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prothrombin time/international normalized ratio, PT protime
A prothrombin time (PT) test measures how long it takes for a clot to form in a blood sample. An INR (international normalized ratio) is a type of calculation based on PT test results.
Prothrombin is a protein made by the liver. It is one of several substances known as clotting (coagulation) factors. When you get a cut or other injury that causes bleeding, your clotting factors work together to form a blood clot. Clotting factor levels that are too low can cause you to bleed too much after an injury. Levels that are too high can cause dangerous clots to form in your arteries or veins.
A PT/INR test helps find out if your blood is clotting normally. It also checks to see if a medicine that prevents blood clots is working the way it should.
You may need this test if you are taking warfarin on a regular basis. The test helps make sure you are taking the right dose.
If you are not taking warfarin, you may need this test if you have symptoms of a bleeding or clotting disorder.
Symptoms of a bleeding disorder include:
Unexplained heavy bleeding
Bruising easily
Unusually heavy nose bleeds
Unusually heavy menstrual periods in women
Symptoms of a clotting disorder include:
Leg pain or tenderness
Leg swelling
Redness or red streaks on the legs
Trouble breathing
Cough
Chest pain
Rapid heartbeat
In addition, you may need a PT/INR test if you are scheduled for surgery. It helps make sure your blood is clotting normally, so you won't lose too much blood during the procedure.
If you are not taking warfarin and your INR or prothrombin time results were not normal, it may mean one of the following conditions:
A bleeding disorder, a condition in which the body can't clot blood properly, causing excessive bleeding
A clotting disorder, a condition in which the body forms excessive clots in arteries or veins
Liver disease
Vitamin K deficiency. Vitamin K plays an important role in blood clotting.
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