if we match up the purity with the weight of the final product we got a yield below 5% 💀
@Fluxinate
Жыл бұрын
💀💀
@johndeaux8815
Жыл бұрын
And you said this was how to make tropic acid in the first few seconds 💀
@Iam_summit
Жыл бұрын
💀💀
@user88169
Жыл бұрын
Bruv
@mauricioalpizarrodriguez9078
Жыл бұрын
Could you pls make a video about 1,2-dichloroethane preparation? Im being looking for it to make thiocol polymer, I even tried to make it by the chlorination reaction that's used for benzylchloride but adding anhydrous HCl to boiling ethylene glycol under reflux. I know it can also be made by the chlorination of ethene gas using Cl2 with O2 and iron as catalysts, the problem with is that Im afraid about the reaction because I have no idea if its as dangerous as mixing Cl2 and ethyne 💀
@midwestchem368
Жыл бұрын
"The funnel was gently shaken violently" 🤣🤣🤣🤣 Great video man!
@That_Chemist
Жыл бұрын
Methyl esters are often a lot less stable than their ethyl ester counterpart - they can be far more susceptible to hydrolysis, as an example. This is one reason why you tend to see more commercially available ethyl esters. (they are not always unstable, of course)
@THYZOID
Жыл бұрын
makes sense. hydrolysis won´t be a problem in our case anyways. except maybe in the first step. this might be the reason the yield was so low
@sashboo1370
Жыл бұрын
"The funnel was gently shaken violently" I love it lol. Very cool synthesis, too bad yeilds werent the greatest. Can't wait for atropine!
@PoorMansChemist
Жыл бұрын
Very nice!!! You always do the most interesting stuff. 👍🙂👍
@crabcrab2024
Жыл бұрын
Hmmm… Something tells me we are going to see a synthesis of tropinone in the near future. Great video with interesting chemistry! Thank you, friend. I enjoy them so much.
@GAFUKIS
Жыл бұрын
Fun fact: Another tropane alkaloid you may know is benzoylecgonine, or COCAINE
@eaeis9879
Жыл бұрын
The color is probably due to the resonance of the enolate. Resonance stabilized enolates are often colourful whereas the protonated reactant phenylacetate possesses no resonance. I also think that you should conduct an oxa - Michael addition with benzyl alcohol or sodium benzylate and subsequent hydrogenation to deprotect the ether. I assume that your wet HCl fumes polymerized the acrylate
@chemistry-experiments78
Жыл бұрын
The pink color was similar to the color of a plastic produced from formaldehyde and phenol/resorcinol
@revimfadli4666
Жыл бұрын
I wonder what are the uses for poly(tropic acid)
@georgkiesbauer337
Жыл бұрын
Here some tips for your ether safety (in case you dont already know it): -always test your ether for peroxide before destilling it -if peroxides are present the organikum recommends extracting them with aqueous koh then destillin g( not to dryness) to get some clean ether
@ejkozan
Жыл бұрын
Sodium/Potassium hydroxide destroys peroxides. The same is done by activated alumina. The craziest method I have seen (from Purification of laboratory chemicals, Armarego) is distillation with LAH. A bit wasteful XD
@georgkiesbauer337
Жыл бұрын
Hm interesting, ive always thought that the used base deprotonates the peroxide an thus reduces the solubility of it. But i prophably remember it incorrectly. Using LAH sounds really not fun in combination with ethers xD
@ejkozan
Жыл бұрын
@@georgkiesbauer337 well it destroys peroxides as OO bond is reactive, depending on reagent, you make some alcohols (reduction) some radicals, and msot often tar. For example diethyl ether with peroxide after addition of sodium hydroxide, if content is high enough goes yellow, very yellow, this unhealthy yellow XD
@georgkiesbauer337
Жыл бұрын
Hm that would also explain why it goes yellow :)
@experimental_chemistry
Жыл бұрын
Peroxodizing ethers should always be tested with a sulfuric acidified iodide-starch solution before being heated instead of only trusting in freshly opened bottles...
@chemistryreacts
Жыл бұрын
It was an honest effort!
@EddieTheH
Жыл бұрын
"the funnel was gently shaken violently" 😁 Noice!!! 😁
@maximilianbachler3541
Жыл бұрын
Love one of your suppliers Laboratoriumdiscounter, i use their services as well
@sgtbrown4273
Жыл бұрын
interesting synthesist. A bit over my head but always rewarding to watch.😁
@I_XuMuK_I
Жыл бұрын
Good luck now cheking on that di i-Pr ether for peroxides every few weeks now. That stuff is a bomb xD
@contomo5710
Жыл бұрын
"funnel was gently shaken violently"
@Iam_summit
Жыл бұрын
Very nice
@monoamin_
Жыл бұрын
"Gently shaken violently" lmao
@chanheosican6636
Жыл бұрын
Making synthetic atropine like compounds cool.
@herwew7476
Жыл бұрын
"The funnel was gently shaken violently.." :)
@chemically_literate
Жыл бұрын
Probably should've distilled off DCM before aq. NaOH hydrolysis step. TLC would also be your friend here.
@Alex-ee5pl
Жыл бұрын
Tropinol is pretty interesting too
@hoggif
Жыл бұрын
Silicone tubing is probably a single use item when used with HCl gas. At least the tubing I have has been so and you also seemed to get a leak due to failure.
@defenestrated23
Жыл бұрын
The pinkest reaction I ever ran was a Vilsmeier. I think the iminium ion of DMF derivatives are pinkish, so possibility some short-lived conjugate of DMF and some impurities.
@sixtolavalle343
Жыл бұрын
"i swear to god i was just smoking a cig.. where'd it go i just had it?"
@joemccowan4624
Жыл бұрын
Not many people will get this but from all the trip report channels I've watched I do know that datura tends to make a person believe they are smoking but in reality there was no cig at all lol
@Psychx_
Жыл бұрын
Omg. Das ist genug Atropinsulfat, um einen Patienten mit Organophosphatvergiftung durch den Aufenthalt auf der Intensivstation zu bringen.
@Exotic_Chem_Lab
Жыл бұрын
Cool
@ThopazProductions
Жыл бұрын
Glaucestershire
@asstronix6657
Жыл бұрын
In grocery store there is to get max. 37% Hydrochloric acid! Did you know about a method, to get a higher concentrated smoking acid? I've geared you can do this just with few boxes in a closed box and distilled water! Did you ever tried that method?
@THYZOID
Жыл бұрын
i already showed a method to concentrate HCl but in this video we turned 33% HCl into more or less anhydrous HCl gas. thats basically the highest concentration of HCl you will ever get 99,9%+. regarding aqueous HCl 45% is the highest you can store without blowing up your storage bottle
@bromisovalum8417
Жыл бұрын
I love the smell of diisopropyl ether. Smells much better than diethyl ether.
@Gina-zi2fh
Жыл бұрын
Warum legst du Alufolie über den Magnetrührer? :)
@THYZOID
Жыл бұрын
damit er sauber bleibt
@revimfadli4666
Жыл бұрын
Can it be polymerized?
@THYZOID
Жыл бұрын
it may
@experimental_chemistry
Жыл бұрын
0:40 Still using no measuring glass pipettes... Now you got a big bottle of a reagent that's contaminated with dissolved PS... 🙄
@Iam_summit
Жыл бұрын
Cool
@douro20
Жыл бұрын
Methyl phenylacetate is actually a food ingredient.
@afshinshaloo2489
Жыл бұрын
Please put the tutorial on how to make methadone hydrochloride C21H28ClNO in your channel
@THYZOID
Жыл бұрын
no
@afshinshaloo2489
Жыл бұрын
WHY
@experimental_chemistry
Жыл бұрын
@@afshinshaloo2489illegal
@experimental_chemistry
Жыл бұрын
1:12 Cancer dust...
@yataclysmic
Жыл бұрын
Hi
@igotes
Жыл бұрын
Gently shaken violently? I'd like to see that.
@funnyfails1275
Жыл бұрын
Dude where did you get such an insane amount of Atropine? You could probably kill like 5000 people with this
@THYZOID
Жыл бұрын
we shall never know
@drasiella
Жыл бұрын
🎉Tar🎉🎈
@fmdj
7 ай бұрын
0:25 ahah I know this supplier, they will sell absolutely anything to anyone no questions asked 😅
@THYZOID
7 ай бұрын
new discount code "THYLABS2024" if you want it lol. for some products they want you to fill out an end use declaration though
@fmdj
7 ай бұрын
@@THYZOID the only issue I have with them is that they deliver in packages with "laboratoriumdiscounter" written in large letters on them together with molecules drawings and it raises some eyebrows around me for some reason 😅 I've never seen that form you have to fill in, I haven't dared order too dangerous or really watched chemicals, but I've been surprised by a few things that managed to come through. Thx for the code though, might still come in handy for my nuclear bomb project lol.
@THYZOID
7 ай бұрын
the end use thing is for example required for HF, strychnine nitrate, testosterone, KNO3.....
@fmdj
7 ай бұрын
@@THYZOID ahah KNO3 is sold on Amazon no questions asked, as well as sulphur and charcoal lol, but I understand why a form is asked on laboratoriumdiscounter sometimes
@daisiesofdoom
Жыл бұрын
Could you show us how to make cocaine? For... Scientific purposes...
@GAFUKIS
Жыл бұрын
I thought this was chemolis lol
@MichaelLapore-lk9jz
Жыл бұрын
Das ist gutt!
@andyk939
Жыл бұрын
7000 steps and countless hours to make some slime for... I just don't get chemistry. I'm dumb.
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