Nico Nierenberg, CEO of Persyst, takes us through a demo of the newly released Persyst 15 software using different clinical cases from the EMU and ICU to illustrate the use of different features. Using a 24 hour EMU recording, Nico first describes each individual trend and what it does, including Persyst Spike and Seizure Detection, both of which perform within the same range as a set of expert human readers. At time point 6:25, Nico begins to navigate through the file to discuss how detected seizures appear in the trends. The impact of Artifact Reduction on both the EEG visualization and trend interpretation at seizure onset is shown at time point 8:31. Spike Review is discussed at 11:95. At 11:44, Nico demonstrates how assess individual spikes within a cluster, compare topographic maps of the average or exemplars against customized spike selections, how to visualize propagation maps, create waveform overlays and sort spikes by time, amplitude, perception or similarity. At timepoint 13:30, the utility of the Spike Index Tool is shown using an example file where Electrical Status Epilepticus occurs during sleep (ESES).
Around time point 15:10, Nico switches to an intracranial EEG recording to discuss the new tools Persyst 15 has for iEEG analysis. He discusses semi-automatically generated iEEG montages and how they are used to generate Trends. At 15:51 the iEEG trend panels are discussed for that particular record and the spike activity that can be seen in a particular hardware group. At 16:40 a subclinical seizure can be seen in the Trends and Nico then changes the Trends view to look at the Trends for each individual channel within the hardware groups. The seizure onset is viewed in the Trends and confirmed in the EEG. Nico introduces the new iEEG electrode localization tool at 17:45.
At timepoint 19:25, Nico transitions to discussing cases from the ICU. Spike trends are discussed in the context of example files containing Lateralized Periodic Epileptiform Discharges and Generalized Epileptiform Discharges. Finally, at time point 20:46, the Versus Baseline trend is discussed in more detail using an ICU example case of a patient who was being monitored for changes after suffering a large stroke. Nico shows how the Versus Baseline trend can support reliable recognition of important changes in the EEG that may happen slowly over time and therefore allow for clinical decision making sooner in some cases.
The new Neonatal Seizure Detector is discussed at timepoint 23:38 using an EEG from the NICU. Characteristics of the new Neonatal Seizure Detector are discussed and seizures are seen in both the EEG and the Trends.
Persyst 15 has many more features; this is a broad overview. Thank you for watching and please reach out with questions or comments to support@persyst.com or visit www.persyst.com.
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