaacyanez7996
4 жыл бұрын
o boi, seeing you there makes things more... how can i tell you... sociable(?.Anyway, great work man!
@Roanokereviews
4 жыл бұрын
Thanks bro! and I enjoyed being infront of the camera, may need to refine a few things though lol
@TheSeerSacrifice
3 жыл бұрын
problem is those that choose to be ignorant about this but know better that hunt, set up feeding stations knowing this is on the rampage and getting worse.
@Fidgetthebatpony
4 жыл бұрын
The way you were listing the symptoms reminded me of how commercials for medications are here in the US
@ladyfaeryj5108
4 жыл бұрын
You did great hun!
@Isador11
4 жыл бұрын
Broanoke is back and educating, nice ! thanks a lot for bringing all this hard to digest science in a format i am able to understand
@Roanokereviews
4 жыл бұрын
Excellent! that is exactly what I am going for! glad I can help :)
@patriciusvunkempen102
4 жыл бұрын
handsome medical, also cool shirt bro
@Roanokereviews
4 жыл бұрын
Thank you for the compliment broham! and I am glad you like the fiji shirt! haha
@68Fourty72
2 жыл бұрын
"As I understand Prions, certain funguses have Prions."
@eddiegrathwohl624
4 жыл бұрын
Lovin the Hawaiian shirt bro lol. Great video though, we had an issue with the wasting disease here in Ohio with dear a few years back.
@Roanokereviews
4 жыл бұрын
Scary stuff! And thanks man!
@eddiegrathwohl624
4 жыл бұрын
@@Roanokereviews man you work harder than I do lol. Keep up the amazing work!!!!
@localbigfoot8217
4 жыл бұрын
Sounds like a fun weekend
@Roanokereviews
4 жыл бұрын
Yah but a year later it sucks!
@Cosmystery
4 жыл бұрын
Just been studying about CJD. Didn’t know u did a vid on it nice bro
@briana7457
2 жыл бұрын
Thanks, liked it!
@Rodragon-ez9hd
4 жыл бұрын
its a really cool format hope you keep it up
@Roanokereviews
4 жыл бұрын
I intend to!
@spaceman6463
4 жыл бұрын
Good video my dude
@Roanokereviews
4 жыл бұрын
thanks broham!
@davinthule249
4 жыл бұрын
Dude you got this. Great video, keep doing what you're doing 10/10
@Roanokereviews
4 жыл бұрын
Thanks bro! glad you enjoyed it!
@fernandosalvador369
4 жыл бұрын
I'm here, chillin', watching one episode after the other. Straight terrified of proteins.
@Chaos-Devil51
4 жыл бұрын
amount all the diseases and syndromes that we have prion disease terrify me the most luckily they are indeed rare.
@Roanokereviews
4 жыл бұрын
something about taking out the brain, seems awful
@Chaos-Devil51
4 жыл бұрын
@@Roanokereviews it's not just that the fact that there's no treatment for it.
@ShoutingOmega
4 жыл бұрын
quite the amazing shirt my dude
@JenFoxworth
3 жыл бұрын
Dang, first time seein' ya, look great good indeed. Very nice!
@codyos16
4 жыл бұрын
My grandfather died from CJD. He went from normal to deceased in like 3 1/2 months.
@somneang87time29
3 жыл бұрын
What’s the test of CJD? MRI,CT scan or blood work?
@codyos16
3 жыл бұрын
@@somneang87time29 various types of brain scans are typically used but thats only after onset and only to narrow it down. Confirmation of the diagnosis can only be done post-mortem to be sure. There are genetic test that can be done beforehand, but they only show if you have the genetic markers for it, not if you will definitely get it. Also, even if you dont have the genes that could cause it to develop, you can still get it from environmental sources like food, groundwater, etc. or you could develop it from spontaneous gene miscoding or mutation.
@lucianaromulus1408
2 жыл бұрын
Holy shit you can get it randomly? That's wild, I thought it had to be consumed. How did he get it ? I'm so sorry this happened to you. Brain issues are the worst and most heart breaking.
@lostoastbread5744
9 ай бұрын
Hell yeah another Roanoke channel to subscribe too
@JuanMartinez-nh3pn
4 жыл бұрын
Love the new channel my dude. It feels like something is missing besides background images but I cant put my finger on it.
@Roanokereviews
4 жыл бұрын
still finding my way with that, the biggest issue is if the background is too busy, Ill get lost in it haha
@DrNoSleep
4 жыл бұрын
Joe Rogan sent me here. I was not disappointed.
@Roanokereviews
4 жыл бұрын
oh nice, was he talking about CWD on his podcast?
@DrNoSleep
4 жыл бұрын
@@Roanokereviews Yep! I'm sure you'll be getting an influx of views haha. Great content by the way!! :)
@RenchKid
4 жыл бұрын
You did a really good job, I like the video this way it’s perfect
@philipfreeman72
Жыл бұрын
A map of the current affected area would be good .
@stephenconnell
4 жыл бұрын
Fantastic Explanation. One of my In laws contracted /developed Motor Neuron disease and was dead in 3 months. Scary disease. I remember reading an article that put foreword the idea of countering the enemy prion with another "created /altered prion that negates its folding effect. Have you come across an speculative Prion counter measures?
@diekrahe.
4 жыл бұрын
Nice work as always. I can't wait to watch this channel grow like the other one.
@Roanokereviews
4 жыл бұрын
that would be cool! glad you are along for the ride! :)
@jurijsitar5567
4 жыл бұрын
The video was great. Thank you for making this and i hope you will continue to do more. Also you were a bit out of focus on the camera.
@Roanokereviews
4 жыл бұрын
Second video should fix virtually all these issues! New mic as well, glad you are enjoying the channel direction though!
@jayant4394
4 жыл бұрын
Educative and entertaining. Roanoke is the ultimate Chad hahaha🤣 My only change would be there is not enough feets yet Awesome vid and content as always bro👏👏
@Roanokereviews
4 жыл бұрын
we will get them feets soon enough! haha glad you are enjoying the channel bro!
@masterzoroark6664
4 жыл бұрын
Prion is basically rouge protein that spreads it's influence among other proteins
@somneang87time29
3 жыл бұрын
Agree with Too scary disease ever
@andresmonserratte6592
Жыл бұрын
thanks man lve this
@falloutwubb557
4 жыл бұрын
Swol in the brain Swol in the braun
@nubs4346
2 жыл бұрын
I literally just laughed my butt off, "if it can jump the spiecies barrier, that means it can jump our spicies barrier, its not a good time for that". Posted literally right before covid spread around the world.
@CODAZ06
4 жыл бұрын
Love the content dude and the new channel!
@Roanokereviews
4 жыл бұрын
Glad you are enjoying it! :)
@redohealer2
4 жыл бұрын
Now you look different again
@Roanokereviews
4 жыл бұрын
Next time, Ill be much more swole haha
@redohealer2
4 жыл бұрын
@@Roanokereviews lore/morphology of your cat when?
@DARKWIZRDDUDE
4 жыл бұрын
When your trying to be super fan but forget ya boi has a second channel
@Roanokereviews
4 жыл бұрын
Ayyyy! thanks for coming over bro!
@MegamonK17
4 жыл бұрын
Wow, the only time I've seen you besides in this video is in one of your black mesa live streams, this is related to dead island's mutated kuru.
@Roanokereviews
4 жыл бұрын
I wasnt aware that was in dead island! Thats pretty interesting
@duran4689
2 жыл бұрын
I thought the body could release the FPR or something that will destroy a misflolded protein. In response Expands the ER and releases chaperons to capture the protein from escaping. I’m currently in a college cell biology class and I swear we went over something like that incase a protein does misfold
@Rootinator-nm4ow
4 жыл бұрын
Hi Roanoke I really love your content and I’ve always had a deep fond for science. Seriously no one ever wants to talk about this but I have several learning disorders and I was wondering if maybe as your are a type of scientist that if theirs anything that may treat them let me know it’s impacted my life horrible socially and career wise despite being a intelligent normal human being lol keep up good work
@Roanokereviews
4 жыл бұрын
Technically, most things could be fixed hopefully in the future at a genetic level, but regardless of that, hang in there man, you are an intelligent individual who can do well in their own right
@Rootinator-nm4ow
4 жыл бұрын
Croatoan Medical thank you!! That means a lot me I’m sure it’s not exactly in your field but it was caused by environmental brain damage thank god for STEM CELLS! Take care Roanoke!
@meau400
4 жыл бұрын
Hey thanks for the introduction to prions, good content could do a little better with the audio and maybe some images on the background to complement the subject youre talking other than that you hit right on the spot :D
@Roanokereviews
4 жыл бұрын
Got something coming sunday to rectify that!
@ypcomchic
2 жыл бұрын
Update - CWD DOES spread to humans.
@user-xz5qi7wq1u
9 ай бұрын
Yep.this didn't age well... or it did...depends on who you are🤔😂
@akaniotevanos9861
4 жыл бұрын
Hey where's your RIG suit and plasma cutter? At least thats what i thought youd be wearing :P
@Roanokereviews
4 жыл бұрын
Bruh if I could get a rig, I am just Isaac on the off season haha
@corbin6866
Жыл бұрын
I shall never leave my house again
@reanimationeas342
2 жыл бұрын
Maybe if a person gets exposed enough, it could eventually jump to humans
@andromidas920
4 жыл бұрын
Our bio boi hitting those swole goals
@Roanokereviews
4 жыл бұрын
lord I wish! been lazy as all getout the last few weeks concerning the gym haha
@bluemoon9501
4 жыл бұрын
Damn. His good looking.👀
@monsterEN98
4 жыл бұрын
Who needs school and debt when I could learn from u one video closer to becoming a Biologist😂
@Roanokereviews
4 жыл бұрын
Ascend with us biologists and taste victory everlasting! Haha
@axemanh141
4 жыл бұрын
Could you possibly do a video on bacteriophages
@silent_stalker3687
4 жыл бұрын
What if SCP 628 is just a prion disease that hasn’t killed it’s host?
@Roanokereviews
4 жыл бұрын
Need to learn about that one!
@silent_stalker3687
4 жыл бұрын
Croatoan Medical Typo, 682 ^^; I said 628 not 682
@RVR121
4 жыл бұрын
3:45 it is like the thing from the movie "The thing" D:
@Esoteric_Loonaism
4 жыл бұрын
I feel like this Prion is comparable to the Vegetals in the Meme Man and Orang Surreal saga
@Roanokereviews
4 жыл бұрын
I need to look this up now
@Galen55
3 жыл бұрын
Watching in 2020, this is just what is coming in 2021. Mad cow disease MKII
@Roanokereviews
3 жыл бұрын
Luckily we are more aware of it and it doesnt spread quite like a virus would!
@Galen55
3 жыл бұрын
@@Roanokereviews yeah, but the population of ignoramus continues to grow... I don't think we can stop it with the morons dragging us off course.
@retrowave762
4 жыл бұрын
wait that was a greenscreen? i thought you were just standing in your garage
@gk21wolf60
4 жыл бұрын
Love it
@Roanokereviews
4 жыл бұрын
Excellent! glad to hear it bro!
@akanthony100
4 жыл бұрын
I'm thirsty for some water
@promeneuzivotu117
4 жыл бұрын
So Prion is like combination of infection and poisoning at the same time?
@cocoa1oo2
4 жыл бұрын
you you big boi
@Roanokereviews
4 жыл бұрын
Ayyyyyyyy!
@mr.eccentricthelich
4 жыл бұрын
But cool vid
@Roanokereviews
4 жыл бұрын
Thanks bro!
@libertadvalerio870
3 жыл бұрын
Why is no one sounding the alarm about this?
@--------352
4 жыл бұрын
*this boi is thicc*
@Roanokereviews
4 жыл бұрын
;)
@PapaThiccc
4 жыл бұрын
I live in Alaska and this shit scares me. I go hunting every year and I live in a rural area rural area. So I'm far more likely to come into contact with it.
@Roanokereviews
4 жыл бұрын
Make sure to observe your prey!
@PapaThiccc
4 жыл бұрын
@@Roanokereviews I know you said it's able to affect Caribou but do you know if it effects moose as well?
@ornokur6315
4 жыл бұрын
CWD probably is being exacerbated by the deer and elk's exploding population by lack of predation and lack of hunting in suburban populations.
@Roanokereviews
4 жыл бұрын
thats a good point, and if it does spread, we may have to actually devote tax dollars to control the issue, I know few hunters who would love to get on the ground floor of that haha
@ornokur6315
4 жыл бұрын
@@Roanokereviews It very interesting how the explosion in the elk's population effected Yellowstone NP. Before wolves were reintroduced to suppress the population, the massive herds of elk would eat all the angiosperm tree species saplings, as the oldest individuals died a younger population of trees couldn't replace them. It got so serious that riparian areas were destroyed. Without trees that make those habitats such as cotton woods, willows habitats for other animals that needed them suffered too as a result, as well as the problem of diseases running rampant in the elk population without wolves to pick off the ill individuals. Here's a good video talking about this. kzitem.info/news/bejne/2qmXm4N4oYqrYIY
@roboticrebel4092
4 жыл бұрын
is it just me or is the camera out of focus?
@Roanokereviews
4 жыл бұрын
it is! I need to put an x on the ground where its focused
@roboticrebel4092
4 жыл бұрын
@@Roanokereviews Good luck. I've been enjoying your analytical and informative videos about the biology of various abominations in video games (some of which keep me up at night now, thanks) and you got me really exited about crispr on this channel Keep it up
@infinityzer054
9 ай бұрын
Why can’t humans be as durable as a misfolded prion? Bacteriophage vs wasting Or crisper
@robertmcmillian7239
4 жыл бұрын
Hey Roanoke I was wondering if you can talk about the disease cmt my grandfather has it sadly but I would love to learn more about it
@DASBIGUN
4 жыл бұрын
@Croatoan Medical Could u burn it in intense enough heat? or is it practically involnerable to heat?
@John-X
4 жыл бұрын
Did you know that people who lived in the UK during the 80's aren't allowed to donate blood anywhere else in the world because they may be incubating Mad Cow Disease? CWD is the same type of disease, but a lot worse. So I guess my question to you is: if humans who have been around CWD infected plants and animals, and are currently incubating the disease, how is intense heat gonna help them? It's like *_"Yeah bro, let's burn this mf, that'll cure the bitch."_*
@lucianaromulus1408
2 жыл бұрын
I'm pretty sure it takes immense heat to destroy them, like past the melting point for steel. I could be wrong on the specifics but I know not basic cooking of meat will kill these prions.
@lindasapiecha2515
2 жыл бұрын
Very good but it is pronounced Yakob not Jacob
@mastatheif9909
4 жыл бұрын
Wait if we can isolate the protein can we just yeet it out 🧐
@Roanokereviews
4 жыл бұрын
Alas, not yet, mainly because its inside your head which is very tough to get to
@mastatheif9909
4 жыл бұрын
@@Roanokereviews why doesn't chemotherapy work?
@optimisticexistentialnihilism9
4 жыл бұрын
I hope prion disease as a whole dont start out as rare slaw burn into a epidemic that spreads rapidly.
@Roanokereviews
4 жыл бұрын
thats actually what I think about too, what if we are witnessing the beginning of a plague situation? but the good thing is, we can control it and quarantines are highly effective
@theusefulmorons1330
4 жыл бұрын
Is that a green screen I see? Time for some editing
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