Each time I am watching another lecture with Ninja Nerds, my heart fills with so much gratitude. I am sharing them with anyone I know. You are definitely a gift, Professor Zach Murphy, and of course, your entire team. I graduated a while ago, and I am still coming back to these lectures over and over.
@agadooska
6 ай бұрын
NAFLD is now called metabolic dysfunction-associated steatotic liver disease (MASLD), I think we will need to get used to the new term soon.
@pasindusangeeth309
4 ай бұрын
Is it also called MAFLD ?
@BlndDler-zm4mu
5 ай бұрын
keep up the great work, thanks so much this helped so much no doctor in my college could explain it like you. Also love the new format for the lectures
@dennispo4998
Ай бұрын
Hope you can do a deep dive on the most probable cause/s of insulin resistance (IR). I've heard of too much PUFA's causing structural integrity issues on the cell membrane itself; IR is a natural reaction of the body to too much energy availability via cross-inhibition of both FA and glucose use (Randle Cycle); wrong food proportions in the context of too much carbohydrates. Impacts of sleep, stress, meal timing, intermittent fasting, extended fasting, macros in breaking of fast, exercise, etc.
@mostafael-dya4916
6 ай бұрын
Thank you zach and to all your team members for this great effort.
@kalyanirajalingham1286
3 ай бұрын
You're fantastic! Your videos helped a lot! Thank you!!!
@SusanNyambura-f7b
12 күн бұрын
Hi.please return the other previous video of diabetes mellitus...plus the complications
@Traversquip
2 ай бұрын
Thank you🙏. My daughter was dx with T1D at 6 y/o, almost 16 years ago. I never really understood insulin resistance other than our endo. telling us that insulin is unable to process carbs, now I know why! Fast forward to now, she’s graduated from HS, went to Community College, is a Pharmacy Technician, working full time, and has gained ~130 lbs. She has experienced Tachnycardia and has Sleep Apnea, Chrohn’s (currently in remission 🙏🙏). She’s currently taking a GLP1 (haven’t seen a difference ), considering bariatric surgery but she’s so young 😔. But, I don’t see a way to ultimately improving her eating habits. I just can’t get through to her!
@casualonemmo-player2167
5 ай бұрын
Regarding the clogging up inside of the blood vessels... if you loose a lot of weight, and get into a normal bmi range... will most of the clogging get removed by itself? *or is that "damage" permanent?
@Bedlaminhavana
5 ай бұрын
YOU... YOU ARE THE GOD OF PHYSIOLOGY. I'M A FAN.
@JTmoto
6 ай бұрын
Doing a literature review related to MASLD and obviously obesity, this video helped understand the concept way better. ⚕️✨
@peuppeuppeup
5 ай бұрын
thanks for u dedication🎉
@thefallenking1
9 күн бұрын
Really good
@AhmedKhaled-zy6er
4 ай бұрын
You are the best of the best, man !!! 💓
@shahiramohammadi7284
6 ай бұрын
Zach is my super ninja hero 💐💐
@valviv
6 ай бұрын
Great video, thanks Ninja Nerd!
@jbstepke3
2 ай бұрын
You are incredible. How do you remember all of this information. :)
@anjalimaurya_4679
6 ай бұрын
Your video are really helpful to everyone 👏👏💫💫
@serenitysel
5 ай бұрын
Man the new sleeves look so cool!
@judge1694
2 ай бұрын
THANK YOU SO MUCH SIR 🙏🙏🙏🙏
@finncsprivatechannel2215
6 ай бұрын
With regards to meds, antihistamines, especially centrally acting, are a massive cause of fat-specific weight gain and insulin resistance. Drugs like olanzapine will cause the most weight gain owing both to potent D2 and H1 antagonistic effects.
@muqtarjamaegal6071
Ай бұрын
If Metabolic disorder causes Insulin resistance why without exercise cause dm does it have pathophysiology
@TheSeahealth
4 ай бұрын
I really like your explanation, Prof. Zach, especially biochemistry and metabolism, but you have to consider another concept about obesity, namely that it starts with hyperinsulinemia due to high carbohydrates...thank you
@TheSeahealth
4 ай бұрын
not only just calories
@TheSeahealth
4 ай бұрын
how ketogenic diet?
@kiankaveh1158
2 ай бұрын
This is merely a hypothesis called the carbohydrate insulin model which is of high debate in nutritional research and more often than not its been shown to be disproven through clinical trials and inpatient experimental data with metabolic wards and isocaloric diets.
@vincentcyrilliansantoso9858
6 ай бұрын
This is awesome!
@EvelineHendrickson
3 ай бұрын
I am looking for help due to thyroid removal because of cancer, it has been years and still I am overweight, I do not eat any type of sugar includes any type of sugar and carbs, eat only 1 time daily. I just wish I could do something to help myself. I take Unithroid 112mg daily that’s all the meds I take.
@MathiasSnick
19 күн бұрын
Have you consulted an endocrinologist about this? May be an obvious question, but I don't see anyone else who could help you with a treatment plan, your problem is too specific for any other health professional
@brofred7623
6 ай бұрын
Благодарю вас
@subhdrasahu3273
Ай бұрын
Thank u sir 💐
@eveberry9215
4 ай бұрын
thanks ninja nerd
@ok6109
5 ай бұрын
Thanks❤❤❤
@amirabbasbaharfar2328
5 күн бұрын
✅ Done
@sajiruddinsk8129
5 ай бұрын
Allways follow to you.
@Coach_Sooz
5 ай бұрын
I love you
@otuokwulillian9092
2 ай бұрын
❤❤❤
@sanjith1179
6 ай бұрын
6 th like sir, I'm pratheesh from india( tamilnadu).big fan of you sir.say one hii sir.
@billyhw5492
Ай бұрын
Saying that obesity is caused by calories in exceeding calories out is like saying that edema is caused by water in exceeding water out.
@sciencesimplified3890
6 ай бұрын
I think this video should be re-made. There are different theories of the pathophysiology of metabolic syndrome. Many argue excess calories cause hypertrophic adipose tissue to undergo lipolysis, releasing Free fatty acids(FFA) into blood where it enters skeletal muscle (forming DAG which inhibit PKC which inhibit the insulin receptor) and also the high flux of FFA entering the liver up regulates VLDL secretion. The biochemistry defending this has been established in vivo in humans using NMR spectroscopy. Other evidence is the actos medication increases adipose tissues capacity to store FFA, reducing lipolysis and reducing these symptoms, also on the opposite spectrum the disease lipodystrophy reduces adipose tissue capacity to store fat, increasing lipolysis and FFAs entering blood and exacerbates these symptoms. I need to emphasize, im not saying the obesity and FFA theory is dogma, however to say the adipokines are definitively the cause I personally believe is inaccurate and should be emphasized is theoritcal
@sheilaherrera8584
6 ай бұрын
How about you make your own video
@kiankaveh1158
3 ай бұрын
@sheilaherrera8584 never let personal bias of liking Zach get in the way that here are huge debates in energy metabolism and nutritional research mainly the CIM vs CICO. And that there is 100% possibility that any of these theories is plausible
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