A super lecture, very well presented. Thanks Jeannie Lee and iBiology!
@Viz_lifelore
7 ай бұрын
expected to learn more on Mary Lyon's experiments that led her to this groundbreaking conclusion, someone please let me know any source to learn about that!
@000Krim
5 жыл бұрын
This channel is amazing
@aaquib608
4 жыл бұрын
Absolutely
@hannahmich7342
3 жыл бұрын
I find this lecture really informing. I have one from of intersex. During gestation my germ cells failed to fully reach the gonads. Thus one gonad remained as a fetal gonad, ovotestis and an attached germ cell teratoma. Depending on how you define it. My other gonad did develop as a testis but remain small and immature. If that were not enough I have a number of germ cell teratoma found in various areas of my abdomen. Two were removed when I was ten years old and several others were found when I was an adult. These teratoma were 10 cm and 17.5 cm when surgically remove. The 10 cm one happened to also be malignant. I tend to be asexual but also see myself as being transgender.
@hannahmich7342
3 жыл бұрын
@Ismael barrera Interesting! I’ll have to digest this information and do more study
@danchokonstantinov6735
2 жыл бұрын
Great lecture . I always maintained that junk DNA is a false statement of incomplete scientific knowledge. Of interest is if increase in gene expression requires a fine tuning expression , in other words is overexpression of a particular gene beneficial and chronologically determinant.
@xyz9250
Жыл бұрын
If you reactive the inactive X, will it also inactive the previously active X? otherwise wouldn’t it lead imbalance and cause other problems?
@nailamusa5943
Жыл бұрын
Hello mam My question is, the inactivation of x chromosome have any effect on autosomal genes?
@rawaaa3359
2 жыл бұрын
Hello, how could we say in the X-linked inheritance that there is a carrier or pure form if the second x chromosome is inactivated anyway and how the presence of one x chromosome would affect if always the only one X is activated.
@sagarak999
2 жыл бұрын
What an amazing lecture!!
@brentweissert6524
2 жыл бұрын
fascinatiing. When you say that this is something that all mammals do, am i correct in assuming that this does not happen in non mammals, for example, reptiles? if so, why?
@aintnothingbutchickenwing
Ай бұрын
With the references too
@cerberaodollam
5 жыл бұрын
Hmmmm. If inactivation turns us basically into Turners, why do Turners have a recognizable condition? Or they turn off that one by mistake in some cells?
@bearpancakes
5 жыл бұрын
Because there’s control mechanisms, the inactivated X is not turned useless, it is still used to control/balance the active X
@priyankajaikumar
5 жыл бұрын
severe phenotype character are seen in turners due to deficiency in escape genes from silencing.
@OxMxFxG123
5 жыл бұрын
Not all genes are silenced on the inactive X. A bunch of genes escape inactivation.
@thomassahotra7423
5 жыл бұрын
It’s not all inactive still 10% xicst rna but which one gets inactived israndom and it happens in mammals for dosage compensation
@thomassahotra7423
5 жыл бұрын
Does anyone know which x passes down to germ cell during meiosis in females and how this process is reversed
@Dirajmk
Жыл бұрын
thank you
@madhurakamat1656
5 жыл бұрын
Then how are females safe from X linked or sexlinked diseases if this phenomenon occurs? What happens then?
@bearpancakes
5 жыл бұрын
Females can still be affected by X linked diseases but it’s a little more tricky than it seems. If it’s a dominant condition and the affected X is active, the disease will be present; if it’s a recessive condition (only presents in homozygous) then the other unaffected X can compensate for it, and if it’s the unaffected X that’s active the disease will not be present.
@robertogonzalez6083
5 жыл бұрын
@@bearpancakes so in a recessive condition if the unaffected X is silenced then the disease will be present, yea?
@GauravSharma00
3 жыл бұрын
I had the same question, particularly with regard to color-blindness, which, as I understand it, is a X-linked recessive condition. The best explanation that I could come up with in view of what was presented in this lecture, was in terms of the random “mosaic” of activation in the cells of a female. So consider a female having two X-chromosomes, one of which carries the allele for colorblindness and the other carries the normal allele. Because the cells in the female will be a “mosaic” composed of cells in which either one of the X-chromosomes is inactive, about half the cells will have the X-chromosome with the normal allele as the active one, staving off color-blindness (and similarly other X-chromsome linked recessive conditions). Fascinating lecture, but as in much of Biology, generated more questions than it answered!
@ButteredFlied
5 жыл бұрын
My name is Jeannie
@crynotable
4 жыл бұрын
Very nice
@cerberaodollam
5 жыл бұрын
"there are no supernumerary Xes" - with some excepions ;)
@madhurakamat1656
5 жыл бұрын
What about intersex?
@richardwu9013
4 жыл бұрын
Which definition are you talking about?
@iam_google_mai3167
2 жыл бұрын
That why you not advanced in genitc and u will never be until understanding the polarities of these jens
@iam_google_mai3167
2 жыл бұрын
First it's not y x. It's h and small x for what we gain from eating that is important to live your so wrong and I proud to tell
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