Cell & Gene Therapy Insights' FastFacts video
Published: December 20, 2021
Watch the video to learn about:
- Importance of sample pretreatment before first chromatographic step
- Rapid downstream process of AAV with emphasis on chromatographic step of CIMmultus SO3 capture
- Three different ligands full enrichment of AAV
- Why orthogonal analytics is the key in downstream development and what are the options
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CHAPTERS:
0:00 Introduction
0:43 Cornerstone Biomanufacturing Development Services
1:52 Rapid chromatography processes by convective mass transport
3:03 Simple downstream processing of a complex AAV sample
5:14 TFF in combination with salt-tolerant nuclease treatment
6:20 CIMmultus SO3 capture is the heart of purification
7:07 CIMmultus SO3 capture and why CIP is so important?
8:29 Polishing step: Full enrichment made easy
9:34 To enable fast process development high performance analytics is mandatory
10:51 Multi-detector UC profiling
Негізгі бет Fast chromatography of AAV - purification and analytics
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