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Time Stamps:
0:08 Introduction / Explanation of what DHT itch is.
1:29 DHT and the skin at a glance
1:59 DHT Itch: Does it exist?
2:20 DHT Hair health
3:11 DHT and sebaceous glands
4:00 DHT causes over production of sebum
4:22 The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: A Outpatient-Based Study
5:00 Seborrheic Dermatitis linked to Acne and Androgenetic Alopecia
5:19 Connection between AGA and Seborrheic Dermatitis
5:40 Androgenetic alopecia in adolescents: A report of 43 cases
*Topical Antiandrogens*
7:19 CB-03-01 (Clascoterone)
8:22 KX-826 (Pyrilutamide)
9:06 RU58841
10:41 My Thoughts
1. **Studies directly addressing Androgenetic Alopecia**:
- RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia and Hirsutism*
www.sciencedirect.com/science...
- Percutaneous absorption of a new [RU 58841] antiandrogen included in liposomes or in solution
www.sciencedirect.com/science...
- The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: A Outpatient-Based Study
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/23717...
sci-hub.ee/10.5021/ad.2013.25...
- Androgenetic alopecia in adolescents: A report of 43 cases
pubmed.ncbi.nlm.nih.gov/17040...
onlinelibrary.wiley.com/doi/e...
- To Evaluate Efficacy, Safety, and Tolerability of KX-826 in Male Subjects With Androgenetic Alopecia
classic.clinicaltrials.gov/ct...
- Kintor succeeds in Phase II study of US males with androgenetic alopecia
www.clinicaltrialsarena.com/n...
- COSMO ANNOUNCES THE BEGINNING OF THE PHASE III TRIALS IN MALES FOR THE TREATMENT OF ANDROGENETIC ALOPECIA
www.cosmopharma.com/news-and-...
2. **Studies addressing treatments with potential relevance to Androgenetic Alopecia**:
- Pyrilutamide (KX-826): a potential FIC AR antagonist for topical dermatological use
pdf.dfcfw.com/pdf/H3_AP2020072...
3. **Studies related to Acne**:
- Efficacy and Safety of Topical Clascoterone Cream, 1%, for Treatment in Patients With Facial Acne: Two Phase 3 Randomized Clinical Trials
www.researchgate.net/publicat...
- Open-label, long-term extension study to evaluate the safety of clascoterone (CB-03-01) cream, 1% twice daily, in patients with acne vulgaris
www.jaad.org/article/S0190-96...
4. **General or Foundational References**:
- Clascoterone
go.drugbank.com/drugs/DB12499)
- Biochemistry, Dihydrotestosterone
www.ncbi.nlm.nih.gov/books/NB...
Негізгі бет DHT Itch: The Connection Between Acne and Male Pattern Baldness
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