In this video, Patrick Kelly guides you through the microbiology of anthrax disease before telling the story of Robert Koch, whose research on anthrax helped establish the germ theory of disease, a cornerstone of microbiology. Learn how early discoveries paved the way for modern antibiotics and revolutionized our approach to infectious diseases. Whether you're a microbiology enthusiast or just curious about medical history, this video offers a comprehensive overview of anthrax from its origins to contemporary treatment methods.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
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📜 S O U R C E S 📜
An annotated version of the script can be found here: / 104362006
CDC History of Anthrax www.cdc.gov/anthrax/basics/an...
Human Anthrax: Update of the Diagnosis and Treatment (2023)
www.mdpi.com/2075-4418/13/6/1056
Biostats Anthrax articles www.ncbi.nlm.nih.gov/books/NB...
Baylor Anthrax article www.bcm.edu/departments/molec...
CDC Anthrax routes www.cdc.gov/anthrax/basics/ty...
Ins and Outs of Anthrax Toxin (2016) www.ncbi.nlm.nih.gov/pmc/arti...
Anthrax: A Disease and a Weapon (2005) citeseerx.ist.psu.edu/documen...
Fournier 1769 book www.google.com/books/edition/...
Koch’s Original 1876 paper archive.org/details/beitrgezu...
Koch’s 1877 paper with first anthrax images
archive.org/details/beitrgezu...
Pouilly le Fort Experiment (FR 1881 / ENG 2002) www.ncbi.nlm.nih.gov/pmc/arti...
Robert Koch and the ‘golden age’ of bacteriology (2009) www.ijidonline.com/article/S1...
The first live attenuated vaccines (2020) www.nature.com/articles/d4285...
Anthrax vaccines at the PI (2024) www.mdpi.com/2072-6651/16/2/66
Anthrax and the wool trade (1902) www.researchgate.net/publicat...
John Henry Bell (2002) www.ncbi.nlm.nih.gov/pmc/arti...
Brachman Vaccine Paper (1962) www.ncbi.nlm.nih.gov/pmc/arti...
Combinations of Monoclonal Antibodies to Anthrax Toxin (2013) www.ncbi.nlm.nih.gov/pmc/arti...
Raxibacumab approval from FDA www.accessdata.fda.gov/drugsa...
Obiltoxaximab (2016) pubmed.ncbi.nlm.nih.gov/27085...
Anthim (obiltoxiaximab) anthim.com/what-is-anthim.html
Antibodies against Anthrax Toxins (2022) www.mdpi.com/2072-6651/14/3/172
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⌛T I M E S T A M P S ⌛
0:00 intro
0:57 Microbiology of Anthrax Disease
4:27 Early History of Anthrax
6:28 Nicolas Fournier
8:15 Davaine and Rayer find bacillus anthracis
10:10 Robert Koch's work on anthrax
18:37 Modern treatments for anthrax
14:56 Louis Pasteur, Pouilley-le-Fort, and the anthrax vaccine
#historyofmedicine #medicalhistory
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