#functionalmedicine #dopamine
Dr. Jawad discusses low dopamine issues.
Do You suffer from low dopamine?
What Is Dopamine?
Dopamine is a neurotransmitter that functions in the brain and the body. Dopamine is needed to produce the other catecholamines: Norepinephrine and Epinephrine. A deficiency in Dopamine will lead to depression, lack of motivation, lack of pleasure. While dopamine is often referred to as the “pleasure chemical,” this is a misnomer, as dopamine doesn’t actually produce pleasure. It does, however, reinforce feelings of pleasure by connecting sensations of pleasure to certain behaviors.
Dopamine is a neurotransmitter made in the brain. Basically, it acts as a chemical messenger between neurons.
Dopamine is released when your brain is expecting a reward.
When you come to associate a certain activity with pleasure, mere anticipation may be enough to raise dopamine levels. It could be a certain food, sex, shopping, or just about anything else that you enjoy.
There are several areas of the brain where dopamine neurons are concentrated. The largest are the substantia nigra and ventral tegmental area in the midbrain. Other areas include the hypothalamus, olfactory bulb, and retina.
There are several major dopamine pathways that carry dopamine from these areas of concentration to other parts of the brain. Some of the largest are the mesostriatal or nigrostriatal pathway, which stretches from the substantia nigra to the striatum, the mesolimbic pathway, which stretches from the ventral tegmental area to the nucleus accumbens and other limbic structures, and the mesocortical pathway, which stretches from the ventral tegmental area throughout the cerebral cortex.
Dopamine acts at G-protein coupled receptors and there are at least 5 subtypes of the dopamine receptor. Dopamine is removed from the synaptic cleft by a transporter protein called the dopamine transporter.
Like any neurotransmitter, the functions of dopamine are complex, and can’t be fully explained with just a short summary. Dopamine is linked to movement due to disorders like Parkinson’s disease that involve dopamine deficiencies. It is also often associated with the processing of rewarding experiences. However, dopamine also plays a role in many other functions.
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DR. JINAAN JAWAD
D.C., DACNB, FACFN, FIAMA, CFMP
Dr. Jawad is a Board Certified Chiropractic Neurologist and Acupuncturist. In addition, a Diplomat for the American Chiropractic Neurology Board, Fellow of the American College of Functional Neurology as well as Fellow of the International Academy of Medical Acupuncture. He is a Certified Functional Medicine Practitioner.
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