Don't miss my 50 hematology 💉 cases, limited availability, go to www.patreon.com/medicosis/
@hameedkhan-qe1kd
5 жыл бұрын
where is microbiology.cardio-diseases,respiratory disease
@MedicosisPerfectionalis
5 жыл бұрын
On their way
@gratitude5740
5 жыл бұрын
Medicosis Perfectionalis Where can I get COX2? I’m going to have a surgery in October. Don’t want to take NSAIDS . Thank you you !
@alexisernesto3184
3 жыл бұрын
i guess Im kind of off topic but do anybody know of a good place to watch newly released movies online?
@zyairenixon1498
3 жыл бұрын
@Alexis Ernesto Lately I have been using FlixZone. Just google for it =)
@ThePrsBee
2 жыл бұрын
Time will come when education will b like this....its actually interesting, its simple, very logical, fun to watch, keeps attention and without noticing u just learned everything till the ending of the video!! Great stuff, Thanks man, You are really awesome!!.... hitting something that 99,9% of the professors r unable to do....
@MedicosisPerfectionalis
2 жыл бұрын
Thank you ☺️
@nal9345
4 жыл бұрын
i didn't know that i can laugh so hard watching a pharmacology video....
@MedicosisPerfectionalis
4 жыл бұрын
😂😂 Learning should be fun!
@luiginews73
2 жыл бұрын
Me neither!!!!!! 🥰🥰🥰🥰🤣🤣🤣🤣🤣🤣🤣
@ronakroshan7878
6 ай бұрын
An absolute boon to us med students. My professor taught this once and took an hour for this. I can revise the same pathway in less than 15 mins, with diagrams, mnemonics, concepts and clinical correlations as well. Thank you, good sir!!!
@MedicosisPerfectionalis
6 ай бұрын
I am honored! Kindly help me by sharing my videos with others!
@suyogkhanal8382
3 жыл бұрын
Damn, this video is funnier than most of the stand up comedies🤣
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much 😊
@bayan8285
Жыл бұрын
You made pharmacology fun to me !! Thanks
@MedicosisPerfectionalis
Жыл бұрын
I'm so glad!
@thelmataonga5211
4 жыл бұрын
You're definitely the best 😩😩how can one ever forget the concept 🥰🥰
@MedicosisPerfectionalis
4 жыл бұрын
Thanks a million! I am honored!
@humairaakter739
5 ай бұрын
I'll never understand how you can teach complex things, that even professors find difficult, so easily. Thank you so much sirrr❤
@ayda.mohammed
Жыл бұрын
Hi sir 🥰 you are saving me every time I have an exam.. Sending gratitude and love for you 🥰🥰🥰 You are a great human being
@MedicosisPerfectionalis
Жыл бұрын
Thank you so much 😊 I appreciate you!
@elsagrace3893
2 жыл бұрын
These are the best videos! Man, I am just a regular person with no medical education just an interest. You make it understandable and entertaining.
@MedicosisPerfectionalis
2 жыл бұрын
Thank you 😊
@carlydew9891
4 жыл бұрын
the BEST teacher ever, I wish you could teach all of my lectures.... these videos are pure gold.
@MedicosisPerfectionalis
4 жыл бұрын
Thanks a million, dear! I am speechless. Can you please help me by sharing?
@carlydew9891
4 жыл бұрын
@@MedicosisPerfectionalis shared with my classmates!!
@islamsaleh4697
4 жыл бұрын
After 2 days of digging in the COX mode of action, none of the article was easy to read....found this video that made my life easy...Amazing job done boy
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊
@islamsaleh4697
4 жыл бұрын
@@MedicosisPerfectionalis I have only one question if you please. In 5:39 you said, now you know why inhaled steroids are used to treat asthmatics. This is because they block the pathway leading to production of Thromboxane A2 and so no vasoconstriction?
@MedicosisPerfectionalis
4 жыл бұрын
No, it’s because inhaled steroids block the PLA2 and therefore decrease the level of arachidonic acid. This will, subsequently, decrease the level of leukotriens which make the life of an asthma patient hell!
@islamsaleh4697
4 жыл бұрын
Medicosis Perfectionalis u r awesome..thanks a lot
@stephenb9843
3 жыл бұрын
Bro love the video, the sarcasm is great. It's funny, the way you talk is the same way I talk to myself when I'm studying. Thanks for making this!
@MedicosisPerfectionalis
3 жыл бұрын
You're very welcome 😊
@adjoaacquaye3846
Жыл бұрын
You make it a point to respond to every comment. You’re a great teacher❤
@MedicosisPerfectionalis
Жыл бұрын
I am honored!
@lindaz5340
3 жыл бұрын
This video is pure gold. Funny and informative!! Concepts well explained
@yusrahassan2363
Жыл бұрын
Thank u thank u thank u. Honestly love people who are make sure to help others by education and other things they can offer the society with
@MedicosisPerfectionalis
Жыл бұрын
Thank you 🙏
@salaheddinefilali2824
Жыл бұрын
spent hours looking up this stuff online, this video couldnt have been more helpful !!!
@alyelize
3 жыл бұрын
Sometimes I think you know me better than I do, because as soon as I have a question, you immediately answer it!
@MedicosisPerfectionalis
3 жыл бұрын
Haha 😂
@SamJewel
3 жыл бұрын
great presentation thank you from a non academic studying herbs!
@MedicosisPerfectionalis
3 жыл бұрын
Thank you!
@ofdelia
3 жыл бұрын
I never comment on KZitem videos, but your channel is one of the best things I've ever found on the Internet. Everything is so well explained and you're so damn funny. A huuuge thank you ❤️
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much 😊 I am honored!
@Milkbop
3 ай бұрын
El mejor video de quimica que he visto sobre la ciclooxigenasa :D
@MedicosisPerfectionalis
3 ай бұрын
🙏🙏🙏
@thatguy-lg9vn
3 жыл бұрын
i really love your sarcasm and funny jokes, this is my first video and i cant help but to subscribe. thank you very much !!
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much 😊
@CiaraWithLinzixD
4 жыл бұрын
I didn't know when clicking on this video I'd laugh, let alone how much I did. Amazing work ahahhaa
When you linked it to real clinical scenarios, it felt like it clicked! Thank you! Also, I am from Australia and I am worried there are differences in the naming of certain things. Should I be worried about any differences that you know of?
@MedicosisPerfectionalis
4 жыл бұрын
Hey 👋 Emily...Thank you so much for your kind words...Brand names differ between countries, but what really helps is knowing the generic name by heart.
@kendramleko8740
4 жыл бұрын
oh how I wish you were my pharmacology professor. This makes so much more sense now!
@MedicosisPerfectionalis
4 жыл бұрын
Awesome 👏
@jojoe69
3 жыл бұрын
man, I fucking love you and your sense of humor
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much!
@chlooeydeschanel5159
3 жыл бұрын
I'm subscribing purely for your laugh. The personality in this video makes me actually enjoy pharmacology
@MedicosisPerfectionalis
3 жыл бұрын
I am honored! Thank you 🙏
@robertcoyle1532
4 жыл бұрын
Informative and humorous.... as always... a winning combo.
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊 Can you please help me by sharing?
@phillipnrup4085
2 жыл бұрын
Awesome video. I am currently writing an article about this subject, and it was really informative and entertaining. Keep it up.
@MedicosisPerfectionalis
2 жыл бұрын
Thank you 🙏
@leadr5519
4 жыл бұрын
I found you just before our exam! I feel so lucky. Sending love! Thank you for the fun-niest learning💚
@MedicosisPerfectionalis
4 жыл бұрын
Thanks a million, dear :) I truly appreciate it. If you have time, can you please help me by sharing?
@Staytruebeing
5 жыл бұрын
U got a nice way of teaching...keep it up...good job man...i like ur style
@MedicosisPerfectionalis
5 жыл бұрын
Thanks a million!
@mms7146
3 жыл бұрын
you are better than my uni teacher
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much ☺️
@musicbeachdance
2 жыл бұрын
I love the prostacyclins keep the blood "cyclin" that helps me actually recall PGI2 function!
@MedicosisPerfectionalis
2 жыл бұрын
Thank you 😊
@esthermwangangi8930
2 жыл бұрын
Very creative ways of nomenclature,doctors are geniuses...🤣🤣🤣
@MedicosisPerfectionalis
2 жыл бұрын
Haha 😂
@bismarck5503
4 жыл бұрын
thank you u got a new follower , im pharmacy student and this is way better thanhow my professor explain
@MedicosisPerfectionalis
4 жыл бұрын
Thanks 😊 Can you please help me by sharing it with your colleagues?
@nataliezavada9424
4 жыл бұрын
You are absolutely the best at explaining things in a way I understand! And you're so funny, my 14 year old watches you with me just to hear you're jokes
@Itsmempps
Жыл бұрын
Thank you very much I always love watching your video Your video help me alot ❤
@MedicosisPerfectionalis
Жыл бұрын
I am honored, Mary!
@alvinchin7856
4 жыл бұрын
first video i saw, you already earned my loyal subscription
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊
@hamnaiqbal230
Жыл бұрын
what an explanation man😍😍😍.....thank you for making it easier and funny👍🏻👍🏻
@MedicosisPerfectionalis
Жыл бұрын
My pleasure 😇
@Pree__
4 ай бұрын
iv never heard an into this insanely cooooll
@MedicosisPerfectionalis
4 ай бұрын
Thank you so much!
@canvas2327
2 жыл бұрын
Sir u have great sense of humor
@MedicosisPerfectionalis
2 жыл бұрын
Thank you ☺️
@philanthropist723
4 жыл бұрын
I was not bored for a single miN lol thanku! really helpful
@MedicosisPerfectionalis
4 жыл бұрын
Wow 🤩 Thank you so much 😊
@creativerick7458
2 жыл бұрын
Thanks for this, I'm working on a article. This gave me a great insight.
@MedicosisPerfectionalis
2 жыл бұрын
Yay 😃
@rokiaamr4312
2 жыл бұрын
Thanks alot for your easy simple entertaining Explanation 💜💜.. really appreciate it !! You are awesome
@MedicosisPerfectionalis
2 жыл бұрын
Thank you 😊
@563051
4 жыл бұрын
It was great. So simple and easy to remember way of teaching
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊
@563051
4 жыл бұрын
@@MedicosisPerfectionalis may you make a lecture about antipsychotics?
@-itsnoora-5533
4 жыл бұрын
thank you! you just saved my LIFE
@MedicosisPerfectionalis
4 жыл бұрын
My pleasure 😇
@ghassanauf8103
4 жыл бұрын
You are amazing , I’m in love with your lectures
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊 I am honored!
@johnpavlic3292
5 жыл бұрын
THIS HELPED ME SO MUCH!
@MedicosisPerfectionalis
5 жыл бұрын
Awesome 👏
@Talifania
3 жыл бұрын
YOU ARE FREAKIN FUNNY. I love it. Learned so much.
@MedicosisPerfectionalis
3 жыл бұрын
Thank you so much 😊
@harrysmisty9165
4 жыл бұрын
Stupid stuff you learnt in physiology 😂 you made my day , i enjoyed this lesson , thank you
@qixiantang1311
2 жыл бұрын
great video...just curious about how does the NSAID drug inhibits the cyclocygenase? like the functional groups present within the binding site etc....
@unknownbeliever4660
5 жыл бұрын
I wish i could shake my hand with you..just awesome man., 💜💜💜💜
@MedicosisPerfectionalis
5 жыл бұрын
🤝🤝🤝
@unknownbeliever4660
5 жыл бұрын
@@MedicosisPerfectionalis 😂😂 handshake in online is like this
@MedicosisPerfectionalis
4 жыл бұрын
😁😁
@unknownbeliever4660
4 жыл бұрын
@@MedicosisPerfectionalis 💚💙💚💙
@MedicosisPerfectionalis
4 жыл бұрын
👍😍😍
@adfarshafi1884
4 жыл бұрын
Thank you ❤😘
@MedicosisPerfectionalis
4 жыл бұрын
My pleasure 😇
@KeaJei
5 жыл бұрын
Got curious about cox 1 and cox 2 because celebrex only inhibits the latter and I'm wondering why I'm still in pain compared from when I took ibuprofen before getting prescribed celebrex. I have otitis externa. From what I understood, I shouldn't be in pain. This is coming from a non-pharmacy student. Thank you very much by the way for having this lecture free for everyone to learn. :)
@MedicosisPerfectionalis
5 жыл бұрын
My pleasure 😇 I am sorry for your pain, but I really don’t know...Please talk to your doctor.
Amazing Video, Thank You for sharing your Knowledge with us.
@milendawit5448
5 жыл бұрын
THANK YOU VERY MUCH! YOU ARE JUST AMAZING!!
@MedicosisPerfectionalis
5 жыл бұрын
Thanks a million 😎
@EylulTurksever
Жыл бұрын
One might have tought: maybe if you inhibit COX1, since COX2 still works and can't make TXA2, it can make more PGI2 when not racing against COX1 for PGH2 thus decreasing the risk of clotting more than non-selective COX inhibitors?
@stigmine3
11 ай бұрын
Thankyou so much🙌
@MedicosisPerfectionalis
11 ай бұрын
My pleasure!
@anthony2k81
4 жыл бұрын
The best lectures!
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊
@m.m.m.c.a.k.e
2 жыл бұрын
You are great! I am beside myself angry with uneducated nurses shaming me for managing pain after a surgery without NSAID’s (asthmatic). I don’t know why in the hell I have to do all of this research myself as a patient. I have learned a lot but this is aggravating. Anesthesiologist understands it. What do I tell these people? Please help
@MedicosisPerfectionalis
2 жыл бұрын
Thank you 🙏 I appreciate your comment! I really admire your perseverance and the fact that you are doing all of this research even though you’re not a doctor! Hats off to you!
@m.m.m.c.a.k.e
2 жыл бұрын
@@MedicosisPerfectionalis well my friend, I’ve always had interest in the medical field…. being a seasoned IT veteran, many of those whom which I’ve helped have called me a doctor anyway, lol. Being an analytical thinker to begin with, they have some alignment. Anyway if anybody would be kind enough to provide their two cents I would love to hear it. Obviously it’s not going to be taken as any sort of medical advice I promise! More or less,, direction,, would be nice or references to material that I can study. Just trying to feel better as all. And I’m in such a small group of people apparently. Asthma exacerbation caused by classical NSAID’s with persistent nasal polyps and contact dermatologist. I’ve been called lucky in the past by several people. Evidently as my life continues I realize I am always gaining on that forefront LOL…
@dorothysam3676
4 жыл бұрын
I really love this teaching yo perfect 👍🏼
@MedicosisPerfectionalis
4 жыл бұрын
Thanks a million!
@musikaaffection8570
9 ай бұрын
Thank you soo much sir ❤
@MedicosisPerfectionalis
9 ай бұрын
Most welcome!
@maximebarry4069
Жыл бұрын
I couldn't thank you enough !
@anikhalder187
5 жыл бұрын
Very helpful and fun in learning.
@MedicosisPerfectionalis
5 жыл бұрын
Thanks a ton!
@SB-po7un
2 жыл бұрын
You are amazing. Thank you for your videos♡♡♡
@MedicosisPerfectionalis
2 жыл бұрын
My pleasure 😇
@Teezar22
3 жыл бұрын
Can't thank you enough for this content.
@MedicosisPerfectionalis
3 жыл бұрын
My pleasure 😇
@nooralebarhim8965
5 жыл бұрын
YOU ARE AMAAAAAAAAAZING...THANK YOOOOOU
@MedicosisPerfectionalis
5 жыл бұрын
My pleasure 😇
@shadawnhenderson9186
3 жыл бұрын
Probably the funniest video I have ever seen.... lol
@MedicosisPerfectionalis
3 жыл бұрын
Thank you 🙏
@chineduanieke540
4 жыл бұрын
Great teaching..... Bless up
@MedicosisPerfectionalis
4 жыл бұрын
Thanks 🙏 Can you please help me by sharing?
@lakshmij2989
Жыл бұрын
Hello sir, can you please do a general pharmacology videos
@MedicosisPerfectionalis
Жыл бұрын
I have an entire series of videos (course) about general pharmacology here: www.medicosisperfectionalis.com/products/p/general-pharmacology-course/
@dandrew3390
3 жыл бұрын
Hi, I love your videos. However I don't think the vignettes at the end are accurate and may confuse medical students here as the pain management suggested is only viable in a utopic world. Experience teaches us that this is not viable. 1) COX-2 inhibitors are frequently used for arthritic pain. But we must remember that patients with arthritis tend to have cardiovascular issues so these should be used with extreme caution. COX2 inhibitors may be more viable in younger athletes with joint pain. 2) COX-2 inhibitors are to be avoided in the post-operative phase because they may augment the stress response to surgery, possible even putting the patient in DIC. 3) I honestly have no idea what this is (I'm just a stupid surgeon) and will not dwell on this. Apart from that, keep up the really good videos!
@Dudu-if4jo
3 жыл бұрын
Ahahha never enjoyed studying before thank you
@MedicosisPerfectionalis
3 жыл бұрын
My pleasure 😇
@thamisanqadeputy7695
2 жыл бұрын
My GOAT🐐
@MedicosisPerfectionalis
2 жыл бұрын
Thank you so much!
@jamiek6471
5 жыл бұрын
precious explanation1
@MedicosisPerfectionalis
5 жыл бұрын
Thanks 🙏
@nutricionveritas5352
3 жыл бұрын
This is amazing, thank you so much!
@MedicosisPerfectionalis
3 жыл бұрын
My pleasure 😇
@martinanuneva5876
Жыл бұрын
should be called sassy science. loved it tho
@MedicosisPerfectionalis
Жыл бұрын
😂
@bruryrosally
4 жыл бұрын
2:31 in the name of God The most merciful بسم الله الرحمن الرحيم
@pharmacist2125
3 жыл бұрын
💜
@accountnew6474
5 жыл бұрын
Why was only Rofecoxib removed and not other COX 2 selective NSAIDs? Don't they all increase the risk of blood clotting because like you said at 9:44?
@MedicosisPerfectionalis
5 жыл бұрын
Theoretically you are correct, but in the real world, there seem to be a difference.
@TheMrLokuaiya
4 жыл бұрын
Brilliant video!!
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊 Can you please help me by sharing?
@jakeparelta7846
4 жыл бұрын
You are very much inspiring.i want to be cool like u
@MedicosisPerfectionalis
4 жыл бұрын
I am humbled ☺️
@CapesReels
3 жыл бұрын
Its fun to watch these videos on 1.5X Speed. The Jokes land very well
@MedicosisPerfectionalis
3 жыл бұрын
Haha 😂
@lilianaproenca6064
5 ай бұрын
Hello! I love this video, thank you! I would like to ask about the PGI2 - prostacyclin, its COX-1 and COX-2? At your "game" COX 2 OR COX 1 you left PGI2 out :)
@nurnadhirah6152
4 жыл бұрын
Thanks for the video. I love it. 🙆🏻♀️❤️
@MedicosisPerfectionalis
4 жыл бұрын
My pleasure 😇
@mennaashraf4410
4 жыл бұрын
Amazing but i have one question so cox-1 is responsible for stomach protection by which prostaglandins is it PGE2 but its also responsible for pain
@aceo_o2295
5 ай бұрын
Thank you so so much
@hungryasian9883
5 жыл бұрын
hello, have an pharmacology text book "pharmacology for health professionals 5th ed, by B, Byrant & K, Knights, and it says that it is PGI2 with COX1 inhibition that causes gastric ulcers, not Thromboxane A2 and now im confused to know which is right. Could you please be able to explain why the text book may be saying this and why you have said otherwise? Thank you :)
@MedicosisPerfectionalis
5 жыл бұрын
I never said that inhibition of thromboxane A2 causes gastric ulcers.
@hungryasian9883
5 жыл бұрын
@@MedicosisPerfectionalisoops my bad, then what causes gastric ulcers more specifically other than just saying COX 1? I just want to learn thank you :)
@MedicosisPerfectionalis
5 жыл бұрын
There are some prostaglandins that protect the stomach...These prostaglandins are produced thanks to COX-1...When a drug inhibits COX-1 and COX-2, the protective mechanism is destroyed. However, when a drug selectively inhibits COX-2 only, the stomach is in good shape because COX-1 is uninhibited...Hope it helps!
@hungryasian9883
5 жыл бұрын
@@MedicosisPerfectionalis thank you very much :)
@MedicosisPerfectionalis
5 жыл бұрын
My pleasure 😇
@sandmistbreeze
5 жыл бұрын
awesome video .got solid concepts!
@MedicosisPerfectionalis
5 жыл бұрын
Great 👍
@MA-dd9dd
3 жыл бұрын
You’re the BEST
@MedicosisPerfectionalis
3 жыл бұрын
Thank you 🙏
@rukaiyapasha1209
4 жыл бұрын
WOW... Just WOW :)
@MedicosisPerfectionalis
4 жыл бұрын
Thank you so much 😊
@wtficantgetausername
3 жыл бұрын
jeeeez that was solid
@vipereshon7041
2 жыл бұрын
That was really gud , thank you
@MedicosisPerfectionalis
2 жыл бұрын
My pleasure 😇
@TheRealMorgs41
2 жыл бұрын
So does this pathway, work differently in different cells. So the membrane phospholipids of platelets dont produce leukotrines do they. So its not really at multiple choice pathway but a single choice depending on what cell you are?
@raspberry765
4 жыл бұрын
Thank you for the video! Which one makes PGI - COX1 or COX2?
@MedicosisPerfectionalis
4 жыл бұрын
PGI2 is by COX-2...Mnemonic: 2 by 2
@aishakernazi9776
4 жыл бұрын
جزاكم الله خيرا
@MedicosisPerfectionalis
4 жыл бұрын
You too
@indethbed2546
2 жыл бұрын
if the cell membrane is 55% protein and 42% lipid.. why isn't it called lipoprotein bilayer?
@sarakulsoom401
4 жыл бұрын
Can u plz answer why diclofenac sodium is enteric coated while potassium is not?
@MedicosisPerfectionalis
4 жыл бұрын
It’s just the manufacturing process. They simply succeeded in coating the diclofenac sodium.
@fatemaatia4385
5 жыл бұрын
Soo professional 👌😎
@MedicosisPerfectionalis
5 жыл бұрын
Thanks, dear :) Please share my videos with others...It really helps!
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