DNA replication termination in prokaryotes - This DNA replication process lecture will explain the role of Tus and Ter complex in the prokaryotic DNA replication termination. I take E. coli bacteria as an example and I explained the DNA replication termination in E. coli in step-by-step details although the mechanism can be applied to different prokaryotes.
DNA replication will be the procedure for producing 2 equivalent reproductions collected from one of first DNA molecule. This kind of natural method takes place in all residing organisms which is the basis intended for natural monetary gift. DNA comprises of 2 strands in addition to each and every follicle from the first DNA molecule acts being a web template to the manufacturing from the secondary follicle, an operation called semiconservative replication. Cell phone proofreading in addition to error-checking things ensure around great fidelity intended for DNA replication.
Firing involving DNA reproduction within E. coli can be accomplished by using termination sequences and also the Tus healthy proteins. These kind of sequences encourage the a couple reproduction forks to feed in only a single route, however, not the opposite.
DNA reproduction to begin with makes a couple catenated or joined round DNA duplexes, each and every containing a single parental strand then one newly synthesised strand (by mother nature involving semiconservative replication). This specific catenation can be visualised seeing that a couple interlinked happens to be which in turn are not lost. Topoisomerase IV within E. coli unlinks or decatenates the two round DNA duplexes.
DNA replication by Suman Bhattacharya
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