The serotonin hypothesis (or in popular terms, serotonin theory) has been an influential idea since the discovery of the first antidepressant drugs in the 1950s. A recent review article has supposedly debunked the idea that serotonin has anything to do with depression. In this video, I will give my pharmacologists perspective on the topic.
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Additional reading:
The serotonin theory of depression: a systematic umbrella review of the evidence
PMID: 35854107 DOI: 10.1038/s41380-022-01661-0
Expert reaction to a review paper on the ‘serotonin theory of depression’
www.sciencemed...
Background on antidepressant research
helda.helsinki...
Негізгі бет Is the Serotonin Theory of Depression DEBUNKED?
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