My daughter is homeschooled and will be watching this, there aren’t enough women in science and this simple explanation of a complex subject is something we need far more of, thank you. Great video.
@eddie1975utube
2 жыл бұрын
So nice to read your comment. Where I live in Alabama, 99% of home schooling parents would never show their kid such a video.
@altareggo
6 жыл бұрын
Truly an excellent presentation!!! Thank you so much for putting these online: its a great service and helps the general public understand complex matters by giving a lot of background material without anything overly technical.
@mohammedalhuneini219
2 жыл бұрын
Excellent presentation After minute 25:00 there is error in the Hb curve The fetal Hb (HbF) she is talking about is actually made of alpha/gamma not alpha/delta Otherwise a very wonderful talk
@jasimine_b
6 жыл бұрын
awesome on so many levels, no wonder she was exhausted in the end! i wish she'd make a whole lecture series of this with much more detail...
@ambrosewanjala8843
2 жыл бұрын
Seconded. Truly awesome
@stephanieparker1250
3 жыл бұрын
In case anyone is curious, her beautiful Irish name is pronounced “ee-fa”. 🥰
@whirledpeas3477
3 жыл бұрын
Cool 😎
@kingalf4828
2 жыл бұрын
I was literally just gonna look that up.. cheers
@Duckfest
2 жыл бұрын
Thanks. I don't recall ever seeing a name as Irish as hers. I love it. I also think Professor Aoife McLysaght would be an excellent name for a character in a fantasy novel.
@dboots123
2 жыл бұрын
Her name is the first reason I clicked for this video. Thanks for the info 🙏🏼
2 жыл бұрын
thanks !
@edwardlee2794
5 жыл бұрын
Charming with a purpose. Salute to The speaker and RI.
@KipIngram
3 жыл бұрын
You really don't need to waste time debunking creationism. The people that back it aren't listening anyway.
@NicleT
2 жыл бұрын
Excellent presentation, very insightful. Thank you Dr. McLysaght, and thanks to the Ri.
@eliastouil7686
6 жыл бұрын
Introduction 00:00 I will talk about evolutionary genetics 00:00 how evolution relates to the field of biology 03:50 What is a gene ? 07:43 DNA, duplicating genes 11:25 Evolution by gene duplication Examples of gene duplication 13:55 Human sense of smell 16:45 Evolution of colour vision 20:20 Globins What can we understand 26:40 Patterns of evolution 31:50 Why is there so much diversity (vertebrates/humans) 36:20 When gene duplication is problematic (pathology) 43:30 What to look for in DNA 48:15 Dosage sensitive genes
@spook_dad
5 жыл бұрын
please link to the smell your bum quote
@allwinaugustine
4 жыл бұрын
Good job elias!
@chipparker3950
4 жыл бұрын
A patently improvable statement. Amazing arrogance.
@jamesdolan4042
4 жыл бұрын
@@chipparker3950 I did not hear say anything about improvable adaptations just for the sake of it. She spoke of how olfactory genes in DNA duplicted and simultaneously changed ever so slightly to optimise survival for the species at that juncture in time. And conversely how these genes become redundant when optimizing survival does not need them. There was nothing arrogant about her iinformed and learned opinion. If you think differently I would appreciate you explaining it.
@BenjWarrant
5 жыл бұрын
The Irish delightfully comes out more and more as she carries on speaking.
@martinpollard8846
4 жыл бұрын
I "tink" you're right
@ebrewste
2 жыл бұрын
Some people really have a gift for presenting. She is incredible. There is some interesting cross pollination of ideas that adds something to what is more traditional material I have seen on the subject.
@boblenk
6 жыл бұрын
Thank you, Aoife, for acknowledging Susumu Ohno. He is one of my heros!
@dmitritobias
5 жыл бұрын
her name. what a kickass name. sounds like it's destined for greatness. i bet when she tried to make an account and typed just her first name, google was like... yeah that's available.
@shrikantkukreti7068
3 жыл бұрын
What a Brilliant talk. So informative, simple and elegant. Congrats !!
@RochelleM491
2 жыл бұрын
This is one amazing, professional well produced video, I hope she has the time, energy and resources to creates many more videos like this which I really appreciate..!
@nycbearff
3 жыл бұрын
This is an excellent lecture, well presented and clear. Thanks, Dr. McLysaght! Thanks, Royal Institution!
@miTTTir
7 жыл бұрын
This talk showed me something which was hiding in the plain sight right in front of my nose. Awesome presentation. Fascinating research.
@Sailright21
9 жыл бұрын
Excellent! Copy number variation explained and explained beautifully!
@pecan11
Жыл бұрын
This lecture is one of the most incredible I have seen. I have a personal interest in evolutionary biology and I studied bio in college. Remarkable insight with this research
@rolfw2336
6 жыл бұрын
This was a great talk. I never knew about the 4X event in human evolution. Thank you Dr. M!
@illumencouk
2 жыл бұрын
If you imagine a scenario where you start off with everybody having a correctly balanced gene pool as akin to an I.T department un-boxing a brand new network of personal computers, you can begin to mentally visualise how interactions between different users will over time actually diminish the higher state into a altered state. The practical day to day operations of file sharing, downloading and uploading, will transform our 'factory' (olfactory) settings into individual states. Co-operation and allocation of a finite set of resources is required and a hierarchical framework developed. I could go on but I think you can see the similarities?
@matthewfeeley6226
3 жыл бұрын
Really enjoyed the performance, thankyou for sharing your knowledge and skill it was great to learn so much about standing up and delivering a complicated topic. Thankyou so much.
@wendellwiggins3776
2 жыл бұрын
I love the interest in this wonderful informative magical lecture. Simple yet complex enough to follow. I simply find the info so fascinating because the intricacies of life are so wonderful. The UNI-verse with all of It's elements are nobless than magical.
@kristineinarsdottir7404
10 жыл бұрын
Aoife McLysaght I really enjoyed this lecture. Your view on life is extraordinary!
@martingachagua4554
4 жыл бұрын
Eazzy To Take A Listen. She Introduced And Explained Abstract Things Flawlessly. Very Few Assumptions Intended On The Part Of The Listener. Can Be A Good Introductory Course To Genetics As A Whole. May I Say The Voice Was "Tonal" To Listen To . . .
@DavoidJohnson
5 жыл бұрын
Exceptional seamless progression of knowledge. Other presenters should try to emulate this. Best of luck.
@Anza_34832
3 жыл бұрын
Not being an expert in the field of biology, this lecture was a real eye opener!
@heinpereboom5521
2 жыл бұрын
Maybe that's why?
@henriroggeman7267
6 жыл бұрын
You've given us more than just a sense. Thank you for an excellent talk! :-)
@SONofaGoddess
3 жыл бұрын
Take a breath.. you nailed it! 👌🏽
@paulodetarsoarrudacorreia6138
5 жыл бұрын
Excellent presentation. Congratulations !
@ryanmckenna2047
2 жыл бұрын
An excellent presentation! That research can be guided so effectively through the application of a a statistician's mindset. A simple principle - That the very absence of something to measure is significant and it reveals so much, fantastic!
@heinpereboom5521
2 жыл бұрын
Yes, a nice presentation, but what did she really say about the beginning of life? I only heard what happened after that beginning.
@infocentrousmajac
2 жыл бұрын
Beautifully explained and very engaging talk.
@VvDOPAMEANvV
10 жыл бұрын
Excellent subject and content!
@JamesTrue
Жыл бұрын
Watching someone insist the only way to explain things is with evolution reminds me of how much we need to evolve our thinking.
@richardbradley1532
2 жыл бұрын
Going to have to watch this again to understand better.
@brahmburgers
8 жыл бұрын
What a lovely woman! ....her person, her insight, and the way she shares it with others.
@cirusrome4086
2 жыл бұрын
Learned great information- thanks 🙏
@RalphDratman
10 жыл бұрын
This is great. Thank you Aoife McLysaght.
@aoifemclysaght3586
10 жыл бұрын
Thank you :-)
@RalphDratman
10 жыл бұрын
Aoife McLysaght You explain things clearly, you look good and you sound great. I would like to watch any other lectures you might have online. If you don't have any other videos online yet, perhaps you would consider making some? You don't need anything more than an iPhone, iPad or Android device to accomplish that. Having a helper to hold the camera makes things easier, but that is optional. You can do an entire video by yourself.
@tantiwahopak101
6 жыл бұрын
@The Truth of the Matter yes. She is real. Check it out.
@tantiwahopak101
6 жыл бұрын
@The Truth of the Matter wow so this is ur reason for her to not being real? Not all people are famous u know that right?
@EricDittmarrice
6 жыл бұрын
@@aoifemclysaght3586 Thank you. Stay gold!
@kamrupexpress
3 жыл бұрын
Very interesting lecture. Even as a math person I enjoyed it
@heinpereboom5521
2 жыл бұрын
Perhaps you can calculate the probability that DNA will arise spontaneously or that the 20 proteins are in the right combination? That DNA, the most complicated molecule, still has to be lucky that it is in a very life-friendly environment, the chance then becomes slightly less.
@quill444
5 жыл бұрын
What a powerful, pleasant, presentation: Aoife has the presence of an actress, one who could easily carry a starring role in a movie or television series! - j q t -
@hemant05
2 жыл бұрын
Evolution is the most fascinating subject and most likely greatest things humans discovered
@mikefinn
2 жыл бұрын
And, evolution is driven by the Energetic Principle of Natural Selection: traits are favored that help find, digest, store, and utilize energy. This is the basis of convergent evolution.
@lennymartin4693
4 жыл бұрын
I love super smart women
@LuciFeric137
3 жыл бұрын
Beautiful, lyric. I can listen to her pronunciation all night..
@sighthoundman
5 жыл бұрын
In programming language: a gene is a variable length field within the DNA database.
@Trunks47r786
10 жыл бұрын
Amazing presentation! A good overview of genetics but I wish Dr McLysaght had gone into the biochemistry a little bit more. Very interesting. Thank you.
@mrartwatcher
9 жыл бұрын
the bio chemistry would only further support intelligent design as the question what came first ,the chicken or the egg ?
@Trunks47r786
9 жыл бұрын
mrartwatcher How so?
@HO-bndk
6 жыл бұрын
The egg came first. Dinosaurs were laying eggs millions of years before birds existed.
@mikebellamy
6 жыл бұрын
Dinosaurs may lay eggs for ever but they will never produce anything with feathers on it..
@juniorloaf12
5 жыл бұрын
Mike Bellamy dinosaurs had feathers
@mihaliprefti2507
2 жыл бұрын
How educational! Thank you, Professor!
@jamesconner8275
6 жыл бұрын
Excellent, even I understand it and I've been accused if missing a chunk of my DNA. When she pronounces "think" does she actually say "tink?" Must be in the Irish DNA.
@danielash1704
2 жыл бұрын
Frequency has it's part on evolution
@dimitrioskalfakis
2 жыл бұрын
what a spirited and knowledgeable girl.
@akashdasgupta6692
10 жыл бұрын
Very informative. What do you think of Dawkins's definition of a gene, where it is defined as the smallest section of a chromosome that can potentially last over deep time? The definition you give, which is a gene is a section of a chromosome that codes for a certain chain of amino acids, is what is taught in school. However in 'the selfish gene', Dawkins tells us something different. Is there a 'conventional' definition, or is the issue still subject to debate?
@Necromycin
6 жыл бұрын
Beautifully explained
@arnoldleaf4521
5 жыл бұрын
" too much of a good thing" was fab found it really informative ! Thanks
@maxdoubt5219
8 жыл бұрын
I love ice cream and cheeseburgers so I am quite happy to carry the mutation that let's me stay lactose tolerant all my life. But I don't like fruit and veg, so I want my Ligo gene back! Heh. This presentation is just as engaging as any by the cosmologists or physicists.
@patrick6110
2 жыл бұрын
Brilliant expose, thank you
@peterwhyte317
3 жыл бұрын
Thank you! I heard every word, and understood everything.
@peterdriscoll4070
6 жыл бұрын
Fascinating talk. Just awesome.
@robotaholic
5 жыл бұрын
I loved this lecture
@mozkitolife5437
9 жыл бұрын
Invoking ID or Creationism comes easier to theists than learning new concepts as an adult because they've been exposed to these cultural, subjective ideas from birth. It's easy to speak the language you've grown up with... it's just who you are. Attempting to speak another language takes up to a year of learning. The same goes for religion. Their brains are structured for religiosity due to a congenital/pedagological indoctrination. It's not their fault but you can't force these people to suddenly change their neurology which was established over decades. They have to want to learn and change themselves but that will only happen if they're intelligent enough. Unfortunately, religiosity is negatively correlated with education/intelligence.
@nu.wa.n
8 жыл бұрын
organized religion is no different from cults. we've heard about how difficult it is to 'deprogram' people that have been taken in by cults.
@mozkitolife5437
8 жыл бұрын
+JZoidberg Agreed. IMO the only difference between organised religion and a cult is the number of people subscribing to them.
@colinscholey
6 жыл бұрын
that is a very narrow minded viewpoint try studying all the religions including the alien annunaki therory and try linda moulton howe if you dare ...she will blow your tinhat right off...the idea that nothing has produced dna is laughable...as is the idea that there is not an alien overlord...look at the face and pyramids on mars...
@bobaldo2339
6 жыл бұрын
Yes and no, Jason. What you think of as "religiosity" is conditioned by your own upbringing, in other words by your own culture. Westerners tend to see all other religions through the distorted lens of the 3 desert religions.
@paulinecoburn181
4 жыл бұрын
Jason Axford Religiosity?
@garymiller3403
4 жыл бұрын
So beautiful presentation!!!!
@bobm4378
4 жыл бұрын
only one thing would improve it, put the slides in a window, so they can be seen all the time.. :)
@MarcoMeerman
6 жыл бұрын
No supernatural deity was needed in this presentation about life.
@brucemulvey9948
5 жыл бұрын
Marco Meerman That’s right. That’s the point after all isn’t it?
@williamgoode9114
4 жыл бұрын
No, but science will, via AI+Net, encouraging better behavior for a varied and sustainable PLANET.
@jamesbaker9923
2 жыл бұрын
I learned a lot from watching this presentation.
@yoyo-jc5qg
3 жыл бұрын
good stuff this clears things up a bit ... so dna is just information like a language, genes are a set of instructions or paragraphs, chromosomes are chapters and a genome is the whole book on a species, nice
@warshipsdd-2142
2 жыл бұрын
Outstanding and informative presentation
@Dr.Scorpio
2 жыл бұрын
Great lecture. Thanks a million. Love your Irish accent ❤️
@kennylong7281
2 жыл бұрын
Human beings have been practicing Artificial Selection for thousands of years. The deliberate mixing, and breeding of selected plants, and animals have given us the food grains, all the fruits vegetables varieties, and all of our farm animals. The power of selective breeding was well known for centuries before Darwin. Gregor Mendel was the first scientist to carry out in depth research on heredity. Once you understand the process of ARTIFICIAL SELECTION, it is a very simple step in the understanding of NATURAL SELECTION.
@vats_chauhan
Жыл бұрын
I m civil engineer but I loved this genetics world quantum world too.
@raresmircea
2 жыл бұрын
Interesting, thanks for these presentations!
@Paul-nr6ws
2 жыл бұрын
Interesting take on balancing nature,
@krisreilly8856
6 жыл бұрын
Genuinely freaked out by the face behind the stairs.
@istvansipos9940
6 жыл бұрын
"this is where the magic begins" - she said this in that dress and I simply could not NOT think about Tinker Bell :- )
@774Rob
10 жыл бұрын
I am terrible at speaking in front of a group and would not wish to criticise but if she slowed it down a bit she would be magic.
@RalphDratman
10 жыл бұрын
She has a lot to communicate in a relatively short time.
@RalphDratman
10 жыл бұрын
FRANCIS FALUDI I agree! In fact, I sent her a message suggesting she make more youtube videos!
@bickleigh3283
10 жыл бұрын
For a lecturer I though her pacing was spot on!
@RalphDratman
10 жыл бұрын
Bick Leigh It was for me, too, but I think people really differ in the rate they prefer. I like to hear a lot in a short period of time -- as long as I can follow what's being said. Others might want more time to digest what's been said.
@timlandscheidt
10 жыл бұрын
FRANCIS FALUDI I'm pretty sure I heard a sigh at the end of the video :-).
@RawHeadRay
2 жыл бұрын
Ahhhhhh, nothings more nourishing after 20 years in USA than an Irish woman talking ,
@iamgreyhorse
2 жыл бұрын
Humans are learning how we were designed, but we don't have enough wisdom to use this knowledge peacefully !
@jbisntme
2 жыл бұрын
It’s just amazing how evolution just happened…. Wow ! Very simple , but complicated…?
@envergrainca2968
2 жыл бұрын
Explain the beginning of life and elaborate further
@philcoombes2538
2 жыл бұрын
Do you speak English with a foreign accent, & the speech-to-text app is picking that up...?
@strangelimey
10 жыл бұрын
Y'all need to stop apologizing to creationists. They have nothing. We have the universe.
@RalphDratman
10 жыл бұрын
I do apologize to creationists! I am sorry the education system failed so badly in your community. I am sorry you don't know enough about the world to realize that you cannot just nullify facts and deductions that have been checked by teams of scientists in thousands of labs all around the world. I am sorry you are missing out on the fantastic story of the powerful discoveries our species has made about nature.
@strangelimey
10 жыл бұрын
Ralph Dratman Erm, that was my point. I do know enough to know that dogma from a book written by iron age desert wanderers has nothing on hundreds of years of research and experimentation.
@RalphDratman
10 жыл бұрын
Michael Stone Each of my three paragraphs was addressed to the creationists, not to you. For example, in the first paragraph I meant "I am sorry the educational system has failed you creationists in your communities." My post was a sort of joke, just kidding around. I completely agree with you.
@MrWdh2
10 жыл бұрын
Michael Stone I'm not a "creationist" and I fully agree with you about dogma, and that we have to very careful about what we believe, especially if it seems to be supported by mathematical formulae and computer modelling, which we all too readily regard as infallible. Even science itself is not immune to self deception and error as Richard Milton so eloquently documents in his book, "Alternative Science". So, it would seem that our faith in what science has so far revealed to us is every bit as unshakable as the faith of those desert wanderers you spoke of. In fact it's even more unshakable, because we believe we have incontrovertible proof - at least until we're proven wrong once again. It's because of its rigidity that dogma is always wrong, whether it be religious or scientific. The textbooks are constantly being changed and updated, and what was "true" yesterday is no longer "true" today. That's just the nature of scientific knowledge. I believe that science offers us a wonderful tool for understanding the world around us. But, when science is wrong, it's every bit as wrong as any other belief system. To it's credit, science is a self-correcting belief system, but that tells us we should never be too sure of what we think we know. We have to be careful not to turn the scientific beliefs of today into the dogma of tomorrow.
@dante224real1
6 жыл бұрын
i am sorry you were created to begin with.
@nelsongonzalez4533
4 жыл бұрын
How much further or how far can we evolve? How devolution? Science and technology can answer that question. Right?
@crimsonstarr6122
3 жыл бұрын
Technically, we're always evolving. There are areas in our genome right now that are undergoing selection.
@rozemarijnjongeneel3875
5 жыл бұрын
This was super interesting!!
@baraskparas9559
2 жыл бұрын
Gene copy number is only one of over 30 different factors that feed back on DNA to control gene expression.
@BUD7H357UD
10 жыл бұрын
this should be a ted talk
@ChristopherRucinski
10 жыл бұрын
***** 30 minutes shorter and getting a much larger audience? Yes, thanks. Heck, creating a 5 minute "Executive Summary" would be an amazing idea, and a great scientific nugget of information.
@VICARI0S
10 жыл бұрын
Christopher Rucinski Nope. This is fine as it is. No need to shorten it.
@ChristopherRucinski
10 жыл бұрын
Nathan Yeung I agree with you, but a shorter one that will allow more people to see it.and.understand would be cool. Trust me, I love this video and think it has great content. If you ever read a paper you will understand how powerful the executive summary is in understanding what the whole paper is about.
@BertVerhelst
6 жыл бұрын
I wonder if the analysis of the DNA of babies that were miscarriages or were born dead could identify the genes that cause the plane to "crash". Although it is probably very hard to get consent for those cases.
@chriswinchell1570
2 жыл бұрын
Most of the disorders are numerical. There are very few disorders where the numbers are more or less than the 46 where the fetus is viable.
@HorseJouster
10 жыл бұрын
Brilliant lecture but I kept getting distracted by the gorgeous presenter 🍀
@alangarland8571
6 жыл бұрын
Well yes it does distract a bit from the chemical properties of Globins. Very good talk though, she has the gift of the gab.
@blastulae
6 жыл бұрын
Have to agree. I'd urge her to wear a bit longer of a dress at next outing.
@jasomara
6 жыл бұрын
keep it in your pants
@terrybuchanan1204
5 жыл бұрын
that's genetics
@dhiashanshal2461
5 жыл бұрын
To every body! Please help Why is evolution? How evolution happens ? is it a kind of quantum process? If so why? Can metal and nonmetal evolute ? Why not?!
@mdb1239
3 жыл бұрын
Can we say complex processing/timing/2-D & 3-D folding must all align to generate a protein. And all this works in and around the cell due the very very very very special properties of water from it's subatomic properties to it's surprising macroscopic properties --- all existing so that life process can just exist.
@mightyfinejonboy
10 жыл бұрын
sorry, i only clicked because i saw a fox......
@MattSiegel
10 жыл бұрын
oh behave
@solapowsj25
3 жыл бұрын
Good presentation. ATCG.
@anjuk6255
3 жыл бұрын
Wow a different approach..Understanding biology is like investigating a crime; everything that has happened can be connected with different approaches.
@moniquealicia9508
3 жыл бұрын
But she is wel spoken
2 жыл бұрын
How many Parent-Child-Twins are there?
@dashnarayana
5 жыл бұрын
very elegant and uptodate beautiful presentation.
@BanyaiTheScienceGuy
10 жыл бұрын
This should be required viewing for everyone. Things I suspected while studying biology, but now we have actual evidence. Amazing!!!
@aoifemclysaght3586
10 жыл бұрын
Glad you enjoyed it!
@BanyaiTheScienceGuy
10 жыл бұрын
Glad you presented it!
@gsilcoful
5 жыл бұрын
Thank you.
@pahkk
2 жыл бұрын
I love her passionate speech! Even with her sporadic panting, I feel humane with her.
@travisfitzwater8093
2 жыл бұрын
It has not escaped my notice, she's got the best genes to create a very adept Broca's Area and the facial muscular skeleton to produce an engaging mannerism. That's the kind of person you'll want to "copy genes" with, you know what I mean.?
@TSulemanW
2 жыл бұрын
what is couse of evolution
@yukhyx4096
4 жыл бұрын
A beautiful presentation. Evolution and creation are not mutually exclusive. In fact the beauty in the genetics could only have evolved as a result of a purposeful creation.
@allwinaugustine
4 жыл бұрын
Why protiens are called so even though they differ in functions? Anything common in all protiens?
@MyYTwatcher
4 жыл бұрын
Proteins is a general term for organic molecules which are built from aminoacids.There are 20 aminoacids and if they combine and make long chains such chain is called a protein.
@climbeverest
7 жыл бұрын
Great stuff
@thedailydao
2 жыл бұрын
30:30 The use of evolutionary patterns to infer meaning is the same means I knew that genetic evolution made sense before I knew why? Oh my! I NEVER
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