"what's up with this marker?" fav part of the video. you're a superstar
@nusratjahan5976
6 жыл бұрын
He sounded so different when he said that. :o
@katelynwilliams6930
5 жыл бұрын
IKR!!! first time hearing him speak like that in all the lectures i ever watched from him
@turki2788
5 жыл бұрын
@@nusratjahan5976 Trust me he is not a human, he is a robot I am sure you will figure out this later
@issaam_p6681
4 жыл бұрын
He was bout to beat the shit out of that marker
@mareknagy4221
5 жыл бұрын
How he got equation 5 final form: A. [ES] = ( ([E]total - [ES]) [S] ) /Km B. [ES] = ([E]total*[S] - [ES][S]) /Km C. [ES]*km = [E]total*[S] - [ES][S] D. [ES]km + [ES][S] = [E]total*[S] E. [ES]*(km + [S]) = [E]total*[S] F. [ES] = [E]total*[S] / (km + [S])
@mauliksadhu8963
5 жыл бұрын
Thank you ☺👍
@elisabettapampalone918
4 жыл бұрын
thank you!!
@Jordanadean
4 жыл бұрын
You're the real MVP
@mohammedahmedjalloh531
4 жыл бұрын
Thanks for making this clarity because i also observe the same haha.... B/w 4 and 5 was a bit fuggy.... but you did it
@silvioletitiya1561
4 жыл бұрын
Thank you so much
@abraianmiller9445
7 жыл бұрын
Y'all can't get my mans a decent marker while he up here preachin?
@mizzannie001
6 жыл бұрын
lmaooo
@momenakhatoon5996
3 жыл бұрын
I just wanted to say that I appreciate EVERYTHING you're doing. Simply 10x more than what any professor has ever done, and they're the ones getting my money. You go into depth, simplify everything perfectly that makes it easier to understand!
@jonBrazilian
8 жыл бұрын
Watching you from Brazil and I am so impressed at how great a professor you are. Your lectures are just excellent! Great explanations. So clear and you go over the right details that will clarify the most difficult parts when understanding these complex concepts. We cannot thank you enough :)
@angelaliu1274
26 күн бұрын
I cannot express my gratitude enough for you generous share of your knowledge. True Saint ❤
@eiklinoh9402
8 жыл бұрын
i thank God for your existence :)
@emiderkx7299
7 жыл бұрын
I agree on a spiritual level with you, my friend
@issaabujeries2912
4 жыл бұрын
You are a blessing to Pre-Meds! No words to describe how phenomenal you are.
@njymer1019
2 жыл бұрын
been following your lectures since my third undergraduate year, good news, i passed my biochemistry exam...God bless you
@FullCodedAlchemist
Жыл бұрын
thank you for the detailed, thorough, and simple explanation. wasn't a fan of how most people explaining this equation and the textbook giving out the equation and providing only vague, surface-level information and expect you to master everything. i appreciate you taking the time to work through the steps and connecting them.
@ericmuema7968
2 жыл бұрын
well explained. Thank you
@user-km8df4pe7x
5 жыл бұрын
Your lecture is much more easy and precise than that of my professor.
@dinoismaili5736
4 жыл бұрын
As far as I can tell, everything up until equation 8 revolves around whats happening at the beginning of the reaction, when time is close to 0. Så equation 8 explains how the velocity of the reaction stands in relation to the concentration of S but only at the beginning. It makes perfect sense, but I just don't grasp how the concentration of S stands in relation to the middle velocity, its either beginning or Vmax. Why would you plug in Vmax with Vo? Thats where I loose it
@vincentrodrigo1414
4 жыл бұрын
#5 equation simplified: Looking at Michaelis Constant, it's basically saying [E] [S] / [ES] = Km. Cross multiple it which will become [ES] Km = [E] [S]. then divide Km on both sides to get [ES] = [E][S] / Km
@youknowthat17
7 жыл бұрын
I don't understand how number 5 gets to the next formula (on the same line). How do you get Km + [S] :(
@hughtiff
6 жыл бұрын
Yeah, I don't get how he got equation 5 too
@meetalijoshi3232
5 жыл бұрын
He just solved the equation for [ES] mathematically. If you bring the [ES] to the left side of the equation then you will get the result.
@vincentrodrigo1414
4 жыл бұрын
It's just simple algebra. Looking at Michaelis Constant, it's basically saying [E] [S] / [ES] = Km. Cross multiple it which will become [ES] Km = [E] [S]. then divide Km on both sides to get [ES] = [E][S] / Km
@anast456
Жыл бұрын
Thank you so much.your effort is priceless ❤️❤️❤️
@annetduivenvoorden343
8 жыл бұрын
Around 4.15 you describe that you have to remove the ES from the right side. But how do you this and [S] also appears next to Km?
@jesusdanielestradaalba8073
8 жыл бұрын
+Annet Duivenvoorden I have the same question
@wumz4528
8 жыл бұрын
+Jesús Daniel Estrada Alba same question how sway??!
@agustinabasso3020
7 жыл бұрын
You just replace it by the new equation of ES
@techheaven007
7 жыл бұрын
we call this thing 'jugaar' in India xD!! that means sometimes you have to do certain things to pass your exam that you don't know 😂😂😂😂😂😂
@ChrisRocker25
7 жыл бұрын
Annet Duivenvoorden Hi Annet, I will try to help you. You have to put [E] value = [E]total - [ES] in the ecuation: K1 [E][S] = (k-1 + k2) [ES]; so you will obtain this new ecuation: k1([E]total - [ES])([S]) = (k-1 + k2) [ES] then you can multiply and will obtain this new ecuation: k1([E total][S]) - k1 ([ES][S]) = (k-1 + k2) [ES] now you can group the therms with [ES], and you will obtain this: k1([E total][S])= (k-1 + k2) [ES] + k1 ([ES][S]); so you can group again by the factor [ES]: k1([E total][S]) = (k-1 + k2 +k1[S])[ES]. so: [ES] = k1([E total][S]) / (k-1 + k2 +k1[S]) and now you simply the equation: [ES] = ([E total][S]) / ([S]) + ((k-1 + k2))/(k1) you also know the meaning of this: ((k-1 + k2))/(k1) = km so you can obtain the final equation: [ES] = ([E total][S]) / ([S]) + km Have a good night.
@Starcell170
8 жыл бұрын
Thanks! I have thought "why V_0 can be equal V?", but now i know it is a poor qeustion. finally, I have just one qeustion; why ES slaedy-static condition is reasonable?
@anonymous672
8 жыл бұрын
you are awsome ! genius I say! thank you so much.. and please post more videos you are a great teacher!
@CHBSAAmnaShahid
2 жыл бұрын
Thank you so much
@rodrigohuallanca662
Жыл бұрын
Magnificent
@azeeza3076
8 жыл бұрын
you are awesomeeeeeeee
@anmolsudan7321
7 жыл бұрын
Great Lessons very Useful thanka
@deede1
4 жыл бұрын
it should be 9 being plugged into 8. also the Vmax=K2(Et) that can be an easy replacement, without solving it because of it variable replacement.
@akashpanda8668
7 жыл бұрын
you are awesome sir plz describe the phase equilibrium for us . If u will b wid us then we can easily understand anything keep up going
@junczhang
8 жыл бұрын
thank you!! very nice explanation
@merradimanel8985
8 жыл бұрын
Hello Mr.Andrey i have a question if all this reaction occu in steady conditions how can the substarte concentration start from the zero how can Michealis use the brigges theory to obtain taht equation in time where susbtarte concentrations are not the same
@saurabhyadav2541
3 жыл бұрын
Thank u sir amazing ....
@Microbiologist2023
4 жыл бұрын
Even we have all active sites occupied and V reaches Vmax, the equation turns in nonsense. Doesn't it?
@Angel28187
5 жыл бұрын
You’re amazing!!!!!
@HZAexNB
5 жыл бұрын
How do you cancel out k2 in the last equation?
@sanahameed9970
5 жыл бұрын
While putting equation 9 into 8 , k2 divides by k2 as (k2/k2) ,so get cancel.
@carrotcake3368
4 жыл бұрын
Thank you
@SoniaDiversion
7 жыл бұрын
Amazing! thank you
@souravdalapati.6270
6 жыл бұрын
Thank you.
@Sam-bh1zb
2 жыл бұрын
someone give my bachelors degree to this guy, he practically gave it to me.
@tharunk3451
4 жыл бұрын
Good work😊
@priyayeole379
5 жыл бұрын
thank you sir.
@purvanshivakil2531
7 жыл бұрын
Thank you !!
@megerzz16
6 жыл бұрын
praise you
@poojashinde2563
5 жыл бұрын
How have u solved the reaction for (ES) 5 step??
@wardahiftekhar5175
9 жыл бұрын
thank u so much
@felipeignaciogonzalezorden2952
5 жыл бұрын
Just simply awesome explanation
@toquell7386
Жыл бұрын
This video is replacing my professor right now.
@amitkumarsingh57
5 жыл бұрын
I am confused from step 5 where he mentioned plug them into 5. can some one help me.
@vincentrodrigo1414
4 жыл бұрын
It's just simple algebra. Looking at Michaelis Constant, it's basically saying [E] [S] / [ES] = Km. Cross multiple it which will become [ES] Km = [E] [S]. then divide Km on both sides to get [ES] = [E][S] / Km
@Microbiologist2023
4 жыл бұрын
I mean the equation after the 7th equation
@irfanullah3205
5 жыл бұрын
MAy Allah live long you
@khanyisonqwili8131
8 жыл бұрын
Wow No dislikes...
@TurdFurgeson571
2 жыл бұрын
On these kinds of videos people always say things like, "This was so much clearer than my professor!" We must be aware that out professors laid the foundation upon which we were able to place AKL's information, which gave us clarity. Imagine how effective your prof could be if you implemented this concept by studying ahead.
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