#GFN23 Keynote 2: The role of nicotinic systems in brain disorders - Full Session | ENGLISH
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Keynote: Paul Newhouse
Host: Sud Patwardhan
Respondent: Konstantinos Farsalinos
While generally thought of as a substance of abuse, nicotine when separated from smoking and inhalation appears to have the potential for therapeutic properties for a range of cognitive and age-related disorders without significant abuse liability. Nicotine binds to multiple subtypes of nicotinic cholinergic receptors in the brain that modulate a variety of neuronal functions. Recent advances have expanded our understanding of how stimulation or blockade of nicotinic receptors affects brain activity, cortical networks, and behavior. This presentation will cover new advances in understanding the role of nicotinic receptor systems on brain function and explore the potential for therapeutic use of nicotine as a treatment or adjunct in the therapy of disorders such as late life depression, mild cognitive impairment, and related disorders of cognitive aging.
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