YOU ARE VERY GOOD AND DETAILED . THIS IS FOR GRADUATE STUDENTS NOT THE USUALL SIMPLISTIC ONES WE SEE ON KZitem
@avonleastudy6535
Жыл бұрын
Exactly. it is so detailed and easy to comprehend. Thankyou the crux.
@adrijabanerjee-ek6hw
Жыл бұрын
This is for masters and higher studies. Exactly what we need. Amazing Explaination
@physicaleducationrewari3299
5 ай бұрын
Arey Bhai shab gajab h gajab
@方廷安-b6k
2 жыл бұрын
You literally save my biochemistry! Thank You!!!
@YourLocalLeo
Жыл бұрын
quick, clear and concise. great chapter organization, diagrams, everything is great.
@tanvirahmed617
Жыл бұрын
sir you r extremely helpful and so detailed . watching you from bangladesh .
@gabrielatrevino9785
3 жыл бұрын
love these videos! seriously saving my grade in genetics!
@sudhavani4306
2 жыл бұрын
Best vlog on transcription initiation
@mdshanewazhossan1894
3 жыл бұрын
Excellent video brother.
@okpolihenry983
2 жыл бұрын
OH MY GOD!!! , THIS IS IT. YOU GOT MY SUBSCRIPTION
@АннаКопылова-с3д
3 жыл бұрын
your videos are so clear and interesting! thank you so much!!!
@sumaib1
2 жыл бұрын
well prepared and well delivered. I have to appreciate your drawing skills. Thank you.
@AspirantsForum
2 жыл бұрын
Really love this marvellous content and teaching skills. You're lectures are like a beacon. Which textbooks do you recommend us to get such contact in print form?
@claudiamorse
Жыл бұрын
this was absolutely amazing thank you so much
@Audriavbruna
Жыл бұрын
SO HELPFUL MY GOODNESS!! THANK YOU!
@santoshhuded9688
4 жыл бұрын
Nice explanation 👌
@Sweety__Tiwari
2 жыл бұрын
Very helpful, thanks😇
@janvi4589
7 ай бұрын
top content🔥🔥
@islemben4845
Жыл бұрын
Thank you so much , and please what about sigma factor as a specificity factor
@Sunshine-hc3lt
Жыл бұрын
Thank you so much
@MohammedAhmed-pc9ys
3 жыл бұрын
Great work Sir. Well prepared, highly organized lectures with an in-depth explanation. Can you continue your genetics series, please?
@theCrux
3 жыл бұрын
Thank you for the kind words and support. I do plan to continue the genetics series. Are you looking for a specific subject/topic in the genetics series?
@MohammedAhmed-pc9ys
3 жыл бұрын
Thank you Sir 😊. Regarding the suggestion for the genetics lectures, I guess, mutation types and consequences, as a start, will make perfect sense
@theCrux
3 жыл бұрын
Sure, I will put your suggestion on my list.
@ammarahmehak9986
4 жыл бұрын
very nice video, keep it up
@ayeletchenchicheportiche4684
2 жыл бұрын
wow!! so useful!!
@martineneillagateka5779
2 жыл бұрын
May God bless you
@KseniaKlimova
3 жыл бұрын
Thank you so much for such a fantastic and at the same time clear explanation! Much deeper than in an ordinary textbook) Which sources did you use?)
@theCrux
3 жыл бұрын
I am glad you found the content helpful :) I use relevant published articles and peer-reviewed discussions to assemble this content.
@crabjoon
3 ай бұрын
a life save fr!!!
@pratibhasah6698
10 ай бұрын
I hopw u read my comments can u do video on transferrin and its receptor and groES and gro EL.
@theinnominatoidk3821
2 жыл бұрын
Thank you
@Biomeducated
4 жыл бұрын
Made some promo for your channel on my FB page!
@theCrux
4 жыл бұрын
Thank you! I will also set up a Facebook page for my channel so that the information availability/update is more seamless :)
@lucidscience9554
4 жыл бұрын
Thank you for this amazing video!!! I had a doubt here, is base flipping reversed once DNA scrunching proceeds, as in when the bases at -11 and -7 shift upstream of transcription bubble? And is base flipping exclusively observed in the -10 region only?
@theCrux
4 жыл бұрын
Great question! The current understanding is that base flipping is dynamic and reversible once the bubble gets too big - so there is a threshold length of RNA (made during scrunching) that triggers sigma domain 2 to disengage with the TATAAT sequence.
@lucidscience9554
4 жыл бұрын
@@theCrux Got it!!! Thank you so much!
@NabanitaAB
2 жыл бұрын
Please make video on Replication
@theCrux
2 жыл бұрын
DNA replication will be the next major series of videos. I am currently structuring and organizing the content. I hope to post those videos somewhere around March.
@NabanitaAB
2 жыл бұрын
@@theCrux Thanks a lot sir, glad to know that. It'll be very helpful to me just like your previous contents. Your contents are so much interesting and very very informative. I throughly go through all the videos , and those help me a lot. Keep going sir , you're one of the best. 👌🏻 👍🏻
@tanmoydas7095
Жыл бұрын
Sir thank you for the detailed explanation. You told that RNA pol directly binds to UPE for rRNA synthesis, and sigma factor does not bind to this particular UPE(-58,-37). So, does RNA pol for rRNA not need sigma factor?
@theCrux
Жыл бұрын
Hello. I am not sure if I understand your question. In this video we are discussing mRNA synthesis. I don't think this video touches on rRNA. In prokaryotes, UPE is required for typical regulation mechanisms: Example, lac operon: see, kzitem.info/news/bejne/wqB8soabqKeLpYo
@tanmoydas7095
Жыл бұрын
@@theCrux Got it sir. I mis-understood. Thank you
@bioboi4438
2 жыл бұрын
are the elements shaded in purple always there and part of the promoter or only in some certain circumstances?
@harrypal8459
3 жыл бұрын
The initiation by RNA polymerases requires the assembly of a large complex.outline the order of events that result in initiation ,and indicate the type of molecular interactions that are involved in transcription in prokaryotic? Pls reply this question answer in brief and pls plz plz sir reply quickly
@anihysenaj3743
3 жыл бұрын
great video! my doubt: you say ''when the number of nts is greater than 10 the transition from abortive tx to elongation takes place'' but when is it that this happens and why or is it casual?
@theCrux
3 жыл бұрын
Excellent question! 10 nts is sort of a "magic" number (just an average actually and not a strict rule) - when the RNA is synthesized, the exit channel is blocked by the sigma factor, so the enzyme tries to push it out but it fails often. During this failure, the RNA is released, which we call abortive transcript. But after a few tries, the sigma factor is kicked away and the exit channel is cleared out, which allows the RNA to move out and the transition into the elongation occurs. You can find more details in the DNA scrunching part of this video: kzitem.info/news/bejne/mKGc15l_o3urgI4
@anihysenaj3743
3 жыл бұрын
@@theCrux super clear! Thank you very much!
@sammilton6593
4 жыл бұрын
how dna unwinds during elongation in prokaryotes
@theCrux
4 жыл бұрын
Hello Sam! For transcription elongation in prokaryotes, please see this video - kzitem.info/news/bejne/mKGc15l_o3urgI4
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