I watched 3 to 4 other videos to understand DNA fingerprinting but none of them cleared the topic as u did thanksssss
@LearningCurveScience
3 жыл бұрын
Thank you very much for saying that. I'm glad you found my explanation useful. Even though the radioactive DNA method isn't really used anymore, it is still used in teaching.
@rehmanrupiya7587
Жыл бұрын
I have tried multiple times to understand from our NCERT textbook but everytime i failed. Thank you so much for explaining in a very simple way.
@Eterrath
2 жыл бұрын
This is an amazing video. I've seen multiple videos on DNA fingerprinting and this is the only one that manages to answer all my curious high school level questions without being too technical to fry my brain. Glad you're still uploading videos. Hugely underrated. Subscribed.
@LearningCurveScience
2 жыл бұрын
Thank you very much. I am actually an educator in the UK, and so I try to make my videos understandable by as many people as possible. I'm glad you enjoyed it, and thank you very much for subscribing
@learner3268
2 жыл бұрын
Same here
@robertm7120
Жыл бұрын
Finally !! An explanation of how a DNA sample can be transformed into a DNA profile ! Thank you so much.
@andydrews4439
2 жыл бұрын
I did a gel electrophoresis lab in my cell biology lab. Took us three weeks to complete. Very cool.
@shmkrar1153
Жыл бұрын
This video is awesome! I had great trouble understanding DNA fingerprinting. Now, I've got it and find it really fascinating
@tinopetersson2577
2 жыл бұрын
Why does this channel not have more subscribers? Thank you for a great piece of content!
@LearningCurveScience
2 жыл бұрын
Thank you very much for the lovely comments.
@WitchyLady21
5 ай бұрын
Loved the Doctor Who reference! Great video! Thank you for doing this. It helped me pass my class. :)
@kinjalchandpara8603
3 жыл бұрын
Excellent !!!!!!!🙌🏻 None can forget this topic after watching this video. Very well explained 👌🏻
@LearningCurveScience
3 жыл бұрын
Thank you very much for such a lovely comment. I'm glad you enjoyed it.
@mamtalall6750
Жыл бұрын
Sir, your explanation is simple and so easy to understand. Especially for students in a resource poor set up. Thank you so much.
@Mikeymouse1
Жыл бұрын
Thank you so much. I normally need very detailed explanation with visual and this is perfect. 😊
@wonderman8537
2 жыл бұрын
Oh my goodness me. I can't believe this is a 2k sub channel and such professional video
@islamicbro
2 жыл бұрын
I saw tooo many videos of dna fingerprinting. But this one is what I was looking for❤️
@LearningCurveScience
2 жыл бұрын
Thank you very much for your lovely comment
@ReflectiveLayerFilm
4 жыл бұрын
Great video/explanation. Now I know why it's expensive to do DNA fingerprinting.
@LearningCurveScience
4 жыл бұрын
Thank you, I thought I'd go back to my biological roots for a video. Biology is my comfort zone I suppose. For quite a few years, there was only 1 lab in the world doing DNA fingerprints.
@chiumanhin618
3 жыл бұрын
I have been looking for video like this so long!!thankyouuuuuu!
@LearningCurveScience
3 жыл бұрын
Good, I'm glad you found what you were looking for. Thank you for watching.
@noorashaju7892
2 жыл бұрын
And finally here it is.. This still helps a lot for me. Thank you so much sir for your wonderful explanation.
@eduardoborges1202
3 жыл бұрын
Man, you did a great job here. Thanks.
@LearningCurveScience
3 жыл бұрын
Thank you very much. I'm glad that you enjoyed the video.
@HEARDIFFERENT
4 жыл бұрын
Excellent video once again. ❤️❤️❤️👏👏👏🔥🔥🔥
@LearningCurveScience
4 жыл бұрын
Thanks very much. I'm so glad you enjoy my videos. Thank you.
@ShortsOG123
2 жыл бұрын
Thanku so much it is the bestt explanation on DNA fingerprinting💕
@gulshanmaurya5512
2 жыл бұрын
Great explain ❤️ love from India 🇮🇳
@savanrathod6021
2 жыл бұрын
Very simply explained,thank you sir
@lilyc302
9 ай бұрын
great explanation, other youtube videos were too vague
@nazlkarac5367
Жыл бұрын
thank you for this amazing video from Türkiye
@mimansamishra5833
3 жыл бұрын
Your videos are really helpful!
@LearningCurveScience
3 жыл бұрын
Thank you very much. I'm glad you enjoy them.
@diegocorales9284
2 жыл бұрын
2:02 is epic!
@LearningCurveScience
2 жыл бұрын
Thank you I'm glad you enjoyed the video
@janebarnes4386
Жыл бұрын
Back to class. I’ll get a c- w all science classes. -an MA + writer
@virenderbhardwaj3137
Жыл бұрын
4:20 how do we make these probes? ...i.e how do we know they're gonna be complementary to the sample dna pieces??
@wicked.peaches.1797
Жыл бұрын
Loved the explanation and Doctor Who reference. 😂
@akshitaaaaatiwari2568
3 жыл бұрын
Awsomeeeeeeee
@LearningCurveScience
3 жыл бұрын
Thank you very much, that's very kind
@MezGaming-zp5ei
5 ай бұрын
Now i understood Thanks!
@ghoulwizard1901
3 жыл бұрын
I don’t really get the part where the pieces of complementary DNA are made radioactive. Can you elaborate on that? So the pieces of DNA added are complementary to the DNA strand we used as sample?
@LearningCurveScience
3 жыл бұрын
Yes I use pieces of DNA that I know to be complementary to the sequences in the sample. These pieces of DNA are made artificially and are made to be radioactive. We do the same thing today with pieces of DNA that have dye molecules attached to them. It just helps us to see where our DNA samples ended up. I hope that helps.
@ghoulwizard1901
3 жыл бұрын
@@LearningCurveScience Oh, thank you so much! I understand now!
@ashishrokade3488
Жыл бұрын
Thank you so much
@daytodayupdate5922
3 жыл бұрын
Very well explained. Do we use EtBr in gel electrophoresis step of fingerprinting? If not then what is the reason of it?
@LearningCurveScience
3 жыл бұрын
Ethidium Bromide is a dye that fluoresces in the presence of DNA. It is usually used to make the band more easy to see. It means you don't have to bother with the radioactive DNA probes.
@utkarshswaroop_0306
7 күн бұрын
Thank you❤❤
@vachan-maker
Жыл бұрын
excellent
@pankajakshigk7842
2 жыл бұрын
Thank you very much It was very helpfull
@laladnikuku3ka
3 жыл бұрын
thank you for the video
@LearningCurveScience
3 жыл бұрын
You're welcome. I'm glad you enjoyed it.
@globaltutorialscenterkawar4176
9 ай бұрын
Thanks sir
@steamerSama
2 жыл бұрын
gr8 video mate
@LearningCurveScience
2 жыл бұрын
Thank you very much, I'm glad you enjoyed it.
@kiranyadav7387
3 жыл бұрын
is there any relation between the restriction enzymes used in RFLP and location of STRs?
@LearningCurveScience
3 жыл бұрын
Interesting question. I'm not entirely sure. You need to make sure that a cut is made before the STR and then again after the STR. As long as the cuts are made in the same place in everyone's DNA, then it is just the length of the STR that differs.
@unknown5904
2 жыл бұрын
Why don't we stop after electrophoresis, isn't there a dye that is added to the fragments during electrophoresis. I mean when is it necessary to continue to jeffreys technique?
@LearningCurveScience
2 жыл бұрын
That's a good question, and the answer I don't really know, but I have some ideas. Firstly this is the technique that is often used in education. Also having seen a number of these gels, they lose water and shrivel with time. This would alter the gel and potentially make them unusable. Also I'm not sure how stable. There are solutions that do use dye (I've used some myself). Sadly when they dry out they become unusable. Hope that helps.
@unknown5904
2 жыл бұрын
@@LearningCurveScience oh thanks so much
@vivekgautam6943
3 жыл бұрын
U r wonderful buddy.
@LearningCurveScience
3 жыл бұрын
Thank you, I'm glad you enjoyed the video
@noureenadil1612
Жыл бұрын
Wonderful 👍
@tamarafakih1080
2 жыл бұрын
thank you so much this was very beneficial but i wanted to ask on which basis is the radioactive probe chosen, or to be clearer, what is the specific DNA sequence that i want it to be hybridized by this probe and why?
@Okamy1993
2 жыл бұрын
You dont need to tag the bases, for example it can pair with the Phosphate or sugar Rests every DNA has.
@manar-nasser
2 жыл бұрын
Your voice make me feel like I'm watching a movie
@WanderingKnights
4 жыл бұрын
You are great at explaining
@LearningCurveScience
4 жыл бұрын
Thank you, I'm glad you think so. DNA is such a fascinating molecule.
@ayushpandeymbbs1776
2 жыл бұрын
Sir after gelectrophoresis if both semple has diffrent arrangement of DNA fragments then here why we can not decide both DNA semple are of different persons????.... Why we go further and perform autoradiography and all ???????
@ayushpandeymbbs1776
2 жыл бұрын
We can see DNA arrangement in gel electrophoresis strp by stanning with ethidium bromide and UV rays ...????
@LearningCurveScience
2 жыл бұрын
The method I discussed is just one way of making the fragments visible. We need to make them visible to see if there are any differences. This is just one way, and it's the way that's usually taught in schools (in the UK at least). I hope that makes sense
@ayushpandeymbbs1776
2 жыл бұрын
@@LearningCurveScience ok sir love from India ❤️
@girishshankarrai6488
3 жыл бұрын
Sir the repeative sequence which are found in the fragments why they are only present in narrow band which are rich in A T content 🤷🏻♀️
@LearningCurveScience
3 жыл бұрын
That's a really interesting question, thank you. I'm not sure why the sequences are found in narrow bands, but since they are non-coding they would not be affected by mutations that add extra copies of the sequences (these can happen at any time). Also quite a few of them are rich in A and T, but not all of them. The STR called FGA has the sequence CTTT, but it does appear that a lot of them have A and T. I'm not sure why, but excellent question.
@moutaihaitam2959
8 ай бұрын
is the same analysis we do to identify the parents ?
@LearningCurveScience
8 ай бұрын
Yes it is, it works on the same principle.
@ThePhotogalleria
3 жыл бұрын
The radioactive method has not been used since 1995 or so. So this video outdated some 25 years ago.
@LearningCurveScience
3 жыл бұрын
Ooh interesting, I didn't know that, thank you. I'm a teacher rather than a research biologist and the radioactive probe technique is still taught. I know we don't use the RFLP analysis anymore but I thought it was interesting so I included it in the video. Whenever I've done a gel electrophoresis I've always used dyed probes, but I always assumed they were just used for education. Interesting to learn something new, thank you.
@PrakashChandraJoshii
2 жыл бұрын
Fucking deep hard next level explaining man 🏆🔥🙏
@LearningCurveScience
2 жыл бұрын
Thank you very much, I'm glad you enjoyed it
@nishantraj440
3 жыл бұрын
wow ❤
@LearningCurveScience
3 жыл бұрын
DNA is awesome, I find it fascinating. Thank you for watching the video.
@AnnaRossa6088
2 жыл бұрын
Doctor who reference!
@LearningCurveScience
2 жыл бұрын
I am a massive Doctor Who fan and geek. My time travel is full of Doctor Who references (and I do mean full)
@rahulkumar10tha57
2 жыл бұрын
Woah mannnn
@bisolailias3820
2 жыл бұрын
KZitem refused my like
@safazuhair2420
Жыл бұрын
thank you so mush 😭 thank you thank you soooo much , allah bless you ❤
@Itachi-1503
10 ай бұрын
3D visualisation is the best way of teaching so that all can get it very easily... Your explanation is amazing... Keep it up🎉🎉
@normannokes9513
Жыл бұрын
The world has received a wonderful gift. Undeniable evidence will upset many corruptible personalities. Thank you Sir Alec.
@TheTransporter007
Жыл бұрын
You sound.... Familiar. 🤔
@learner3268
2 жыл бұрын
First time ever being able to understand DNA profiling in a much better way after watching a number of videos finally
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