GLP-1 agonist medications have been a popular topic of discussion recently. While this weight loss drug was designed for obesity, GLP-1 agonists like Ozempic have made their way into Hollywood. This has people questioning their safety and possible health risks, especially in the long run. Are GLP-1 agonists a quick fix for weight loss or a lifetime prescription? Who should be prescribed this medication, and what are the possible side effects?
This Longevity by Design episode features an interview with Dr. Spencer Nadolsky-An obesity and lipid specialist physician. Dr. Nadolsky explains how GLP-1 medications cause weight loss, answers questions about safety concerns, and discusses interesting patient stories about how people react to this medication. Dr. Nadolsky has extensive patient experience with GLP-1 agonist drugs and is very knowledgeable about their current use and future potential.
Why Dr. Nadolsky became a physician: (2:00-4:13)
What is cardiometabolic medicine?: (4:13-5:17)
What is a “healthy” metabolism?: (5:17-7:37)
How does diet impact glucose regulation: (7:37-10:20)
Why has insulin resistance increased in the past decade?: (10:20-11:45)
Ethnicity impacts BMI cutoffs: (11:45-12:57)
Is obesity a choice?: (12:57-17:40)
How socioeconomic status impacts obesity: (17:40-21:30)
What's better: A BMI score or a DEXA scan?: (21:30-25:33)
How strength training improves healthspan: (25:33-32:32)
What a fasting insulin blood test tells you: (32:32-36:58)
Health risks of insulin resistance: (35:15-38:08)
How insulin resistance can increase ApoB: (38:08-39:25)
How does ApoB predict heart disease risk?: (39:25-42:50)
Why isn't ApoB included in typical lipid panels?: (42:50-44:25)
Behavioral science and clinical practice: (44:25-50:06)
How do GLP-1 agonists cause weight loss? (50:06-56:03)
Negative side effects of GLP-1 medications: (56:03-57:36)
Price of GLP-1s: (57:36-58:53)
GLP-1: A short term quick fix or a lifetime prescription?: (58:53-1:02:19)
Biggest health myths on social media: (1:02:19-1:08:45)
Top tip for healthspan: (1:08:45-end)
Longevity by Design is produced by InsideTracker, your data-driven wellness guide for optimizing your healthspan. For a limited time, visit hubs.li/Q021Z4gp0 for 20% off any InsideTracker plan.
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