CLP 2023: QTc Prolongation and Psychotropic Medications: Complex Clinical Cases
This fully interactive workshop is targeted to participants of all stages of learning and experience. The workshop will build on the core concepts that have been presented in prior ACLP Pre-Conferencet Skills Courses by utilizing complex clinical case examples that consider various determinants of health. Though we have presented on this topic as a Skills Course in the past several years, we chose to submit as a workshop this year to make the learning experience available to all meeting attendees.
We will begin with a brief review of the QT interval and an update on psychotropic medications that prolong the QTc. This review will include updates in the literature from the past year, including evidence for newly approved medications, a focus on droperidol (increasingly used again), and a step-by-step overview of QT measurement, heart rate correction, and clinical application. Using audience polling, discussion and a series of new clinical cases we will then discuss the approach to risk stratification and mitigation for use of psychotropic medications in patients at risk for TdP and SCD. Cases will highlight the impact of environmental-biopsychosocial determinants of health on the risk of SCD and high-yield strategies for various practice settings and patient populations. High risk populations include patients with: pregnancy, opioid use disorder treated with methadone, implanted cardiac devices, known mutations of genes associated with SCD, end-stage renal disease receiving hemodialysis, treatment in resource-poor clinical settings, and severe medical/surgical illness requiring intensive level of care. Cases will become increasingly complex as the learner becomes more confident. The workshop will conclude with a Q&A with the panel of speaker.
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