Cohort profile: A longitudinal multi-omics cohort of patients with acute coronary syndrome
Rong Huang, Jie Li, Keqing Hu, Rui Xu, Haitao Yuan, Jiangrong Wang, Mei Gao, Qiang Xiao, Bingqing Dong, Furen Zhang, Fengling Lai, Luxiang Shang, Siyu Hou, Lingjun Tong … See all authors
First published: 03 July 2024 doi.org/10.100...
Citations: 1
Rong Huang and Jie Li contributed equally to this work.
Graphical Abstract
The longitudinal multi-omics cohort of patients with acute coronary syndrome (LM-ACS) is designed as a real-world prospective cohort of patients with ACS requiring coronary angiography. This study aims to enroll 50,000 participants, with a thorough collection of phenotypic data and multi-omics analyses performed on biological samples. Additionally, long-term follow-up will be conducted to track the incidence of major adverse cardiovascular events (MACEs) over the participants' lifetimes. For this purpose, three follow-up scenarios have been established for ACS patients, differentiated based on whether the patients had acute myocardial infarction (AMI) or unstable angina (UA), and whether they underwent percutaneous coronary intervention (PCI) surgery. The LM-ACS cohort seeks to create a unique resource to advance our understanding of the etiology and clinical outcomes of ACS.
Негізгі бет iMetaOmics | A longitudinal multi-omics cohort of patients with acute coronary syndrome
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