Limb formation results from series of epithelial-mesenchymal inductions between the mesenchymal cells of the lateral plate mesoderm and the overlying ectodermal cells. Cells from the lateral plate mesoderm and the myotome migrate to the limb field and proliferate to create the limb bud. The lateral plate cells produce the cartilaginous and skeletal portions of the limb while the myotome cells produce the muscle components. The lateral plate mesodermal cells secrete fibroblast growth factors (FGF7 and FGF10) to induce the overlying ectoderm to form AER.[3] The AER reciprocatively secretes FGF8 and FGF4 which maintains the FGF10 signal and induces proliferation in the mesoderm.[citation needed] The position of FGF10 expression is regulated by Wnt8c in the hindlimb and Wnt2b in the forelimb. The forelimb and the hindlimb are specified by their position along the anterior/posterior axis and possibly by two T-box containing transcription factors: Tbx5 and Tbx4, respectively.[4][5]
@hardcorefishsticks
6 жыл бұрын
my left ear enjoyed your video
@keshavkoshish6467
4 жыл бұрын
Lol
@Smallbutmightywords
4 жыл бұрын
😅😅😅😅mujhe lga meri Earphone khrab ho gyi😂😂😂phir comment dekha😝😝
@Somini5933
3 жыл бұрын
Same here🤭🤭
@noumansaeed7853
3 жыл бұрын
Same 😄left ear enjoy fully
@ambeeshrolta8000
2 жыл бұрын
Your comment helped me to know that my earphones are working well. Thanks 😂
@taniaancyjohn6457
2 жыл бұрын
Thnk u so much Sir..I am an AMRITA student and i m having developemental biology exam tomorrow..i only listened to ur lectures..itz crystal clear ..thnk u so much sir..god bless u
@shomusbiologyofficial
2 жыл бұрын
Thank you so much for appreciating my efforts
@reettata
3 жыл бұрын
My lecturer gave such poor lectures on this subject - you've saved me thank you
@shomusbiologyofficial
3 жыл бұрын
Thank you so much for appreciating my efforts
@abdulsalmansalmankhan601
4 жыл бұрын
Sir u made it simple and easy Thank you
@shomusbiologyofficial
4 жыл бұрын
You're welcome
@kalyaniabburu4873
2 жыл бұрын
Explained very well sir.Full information regarding limb formation.
@shomusbiologyofficial
2 жыл бұрын
Thank you so much for appreciating my efforts
@aesharao4311
3 жыл бұрын
Sir can you please make a video on morphogens and morphogenesis ?
@bengipolat3791
5 жыл бұрын
great video! you always help me a lot!! thanks
@shomusbiologyofficial
5 жыл бұрын
Glad to hear that you are getting benefit from the videos
@manasp5201
7 жыл бұрын
thanks bro for ur video ,that helped me in my exam very much .
@shomusbiologyofficial
7 жыл бұрын
+Manas Ranjan Panda glad it helped
@sbbiswas4
7 жыл бұрын
Thank you sir for such an informative video
@enassamir3274
Жыл бұрын
Please explain relations to hoxa genes
@MissWatermelonify
4 жыл бұрын
Dude, I don't understand anything at all about this stuff, I'm just an illustrator lol. Last time I studied biology was in high school, but a random teacher hired me to do a motion graphics video to help his alumni understand his course, and I just had to look up stuff to be able to know what to draw. I was feeling completely lost until I found this very well-explained video. Thank you so so so so much.
@shomusbiologyofficial
4 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
@axt202
7 жыл бұрын
sir i have a doubt is that limb bud is actually formed from ectoderm?? i studied that it is from mesoderm and the lateral mesoderm and somites move to a region below the ectoderm and proliferate. Thereby a bulge is formed, that pull the ectoderm outward and it is not an outgrowth of ectoderm. Is that correct???
@witty_me
2 жыл бұрын
Tysm
@shomusbiologyofficial
2 жыл бұрын
You're welcome
@imtiazahmad5631
7 жыл бұрын
helpful video. plz do upload videos on muscle, heart and kidney development .
@bijetaroynath8651
7 жыл бұрын
very helpful sir..thank u
@lakshmitilakkarri4706
7 жыл бұрын
Sir Limb is formed from lateral mesoderm??
@Chemistry_4All
7 жыл бұрын
Limb develops from Lateral Plate Mesoderm. Bro you just need to edit the lecture plz. Thanks a ton.
@souvikdas1960
6 жыл бұрын
LPM INDUCES ECTODERM TO FORM LIMB BUD...CHECK WIKI
@cinextravel
7 жыл бұрын
Did u make the Suggestion /Hit map video. I'm unable to find 😣
@kareenaafzal5804
7 жыл бұрын
thanku soo much sir...
@shomusbiologyofficial
7 жыл бұрын
+kareena afzal you're welcome
@kalyanidhruw1706
7 жыл бұрын
helpfull .... thanks
@shomusbiologyofficial
7 жыл бұрын
+kalyani dhruw you're welcome
@niazmughal3394
7 жыл бұрын
thankuuu so much ....😍😍
@fahimalamnobel4789
7 жыл бұрын
sir do u have anylecture on MALT
@kiransharma11111
3 жыл бұрын
Iska pdf mil skta h?? Apka koi telegran h
@akhilaks7597
2 жыл бұрын
Limb is developed from mesoderm, not ectoderm
@saritasharma8470
4 жыл бұрын
Sir there's no sound in this video !!!
@shomusbiologyofficial
4 жыл бұрын
Use both earphones
@pragyaagrawal5663
4 жыл бұрын
Why is the video not audible? Please take care of the audio thing in the upcoming videos.
@shomusbiologyofficial
4 жыл бұрын
It's audible. Use both headphones
@adityapareek5122
7 жыл бұрын
sir I am prepare Csir net but not selected you give me advice
@rifanbudi34
3 жыл бұрын
Human creation in Quran وَلَقَدۡ خَلَقۡنَا ٱلۡإِنسَٰنَ مِن سُلَٰلَةٖ مِّن طِينٖ We have created man from an extract of clay. (Surah Al-Mu'minun, verse 12) ثُمَّ جَعَلۡنَٰهُ نُطۡفَةٗ فِي قَرَارٖ مَّكِينٖ Then We made him a sperm-drop in a firm resting place. (Surah Al-Mu'minun, verse 13) ثُمَّ خَلَقۡنَا ٱلنُّطۡفَةَ عَلَقَةٗ فَخَلَقۡنَا ٱلۡعَلَقَةَ مُضۡغَةٗ فَخَلَقۡنَا ٱلۡمُضۡغَةَ عِظَٰمٗا فَكَسَوۡنَا ٱلۡعِظَٰمَ لَحۡمٗا ثُمَّ أَنشَأۡنَٰهُ خَلۡقًا ءَاخَرَۚ فَتَبَارَكَ ٱللَّهُ أَحۡسَنُ ٱلۡخَٰلِقِينَ Then We turned the sperm-drop into a clot, then We turned the clot into a fetus-lump, then We turned the fetus-lump into bones and We clothed the bones with flesh; thereafter We developed it into another creature. So glorious is Allah, the Best of the creators. (Surah Al-Mu'minun, verse 14) Those are many other version of translation. But understanding arabic langguage is the best way to get the true meaning of the verses. Thanks
@uncleStalin
Жыл бұрын
Can you take your bull shit out of here ?
@dipanwitaghosh6988
7 жыл бұрын
sir please give suggestions for csir net june 2017.plz
@priyalsharma028
7 жыл бұрын
Insufficient information. Did not explain the role of retinoic acid.
@chandanverma5250
5 жыл бұрын
Information was look like given to 10th std students
@meenakshikumari7821
4 жыл бұрын
I think u have no idea about syllabus of 10th standard . Plz check syllabus of 10th standard
@pawanbakthiyal2759
4 жыл бұрын
So much confusing
@shomusbiologyofficial
4 жыл бұрын
Watch it couple of times. The topic is complex
@valentinalazarova4159
2 жыл бұрын
@shomusbiologyofficial
2 жыл бұрын
Thank you
@axt202
7 жыл бұрын
sir i have a doubt is that limb bud is actually formed from ectoderm?? i studied that it is from mesoderm and the lateral mesoderm and somites move to a region below the ectoderm and proliferate. Thereby a bulge is formed, that pull the ectoderm outward and it is not an outgrowth of ectoderm. Is that correct???
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