Identifying Patients and Tailoring Therapy
Faculty: Karl Doghramji, MD; Paul P. Doghramji, MD, FAAFP
The educational design of this activity addresses the needs of primary care providers (PCPs), sleep specialists, and other clinicians involved in the identification and ongoing treatment of patients with non-24-hour sleep-wake disorder (non-24 disorder). Non-24 disorder is an intrinsic circadian rhythm disorder characterized by cyclic desynchronization between the patient’s endogenous physiologic rhythms and the earth’s 24-hour light/dark cycle. Although most affected individuals are totally blind and completely lack the daily entrainment signal provided by light, recent research has suggested that the disorder is more common than previously appreciated in partially blind patients, and-albeit still rare-in sighted teenagers and young adults. Delays or even complete failures in the diagnosis of non-24 disorder are all too common, in part because patients do not proactively discuss sleep problems with their clinicians. Time-constrained providers also may not specifically probe for the presence of the cardinal symptoms of excessive sleepiness and insomnia, even in high-risk cohorts. Clinicians are further challenged to individualize evidence-based treatment regimens, especially because the recently updated national practice parameters on managing intrinsic circadian rhythm disorders do not fully integrate the only agent that has been approved by the US Food and Drug Administration for the treatment of non-24 disorder. This online Point-of-Care 101 (POC101) program has been built around a 3D animation and lively discussions between 2 sleep medicine experts on the pathophysiologic basis of non-24 disorder, actionable diagnostic recommendations, nonpharmacologic treatment approaches, and the latest evidence for pharmacologic modalities.
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Негізгі бет Improving Outcomes in Non-24-Hour Sleep-Wake Disorder
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