The interesting thing is that this guy is good at everything , he is an asset for science
@bobhiggins8591
7 жыл бұрын
Why am I paying a university thousands of dollars when this guy offers the same thing but vastly superior for free?
@faisalal-sammarraie9140
7 жыл бұрын
bob higgins you won't get a degree by watching his videos
@TheDuvee6
6 жыл бұрын
papers...
@giorgosgranitsiotis
5 жыл бұрын
For a paper actually...
@arshdeepkaur4092
2 жыл бұрын
Here we get knowledge, there a piece of paper.
@minagamal7566
5 жыл бұрын
This guy is worth donation we should all at least support by any amount of money we can afford
@veronikamuller967
6 ай бұрын
Honestly you couldn’t have explained better. You saved biochemistry in my medicine studies, THANK YOU!
@ishaannandwani2537
2 жыл бұрын
7 years later and i'm commenting because your videos have been so incredibly helpful for the mcat. thank you so much for these.
@alyssa-abcde
4 жыл бұрын
Forever grateful to you, sir. Thank you for being a GREAT teacher!
@aanalbhatt2444
8 жыл бұрын
things made so simpler! wayy to go #AKLectures :) thank you!!
@AKLECTURES
8 жыл бұрын
+Aanal Bhatt you're welcome! :-) glad to hear that
@naderrefai7083
7 жыл бұрын
Saving medical students once again AK Lectures. Keep it up!!!
@nikkyuong6793
5 жыл бұрын
I freaked out earlier today since I could not catch up with the materials... And I found your series.... THANK YOU! THANK YOU SO MUCH!!!
@fatimayasin3971
3 жыл бұрын
I’m so so thankful for you You are perfect @Ak LECTURES
@immanuelrod1
6 жыл бұрын
Basically, you're lectures will most likely help me become a doctor. When that happens and if you're still around, I'm making a fat donation! You are literally a dream maker!
@healthinsuranceguru4633
4 жыл бұрын
i wish he would put his older lectures in a playlist too bc this material is way over my head.
@Eric-sq4hd
4 жыл бұрын
this dominates my textbook. didn't understand anything after 30 minutes reading learned it here in 13:25
@Haani36
3 жыл бұрын
Sir!. You are doing a great Job... Your way to teach is outstanding...! I can't imagine my Biochemistry without you.. Stay Blessed ❤️❤️❤️
@soargamer1437
4 жыл бұрын
Oy my God this guy teaches way better than any lecturer l have. He is a superstar and worth donating to. Keep it up once l am done with my school l must will for sure donate
@anusha4975
Жыл бұрын
I just took my biochem final and I could literally see your diagrams in my head when I answered questions. Thank you :)
@stefanastefanova5
6 ай бұрын
Incredibly helpful! Thank you, Andrey K!✊🙏
@omerabbas745
9 жыл бұрын
your great! would be really good if you get a little into the clinical aspect of things, but I genuinely appreciate it
@ahmadbilal7724
3 жыл бұрын
Thanks a lot....In few minutes you explain what our Professors explain in hours.
@anastasiavasilopoulou4450
4 жыл бұрын
YOU ARE THE BEST!!I got a 9/10 because of you!!!!
@tabakhan2330
2 жыл бұрын
He gives lecture a way better than our universities professors
@OzOz17
3 ай бұрын
best professor ever
@diptibarvadia8797
7 жыл бұрын
this is so helpful i wish u had a video on photosynthesis
@blackeywhiteyakilaforlife182
7 жыл бұрын
You have made it very much easier to understand!! Detailed and awesome explanation:) Thanks aLot!!
@sarahhe.5455
5 жыл бұрын
I love your videos!!! It is the most clear explanation of biochem I have ever seen. I have been staring at the book for hours, and went to my prof's office many times and got nothing. I feel it's such a waste of money and time to go a university while better teachers are out there teach for free or with much lower cost. Stupid outdated and rigid education system
@victorchimaobi9787
6 жыл бұрын
i dnt complain when i miss some classes because i knw where to get d best explanations.... thanks alot
@simchami
7 жыл бұрын
you are the best ever ....thnk you sooooooooooo much ..you always make it so clear and simple for me .....love youuuuuuuuu
@mayazazu7070
8 жыл бұрын
These lectures are fantastic, thank you so much! :)
@denrightSN
4 жыл бұрын
these lectures are extremely helpful. thank you.
@benjamintrammell8541
4 жыл бұрын
Any other medical students here? This guy has literally saved me. I hate biochemistry but he makes it slightly more tolerable.
@aminebi4324
8 жыл бұрын
Thanks for your useful presentations !
@219malcolm
7 жыл бұрын
Great job with this video!!! Very informative!! Very simple!!!
@mohammadriaz777
8 жыл бұрын
thanks for the video its made the process easier for me Great work! Good luck!
@TheTootah2009
8 жыл бұрын
the best explanation 👌thank you 💚
@yogeeta-4477
3 жыл бұрын
You are best✨ You know how to simplify biochemistry Thanks alot 🤗🤩
@ashokmehta6185
5 жыл бұрын
Wonderfully explained the most difficult and boring subject "BIOCHEMISTRY" in Highly digestible form. Thank you SIR
@ridsbutterfly9850
7 жыл бұрын
Awesome lecture. Thank you sir..
@mubasharali4386
7 жыл бұрын
Rids Butterfly 😍
@alejandrojjimenezquintero2957
6 жыл бұрын
8:58 doesnt hexokinase form glucose-6-phoshate? why does it form directly the glucose-1-P?
@Cass_i
4 жыл бұрын
Because of the fact that it was just cleaved from the 6th carbon on the linear chain leaving the first carbon open and reactive
@jenniferlawrencefan8
3 жыл бұрын
hexokinase (so far what ive learned) only plays a part in a specific step in glycolysis. Hexokinase doesnt really form G6P, its just an enzyme that does a job in a particular way, meaning u shouldnt see it as hexokinase forms G6P, its more liek what hexokinase does to glucose forms G6P. There are multiple pathways to creating G6P and degradation of glycogen bypasses the need for hexokinase because another mecanism is used instead- as explained in this video. During glycolysis, hexokinase takes glucose and phosphorylates it into G6P by adding a phosphate group at the 6th carbon on glucose. This reaction seen in this video, however, doesnt start with glucose, it starts with glycogen. So theres no need for hexokinase because theres already a phosphate group on the glucose 1 phosphate sugar, only it is on carbon 1 and not carbon 6, which is why the whole 3rd step in the video transforms G1P into G6P. Basically, this process is different because glucose is a 6-carbon sugar without phosphate group, whereas in this situation *glycogen phosphorylate* will be adding a phosphate group to the glucose that was cleaved from the alpha 1-4 glycosidic bond, creating G1P. Hexokinase cant rlly work with G1P (in this context), only with glucose. hope this helps whoevers having the same question :)
@nourhanmoustafa7099
7 жыл бұрын
you made biochemistry an easy interesting science☺ big thank you ..wish you all the best #AkLectures
@ebarolajinefer
6 жыл бұрын
Thank you!! Everything are so clear!
@omamashahid3250
9 жыл бұрын
I really appreciate your effort (y)
@halaissa853
7 жыл бұрын
Thank you very much, that was so helpful :)
@MrTurbojet93
6 жыл бұрын
Excellent job this helped so much!
@esthersim1974
4 жыл бұрын
You were sent from heaven, I am sure of it.
@R134able
7 жыл бұрын
thank you so much!!! u explained it way better than my lectuers :D
@nuevopurpleplanttissuecult7128
7 жыл бұрын
great video!! Thank you very much for the clear n very digestible information!👌✌
@ReglaRojas
4 жыл бұрын
this was extremely helpful, thank you so much
@lardigmer
5 жыл бұрын
Thank you a lot! I think there should be an H2O in the reaction that is catalyzed by alpha-1,6-glucosidase, when a glucose molecule is released. :) The remaining glycogen + H2O ---(alpha-1,6-glucosidase)--> glucose + The remaining glycogen
@juliobracamonte9777
5 жыл бұрын
Thanks
@AymanSmairat
7 жыл бұрын
I swear that you are better than my lecturer 😌
@jawadjaradat9426
7 жыл бұрын
وحش ايمن :)
@anne8nOtrn
7 жыл бұрын
thank you so much i was desperate with biochemistry :P big thanks you are the best !
@krisharivera4935
3 жыл бұрын
Im not sure if my university teaches glycogen breakdown or my mental breakdown
@amounanina8642
7 жыл бұрын
So blessed . tysm for these lectures
@roaahany2779
Жыл бұрын
Really ur videos care magnificent thx a bunch
@mujahidjalal6556
2 жыл бұрын
Thank u so much dear sir...!
@cecejamesable
6 жыл бұрын
God bless you, sir. God bless you!
@gabrielsanzvillegas1707
8 жыл бұрын
This is amazing. Thank you!
@kerolloseskander4035
4 жыл бұрын
Great job thank you
@TheNatttyJ
4 жыл бұрын
Brilliant!
@1800gingers
4 жыл бұрын
really helped thank you
@francescabaysa1773
Жыл бұрын
AMAZING THANK YOU
@mahamraouf5546
6 жыл бұрын
thank u sooooooo muchhh sir excellent video i have ever watched
@agent475816
6 жыл бұрын
Why does hexokinase form glucose-1-phosphate just so phophoglucomutase can convert it to glucose-6-phosphate from the α(1-->6) cleaved glucose by α(1-->6) glucosidase? Wouldn't it be more efficient if hexokinase just forms the glucose-6-phosphate just like it does in glycolysis?
@victorwainaina2584
6 жыл бұрын
I was wondering the same thing. Hopefully some magical person comes and explains. If you have an idea why since you made this comment 3months ago, I'd appreciate the answer...though when I come to think of it I'll probably not need the info once today's exam is done, hahaha.
@wajihaaldabbas5418
6 жыл бұрын
enzymes and substrate have absolute specificity...one enzyme can not catalayse another substrate
@user-hw9bh9ro3t
5 жыл бұрын
they have different function dear ….. hexokinase is convert glucose to glucose -6-phosphate by using ATP but the function of phosphoglucomutase just transfer p group fromone side to another in the same molecule و الله أعلم
@jelenatubic6488
5 жыл бұрын
Thank you sooooo much, this is very helpful to me,.....Awesome lecture :DDDD
@sarahha.4267
7 жыл бұрын
incredibly amazing:') big thanks
@OzOz17
3 ай бұрын
Andrey K for president !!!!!
@jenniferlawrencefan8
3 жыл бұрын
I LOVE YOU. i mean it with all my heart.
@nathansteadman2831
6 жыл бұрын
Would the free glucose that was released from it's alpha 1,6- glycobond not just be exported straight out of the liver? Or is this model representative of muscle cells? Thanks for the videos. Very concise and efficient
@veronicamoubarek9933
8 жыл бұрын
Awesome videos!
@dibagabbary2066
4 жыл бұрын
thank you so much
@giorgosgranitsiotis
4 жыл бұрын
Thank you sir
@zainabali2062
5 жыл бұрын
You are great one😊😊💜
@tommyle5952
6 жыл бұрын
So in both the glycogenesis and glycogenolysis videos, you said that the phosphoryl group is essentially moved from carbon 1 to carbon 6. Is it because the phosphoryl group always starts at carbon 1 relative to the oxygen?
@whiplashdamn5978
3 жыл бұрын
awesome just awesome
@ayeshaumer1315
2 жыл бұрын
what primay first product formed by glycogen decomposition????
@rakeshparida8829
6 жыл бұрын
u r the best sir
@AmyStylinson
6 жыл бұрын
Why does hexokinase form glucose-6-phosphate in glycolysis but it forms glucose-1-phosphate in this situation?
@musa4060
5 жыл бұрын
Thank you!
@hyderali692
5 жыл бұрын
Can you make a video on "Breakdown of starch" ? Please @AK lectures
@ritupriyadebnath
6 жыл бұрын
Thank you so much 💓
@korenpollak8344
5 жыл бұрын
Thank you !!
@ehsanhumayun689
8 жыл бұрын
Hi your way of teaching is excellent but in this lecture i have 2 questions 1st is that is the degradation of glycogen is started only at the alpha 1-6 chain or it is also occured at alpha 1-4 chain at same time? 2nd glucose is converted to glucose 6 phosphate by any cell to capture it inside cell and to prevent from escaping. in third step glucose 6 phosphate is synthesised now can u explain me that how it is transported to other cells from liver. How could it escaped out from liver cell when in form of glucose 6 phosphate
@alialhilo2289
8 жыл бұрын
Thank you!!!!! Just a simple Q: Step 3 is it reversible?
@metaworldpeacetoday
3 жыл бұрын
Fabulous lectures thank u, btw... are u Ukranian?
@AKLECTURES
3 жыл бұрын
Nope.
@saadrashidusmani832
5 жыл бұрын
bravo from Pakistan
@frankienoel9937
7 жыл бұрын
what is the name of the enzyme in eukaryotes that replaces transferase and alpha 1-6 glucosidase? is it hexokinase? +Ak Lectures
@ehsanhumayun689
8 жыл бұрын
And also glycogen is broken down to provide glucose so if we produce glucose 6 phosphate in third step how it converted in to glucose as we mention conversion of glucose to glucose 6 phosphate as irreversible reaction
@saunyboy123
8 жыл бұрын
+Ehsan Humayun Glucose to G6P is a reversible reaction catalysed by Hexokinase
@protosist
7 жыл бұрын
Ehsan Humayun There is a glucose-6-phosphatase in the liver that cleaves the phosphate off if there is any need to rise the blood sugar level.
@ehsanhumayun689
7 жыл бұрын
Andrei Munteanu if glucose 6 P is in muscle cells how could glucose 6 phosphatase of liver will reverse it as glucose 6 P form is only present inside cells so they can't escape out
@protosist
7 жыл бұрын
Ehsan Humayun Yes, there is no g-6-phosphatase in the muscle cell, and in fact muscle cells don't have the ability to rise the blood sugar level unless g-6-p undergoes anerobic glycolysis, gets transformed into lactate that travels to the liver or the kidneys where it becomes glucose by GNG.
@lanana939
5 жыл бұрын
Great video!! thank you! :)
@dustinsatti2086
6 жыл бұрын
dude you are awesome
@user-cj4bf4gz7n
5 жыл бұрын
At the first I will thank you so much for this encrideble explanation and for your time which u spend to explain these lectures❤❤❤ but I have a question is the transferase and alpha1,4-glucosidase the same thing with the debranching enzyme??? #aklectures
@inezchong3000
4 жыл бұрын
it's alpha-1,6-glucosidase; and yes, they're both debranching enzymes! :D
@tun6006
7 жыл бұрын
Is the remaining residual core not broken down further?
@Sara-wt4hh
5 жыл бұрын
Thanks 💙💙💙💙💙💙
@nanaminoz8159
6 жыл бұрын
Awesome *-*
@rakeshparida8829
6 жыл бұрын
can y give some notes in your video in pdf from
@ritupriyadebnath
6 жыл бұрын
Love it
@arshisheik9980
6 жыл бұрын
Thanku sir ☺☺☺
@ritwikmandal1928
6 жыл бұрын
do u follow stryer for this references?
@jose7777777777777777
7 жыл бұрын
at about 4:28 you said Glucose and I think you meant glycogen
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