Lecture on potential risks and adverse of effects of propofol when used as an ICU sedative. These include:
- Propofol can increase risk of muscle weakness and injury
- Propofol may increase risk ICU-acquired weakness
- Propofol is a mitochondrial toxin
- Propofol can promote delirium
- Propofol is in an unhealthy Omega-6 lipid that can cause immunosuppression and hypertriglyceridemia
- Propofol causes zinc deficiency
- Propofol is a potent negative inotrope and vasodilator which can drop heart rate, blood pressure and cardiac output
Discusses alternatives to propofol for ICU sedation
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Негізгі бет Propofol: Panacea, Poison, Propaganda..and Paracelsus! A Dangerous Drug in ICU? Paul Wischmeyer M.D.
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