To cite: Sugimura N, Li Q, Chu ESH, et al. Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis. Gut 2022;71:2011-2021.
Read the full article here: dx.doi.org/10.1136/gutjnl-2020...
Objective: Using faecal shotgun metagenomic sequencing, we identified the depletion of Lactobacillus gallinarum in patients with colorectal cancer (CRC). We aimed to determine the potential antitumourigenic role of L. gallinarum in colorectal tumourigenesis.
Conclusions: L. gallinarum protects against intestinal tumourigenesis by producing protective metabolites that can promote apoptosis of CRC cells.
Негізгі бет Ғылым және технология Lactobacillus gallinarum, gut microbiota and anti-cancer metabolites
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