As someone with a Bioinformatics Minor who always wants to learn more, I cannot express how ecstatic and grateful I am to find your content.- Thank you good sir!!
@donutsandpenguins2839
3 жыл бұрын
Can't believe how lucky I am! I was just considering my options among the hundreds of computer science branches yesterday, and bioinformatics and computational biology was the most interesting one I found. Since it's still new compared to the other branches, there wasn't much I could find out about it. Thanks a lot for the work put into this video!
@DataProfessor
3 жыл бұрын
Glad to hear that! Bioinformatics is certainly an exciting field!
@punkkauz
3 жыл бұрын
@@DataProfessor I wanna know more about bioinformatics, scholarship this and that... would you give some hints
@vidyashreeshinde654
3 жыл бұрын
You are on the right path
@Alecor_studio
3 жыл бұрын
Never in my life would I think I would get a video for this.. There's not many resources on bioinformatics on youtube. This is godsend! Thank you very much.
@DataProfessor
3 жыл бұрын
Thanks for watching! Appreciate the kind words!
@burntchickennugget191
3 жыл бұрын
Ikr its actually really nice. My college doesnt like letting people take courses on codeing in general and are very picky with who can teach it. This is what I wish I had back 10 years ago.
@karthikraja1029
3 жыл бұрын
YEAH IAM TOO
@codelucky
3 жыл бұрын
Can a Machine Learning Engineer(CSE) get into Bioinformatics who did not have Biology at Bachelor's? Can it be consumed via self-learning?
@esmael.c2b
3 жыл бұрын
@@codelucky if you learn in a school, that's learning, if you self-learn, that's also learning.
@emmanuelonah4596
2 жыл бұрын
Thank you professor. It's so heartwarming to have this quality of information shared for free. The best I have seen on Bioinformatics. All my questions answered and opened my eye to the many facets of computational drug modeling and simulation. Thank you once again, Prof.
@joyrainbowdress
2 жыл бұрын
I'm a dentistry student but I love computers as much as I love biology, I also would love to explore the world of clinical research and pharmacovigilance. I think I'd take up bioinformatics in my masters along with my clinical practice, it seems like the best intersection between healthcare and IT.
@ai-ur5uv
2 жыл бұрын
OMG same, I do dentistry and thinking about getting into informatics but not sure because it is very broad and dentitry is usually clinical so very different skill sets
@joyrainbowdress
2 жыл бұрын
@@ai-ur5uv Actually I left my dentistry degree to pursue a bachelors in CS soon after I made that comment, my love for CS surpassed my interest in healthcare. But I hope you can break into informatics!
@wintur2856
2 жыл бұрын
@@joyrainbowdress I'm getting my Computer Science degree aswell. Afterwards, I'll be pursuing a Masters degree in computational biology or bioinformatics. and a Doctorates in Bioinformatics.
@joyrainbowdress
2 жыл бұрын
@@wintur2856 That sounds like such an amazing and well-thought out pathway, I wish you all the best!
@jannmikoingelrabagogamingc6012
2 жыл бұрын
Oh hey! I am so grateful and excited for this one man! I am an upcoming 3rd year BS Pharmacy student and planning to do my undergraduate thesis on this area specifically.
@Teflon2000
3 жыл бұрын
I've study industrial chemistry in college...this video is perfect
@leonardomontes2975
3 жыл бұрын
You are always on top guys! I really appreciate the way you share the knowledge! Thanks Quincy!
@BerkshireHathawayCRE
3 жыл бұрын
I hope you guys can make more bioinformatics videos! Such an important application!
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@paulynamagana7560
3 жыл бұрын
I'm doing my PhD in Pharmacy and I wish I had seen your videos before... I have discovered my love for Bioinformatics, too late to change my PhD tho
@immcguyver07
3 жыл бұрын
Not all of us even have a PhD.
@khanmubeen
3 жыл бұрын
Respected Professor! I'm quite amazed of how you stepped out to share and create such a knowledgeable course for all of us. I love that. 🤗
@TheSsTrike
3 жыл бұрын
Congratulations Data Professor!!!
@DataProfessor
3 жыл бұрын
Thanks Linas!
@scign
2 жыл бұрын
In the deployed app, you should highlight any significant differences in the removed columns since those parts of the fingerprint could be important for pIC50 prediction. This would clearly identify any targets that fall outside the distribution of the training set so the model prediction may be inaccurate. Also, what was the purpose of calculating the Lipinsky descriptors if only the PubChem fingerprint was going to be used in the model?
@ccuny1
3 жыл бұрын
Fantastic. Incredible material on this channel and this is no exception. Thank you.
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@ccuny1
3 жыл бұрын
@@jimcrypto8573 This looks like a scam. freecodecamp, it's your logo but it doesn't look right. You might want to clean this up.
@devpatel2309
11 ай бұрын
why are you just running the code instead of explaining ?
@mahmoudal-bassam2507
11 ай бұрын
This is very helpful! Thank you so much. I tried something like this to compare distribution of normal and -log10 data (import matplotlib.pyplot as plt fig, ax = plt.subplots(ncols=1, nrows=2) df_combined.standard_value.plot.hist(bins=50, ax=ax[0]) df_combined.standard_value.apply(lambda x : -np.log(x)).plot.hist(bins = 50, ax = ax[1]) plt.tight_layout())
@gurudeebanselvaraj8888
3 жыл бұрын
Excellent session. Hats off to you @Data Professor. I really enjoyed the whole lecture. It is quite informative for budding researchers in Bioinformatics.
@aashishkatyal
3 жыл бұрын
Dear Professor, It is always awesome to watch and learn from your sessions. Can you make some video regarding docking by using python?
@nikitamaurya4518
6 ай бұрын
Thank you so much for this project tutorial and for explaining everything in detail. I have completed part 1 and am excited to do all the other parts.
@lo8885
Жыл бұрын
Beginning Part 4 , big clap for all of us Hope to find the thesis subject
@MoonManifesto
Жыл бұрын
Thank you very much Data Professor for sharing the great learning resource!
@prajyotprabhu827
3 жыл бұрын
Excellent!! Much appreciated efforts you folks are putting in. Thank you very much 🙏👍
@gustavojuantorena
3 жыл бұрын
Yeah! Chanin has a great channel!
@DataProfessor
3 жыл бұрын
Thanks Gustavo!
@crismo7753
2 жыл бұрын
Thank You very much for this great tutorial! Sometimes I am asking myself how much do You wish to have a better equipment, but I don't dare to ask You that. I wish You great success and good health!
@johnraviella6561
3 жыл бұрын
Please be advised: We may be able to model using an in vitro dataset, but we can only be inferential insofar as we can given the validity of our premises regarding these in vitro data. Basically what I'm trying to say is that there are unknown mechanisms driving favourable IC50s. Namely, Phospholipidosis has thwarted our computational repurposing efforts against SARS-CoV-2. Thank you for the video all the same.
@DrNoureddinSadawi
2 жыл бұрын
This is a fantastic tutorial, many thanks!
@deeptibhanot762
2 жыл бұрын
Hello Professor, I want to work on parameter tuning of 3D Bioprinters before they print, so it will take input as the tissue type /bone type that we want to print and finally I want to predict the best possible combination of printer parameters for the job. Please help me from where I can get dataset for 3D bioprinted organs as well as dataset of 3D bioprinters.
@hariks6880
2 жыл бұрын
we have studied these in 2014 as Bachelors in bioinformatics (engineering)
@kuldeepkaur-do2ex
5 ай бұрын
How we can retrieve fda drugs data directly from zinc database as well as the biological activity of those drugs? Thank you
@mangalahegde3805
Жыл бұрын
Thank you Professor. I have a doubt. You explained with a example of a target. How can we do the same with multiple targets like all the members of one protein family as targets?
@science_mbg
3 жыл бұрын
Because you did not get any other stardart_type is that you filtered to IC50 only one line before so that is it only unique for IC50.
@indumatisharma3646
3 жыл бұрын
Thanks for this video. Can the model be deployed in RShiny?
@nattawra
3 жыл бұрын
Thank you so much for your wonderful video presentation, this is really helpful !
@tejiyo
3 жыл бұрын
In part 3, Why did you convert the df to .smi file and used command line to apply padel function, can you explain the line " ! bash padel.sh" please
@vishnus5531
3 жыл бұрын
Thanks for this course.... 😍
@danys9085
2 жыл бұрын
Thank you for this amazing video but I wish you could be a bit more specific , I feel sometimes lost
@christianscientist3963
3 жыл бұрын
Since you used the CHEMBL database to look at targets and small molecules in your course, is there a library code to extract Zinc and PubChem drug database to use their small molecule?
@nicolastarquino1061
3 жыл бұрын
Hi Master, thank you for this great video!!!!!!!!! in the minute 46:59 there is a cut that not allow to understand the idea
@OfficialBunnE
2 жыл бұрын
What microphone and camera do you use? 🙂
@militant_dilettante
10 ай бұрын
Thank You for such wonderful lesson! So much useful information, and so tightly packed! I have questions, though. In the beginning of both notebooks for Exploratory Data Analysis we go through the steps to modify the "canonical_smiles" variable, namely, we seem to remove parts of SMILES strings that denote smaller molecules not connected by the covalent bonds (not my area of expertise, not my first language, therefore such an awkward phrasing), and leave in place only the biggest part, probably because it is much more likely to be biologically relevant. Is this step specifically for calculation of the Lipinski's descriptors? Because later we concatenate the descriptors dataframe with the original dataframe. Also, I am doing that lesson more than 2 years after the video was posted, and in the Acetylcholinesterase data ChemBL fed me at least one "standard_value" value of 0. What do You recommend replacing it with: 1 or NaN?
@iii1090
2 жыл бұрын
Hello,Professor,Thank you for your hardworking,could you please inform us whether we can open the same.ipynb as your,or we need to input the code in python or other software.as I am a beginer,so please😄
@fatimzhraannassiri
3 жыл бұрын
that's is interesting thanks a lot!
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@d3v487
3 жыл бұрын
@Data Professor Where do I get the infographic PDF ?
@thedevnoteyt
3 жыл бұрын
Freecodecamp ❤️
@vladislavshevtsov143
2 жыл бұрын
fuсkfreetonight
@LujoSey
9 ай бұрын
Hi Prof, I was following your session closely but I got lost on the mounting of colab after creating the 3 dataframes. Would you please explain the colab jupiter interface for a layman like me? Thanks
@sahebraopawar2754
2 жыл бұрын
great sir... Thank u sir
@Darkslide99
6 ай бұрын
Is the repository still available? It's not showing up?
@nabilnor8710
2 жыл бұрын
Thank you so much 💓💓💓💓
@joshuapatterson7281
3 жыл бұрын
Is there a way to calculate the other fingerprints without downloading padel?
@ahamedalvi1218
3 жыл бұрын
Thanks a lot its a dream come true :)
@ravivishwakarma7865
4 ай бұрын
does any one faced issued while installing rdkit for EDA part. am not able to install this.
@lllll7260
2 жыл бұрын
does the coronavirus target protein in the beginning mean protein that binds to coronavirus? I am confused with that
@sumiharsola6043
3 жыл бұрын
Sir please continue hindi Chanel
@aadarsh8306
3 жыл бұрын
I love u guys Take my virtual love ❤️
@vladislavshevtsov143
2 жыл бұрын
What is virtual love?
@molecule_minds
Жыл бұрын
In part 4 im getting an error. In scatter plot it is showing error like regplot takes from 0 to 1 positional arguments but 2 positional arguments were given
@d13cnpm1_nguyenphuongnam8
3 жыл бұрын
Can you make video about React Native ?
@ayushsrivastava6133
2 жыл бұрын
I don't have any knowledge on ML but I know Python.Is this relevant for me ??
@molecule_minds
Жыл бұрын
how to use our created models? Like i created a model for butrylcholinesterase... how to use it like this app?
@franciscoromogaray3076
10 ай бұрын
How do I access the drive??
@nguyenkaitlyn6364
3 жыл бұрын
why do we have to only select the standard type "IC50"?
@Algo_Simple
3 жыл бұрын
Only so that the bioactivity units are uniform.
@tanohleandreamian2988
3 жыл бұрын
do you have a training course in python for meteorology?
@carjanice
2 жыл бұрын
tf is that for free? Thank you a lot for this content!
@fehmeedamustafa7049
Жыл бұрын
Can we do this using graph data structure?
@allejo7887
3 жыл бұрын
Put subtitles in English for us from other countries to follow, translating the subtitles please !!
@larrysizemore2891
3 жыл бұрын
Can you add this in your resume?
@UwU-uq9pq
3 жыл бұрын
not much explanation for each step and why we need to do that
@nikitamaurya4518
6 ай бұрын
In part 3, I got an empty descriptors_output.csv file, I downloaded the padel zip file from the same given URL on the part 3 Jupyter notebook. Please help. I dedicated a lot of time to understanding and building this project. I don't want to give up now.
@josephoyong3707
Ай бұрын
Hello, Nikki… I'm also working on this project. Can we link up to discuss generally about any challenges faced?
@ilearn.ulearn
Жыл бұрын
Is it just me or does the target search for corona virus code not work? If so, why? I'm having trouble loading the data from ChEMBL. Please help!
@alreadyghosts7727
Жыл бұрын
I just ran it a couple days ago in jupyter notebooks and had no issues. At what point in the video and at what line of code is this happening?
@ameymyakal6059
2 жыл бұрын
Is there good scope for M sc. bioinformatics or M sc. biotechnology ❓️
@jayasuryaviswanath2149
3 жыл бұрын
This is sooo coool
@ItsMyWorld2
3 жыл бұрын
CCNA plz
@phillipsparks9690
Жыл бұрын
Are the data sets available?
@lukecahalane1811
3 жыл бұрын
When I try and display the DataFrame in the data collection section in PyCharm I get a mixture of parentheses and not all the data that is actually present on ChemBl, any help would be appreciated.
@shenglinjing7350
2 жыл бұрын
In part 5, running predictions_test doesn't give any output and if I do np.shape(predictions_test), it returns (0, 4). Do these 2 lines in the original notebook look right? models_train,predictions_train = clf.fit(X_train, X_train, Y_train, Y_train) models_test,predictions_test = clf.fit(X_train, X_test, Y_train, Y_test)
@MoonSahab
2 жыл бұрын
I'm also facing the same issue
@zc7504
2 жыл бұрын
i could not install the libraries from the browser. Could anyone help? I m on Mac
@souldiezcamp2380
3 жыл бұрын
Please how to predict the binding affinity for sequences i have 🙏?
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@ItsMyWorld2
3 жыл бұрын
Networking please
@exco42
3 жыл бұрын
I can't run prediction output area. Error is: ModuleNotFoundError: No module named 'sklearn'. I already tried to pip install -U scikit-learn scipy matplotlib and can't fix the error. Can anyone help?
@abhishekchakraborty3122
3 жыл бұрын
Do we need to know Python in depth for learning this... I've got Bioinformatics in my course curriculum, so got some idea... But not of programming... Please!!
@joelxart
3 жыл бұрын
Many researchers in this field also use R.
@abhishekchakraborty3122
3 жыл бұрын
@@joelxart how can I learn R from scratch if I'm totally noob in programming. Is it possible
@valentinaortiz9935
10 ай бұрын
hahahahahahaah I love the way he justified himself for a little "mistake" he made in the data collection part by saying "I was filming this at midnight" but we can clearly see the time on the screen and it said 5:20pm hahahahahahahh don’t worry you don’t have to justify yourself you are doing us a favour.
@ownSystem
3 жыл бұрын
How about driving cars and how to code that?
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@ownSystem
3 жыл бұрын
@@jimcrypto8573 ethical hacking would be also a cool course thanks again
@robertlogan9733
2 жыл бұрын
Come study bioinformatics with me! enc.edu/program/bioinformatics/
@drsomto007
Жыл бұрын
For people using Windows it gets to a point where this is no longer helpful, some codes like, '! cat molecule.smi | head -5', do not work.
@helloworld2054
3 жыл бұрын
I want to study bioinformatics and I'm currently learning python. So grateful for this course!
@DataProfessor
3 жыл бұрын
Awesome, glad to hear that!
@tilbintt3491
3 жыл бұрын
I have learned Bioinformatics. That was very hard tbh 😰
@helloworld2054
3 жыл бұрын
@@tilbintt3491 oh :/ what do you have to study there?
@tilbintt3491
3 жыл бұрын
@@helloworld2054 I had it in my masters degree. It was more related to Genes and stuff. Analysing gene data was a nightmare for me. I don't remember exactly but different set of genes or data had a different way of approach.
@helloworld2054
3 жыл бұрын
@@tilbintt3491 I see. So what are you doing now?
@clodsire_
3 жыл бұрын
wish this vid came out sooner. i’m about to graduate as a bioinformatics major and i remember struggling so much bc of the lack of online resources and material. whereas you can learn anything online as a swe, you’re completely dependent on school for bioinformatics. to anyone wanting to pursue bioinformatics, it’s a very complex major but if ur passionate about bio, data analysis, and tech then it’s a great choice
@DataProfessor
3 жыл бұрын
Yes, bioinformatics is definitely an exciting field for applying SWE, ML and AI to help make sense of the big biological datasets.
@cj1871
2 жыл бұрын
What would it take for bioinformatics research to become decentralised? Maybe a community funded lab where remote researchers pay to have their experiments run and the results are public which allows other researchers to contribute?
@AJ-qt9hx
2 жыл бұрын
I'm just starting on Bioinformatics after my degree course in Biology. Thank you for putting this video together but this is no beginner course. I'll work on taking some professional course on edX and Coursera, then revert back to this. Thank you sir. ✨👏
@Dankman3
3 жыл бұрын
Im starting a job at Astrazeneca next month. Thank you sir for the course, I will use the knowledge to the best of my ability.
@mr.anonymous6640
3 жыл бұрын
Congrats bro , Wt is ur qualification😅
@Dankman3
3 жыл бұрын
@@mr.anonymous6640 BE Computer Science
@innokirigiti
2 жыл бұрын
Hello, I would also like to know your current qualifications. I am interested in this field
@vasudevkarthik4593
2 жыл бұрын
A tab bit late . But I would like to congratulate you. Hope this ramdan you will get all happiness and good things that you have cherished in life. Peace
@pacifio
3 жыл бұрын
man be expert in biology and computer science while me just being dumb 24/7 epic style
@BayAreaPressurePros
11 ай бұрын
The gethub items are not coming up for me, would you mind maybe uploading them? Other than that, these videos look amazing!!!!! my thesis is bioinformatics heavy and our bioinformatics course on campus is more like an introduction lol. thanks my friend, Cheers.
@miltonkambarami8129
3 жыл бұрын
I am from the Virology side of Bioinformatics and its wonderful to find a Bioinformatics-related tutorial on a computational-based learning platform. I feel Bioinformatics/Computational Biology is starting to embrace more of the Computational side to answer Biological questions and the two are starting to merge as one. Sooner or later Programming is going to be a compulsory skill just like writing but what will matter is types of questions and problems you can solve using programming.
@silvereyes000
2 жыл бұрын
Virology side of bioinformatics? What is it about?
@ai-ur5uv
2 жыл бұрын
@@silvereyes000 probably anlysing viral genomes
@brunobustos96
3 жыл бұрын
Computational neuroscience next please! Love your channel
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@ЭльмарИдрисов-г5э
3 жыл бұрын
Looking forward for "Python for Finance"! :)
@donaldderrick1595
3 жыл бұрын
Algorithmic Trading for finance. on freecodecamp bro
@ЭльмарИдрисов-г5э
3 жыл бұрын
@@donaldderrick1595 , thank you, I will check it out.
@RohitSingh-yo2yl
3 жыл бұрын
ML for finance
@vpundir3024
3 жыл бұрын
It’s very useful for doctors who are learning coding 😼
@jaggyjut
3 жыл бұрын
This is Pure Gold. Thank you for creating this tutorial.
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@bro...5849
3 жыл бұрын
@@jimcrypto8573 no
@e.m.2655
3 жыл бұрын
Been hoping you would make this video! I have a background in biology and a very small bit of experience in informatics.
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@shenglinjing7350
2 жыл бұрын
The latest CDD_ML_Part_1_Bioactivity_Data_Concised.ipynb for part I generates some wrong data for me (NaN values in bioactivity_class, negative LogP values etc.), which gives totally different statistics in Part II if I use that data. However, CDD_ML_Part_1_bioactivity_data.ipynb works fine, and I get the same results as in the video.
@dicegamenetwork
Ай бұрын
Damn that lisp is ROUGH
@azadjain8534
3 жыл бұрын
I was searching for this content for long time. Finally this arrived. Thank you so much for invaluable content.
@DataProfessor
3 жыл бұрын
Awesome, thanks for watching Azad!
@malasharma5512
3 жыл бұрын
Mee too
@0307ismail
3 жыл бұрын
Hi Data Professor, I am doing PhD in Bioinformatics and my research topic is the same as of this video. Thnx alot for this video. I think i will need more of your support and guideline for my research.
@jimcrypto8573
3 жыл бұрын
Thank you for watching, for question, guidance and support at anytime. Just DM Me +1.(.9.1..4). 7..0.4..4.3..3.8..@ W H A T S A P....
@anonymous-tt2lm
2 жыл бұрын
Bio+informatics = new world
@palakgupta8728
2 жыл бұрын
its a great video really helpful. at 14:09 you are not able to see other types of standard type variable because youve already entered its filter as ic 50 so it shows only ic50 entries. once you remove filter.standard type[ic50] , youll see array with inhibition, ki, ec 50, kd, activity.
Пікірлер: 351