He nailed it. If only more people understood how important not eating all the time is.
@davidlissowski5030
Жыл бұрын
Thankyou for the most compelling youtube video for a omad ketogenic/coconut oil lifestyle.. Sending to my doubting 48 year old (myasthenia gravis) daughter, her genetically superior mother, and my genuinely inquisitive gp, who is following this 68 year old guinea pig's 6 month transformation.. One (am) meal a day (23hrs).. Skip tuesdays (47hrs).. Skip first wednesday of every month (71hrs).. Works for me.
@HeleneLouise
Жыл бұрын
I did buy your book and noticed the page explaining ordering overseas. I just received my order today, and took 1 mg about six hours ago. I am enthusiastic about taking Rapamycin. Thank you for your great book
@ModernHealthspan
Жыл бұрын
Renue By Science* 10% Discount Lipo CoQ10: tinyurl.com/2c2pae4w, Glutathione : tinyurl.com/5n7pym2n Use SUBMHS when buying subscriptions for a continued discount of renewal orders Renue By Science* 10% : tinyurl.com/4yrf4tv3 DoNotAge* 10% discount code MODERNHEALTHSPAN tinyurl.com/ycyn9vhn NOVOS* Core & NOVOS Boost $5 off with code MODERNnow5 novoslabs.com/?ref=3957 ProHealth* 10% discount Code MODERN : prohealth.pxf.io/c/3176409/1541296/17976 Bulletproof* 15% off with coupon code: HEALTHSPAN15: tinyurl.com/4npjk5vp ☕If you would like to support our channel, we’d love a coffee…thank you! www.buymeacoffee.com/mhealthspan
@msplateaugal
Жыл бұрын
I ordered some Rapamycin after hearing this speaker tell us how to do it. However, I am not going to try it yet. This is a very powerful drug and I prefer to wait for proper tests to determine dosages, timings, side effects and effectiveness. There is too much guess work right now. Also, the website is for a company based in China. How can we be certain they are producing pure products? Are their products independently tested? I wrote them to find out, but have not had a response. Other companies make certificates available to the public. I was burnt before with a fake NMN supplement sold by a Chinese company and have learned to enquire.
@javadivawithdog
Жыл бұрын
Matt Kauberlin, the lead scientist of the dog aging project, has a human protocol for rapamycin too.
@ModernHealthspan
Жыл бұрын
Hi Thanks for sharing.
@KristerKauppi
Жыл бұрын
Great episode, curious question, do you have any plans on starting taking Rapamycin also?
@franciscunningham1939
Жыл бұрын
Can someone define natural pharmacist, and the qualifications for one to call themselves such?
@ronm6585
Жыл бұрын
Hi Richard. Thanks for sharing this.
@olyav5819
Жыл бұрын
Great interview. Thanks!
@ModernHealthspan
Жыл бұрын
Hi Olya, thanks! Great to see you.
@montypalmer4556
Жыл бұрын
Great info, especially the source option.
@ModernHealthspan
Жыл бұрын
Hi Monty, thanks for your comment.
@montypalmer4556
Жыл бұрын
It's been VERY hard for me to pay for the outside purchases. No crypto, zelle didn't seem to work. The FDA runs a tight ship!
@lawnmower11
Жыл бұрын
Some on the forums recommend grape fruit juice 1-4 hours prior to dosing to increase absorption by 30%
@Pierre-Leloup
Жыл бұрын
Thank you Richard, very interesting and informative interview 👍 I personnaly thought it was a drug to take once in your life at high dosage, not something to take weekly and from what I understand for the rest of your life ? Have you already tried this drug for yourself ?
@ModernHealthspan
Жыл бұрын
Hi Pierre, thanks for your comment. I have not tried it yet, but am seriously thinking about it now. I will certainly talk about it on the channel when I start.
@Saleen099
5 ай бұрын
He encourages people to take this medication, and I would love to, but what doctor is going to give me A prescription for this?
@capnceltblood5347
Жыл бұрын
Any thoughts on The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor? Do you think EGCG can be an alternative to Rapamycin in suppressing Mammalian Target of Rapamycin (mTOR)?
@chuckswadling3318
Жыл бұрын
I am a 53 year old cancer survivor. I started a 3 month trial of Rapamycin at 5mg 1x a week. I am in week 10 and have only noticed a side effect of feeling a coating in my mouth. I am losing weight and very happy so far. My local compounding pharmacy charges me $120 for 90 day supply. What's your opinion of doing this intermittently vs life long? I haven't decided what I should do? I have been in remission for 7 years but still get a SAM shot every 2 months. Sequenced amino acid modulation. I also take 4.5 mg of low dose naltrexone each night before bed. I am in good health and on no other medications except for occasional Ivermectin which is a whole other discussion. Thanks
@javadivawithdog
Жыл бұрын
I was just commenting on this topic today elsewhere on KZitem. You read my mind 😂 Thanks!
@ModernHealthspan
Жыл бұрын
Hi thank you. I hope that you found the video helpful.
@kathya1956
Жыл бұрын
I have 3 autoimmune diseases which I am trying to deal with. Would rapamycin be appropriate for me?
@MichaelMerritt
Жыл бұрын
No one can answer that yet but in general reducing chronic inflammation is good for most auto immune conditions. Pulsed weekly dosing is important, not daily. There has been some limited studies on rapa being helpful for RA, if you google it.
@grahamswett6430
6 ай бұрын
Been taking it for years to address autoimmune dysfunction that caused joint pain. I’m am free from almost all pain. I also do OMAD and a lot of aerobic exercise. Have never felt better other than I am getting older. Can rarely get my heart rate to 180 on a strenuous cycling event any longer. Not going to live forever- yet….
@virgilkirschner5717
Жыл бұрын
Anyone have any problems with ordering from the anti-aging store in Hong Kong? Thank you
@melanie.3837
Жыл бұрын
This is very interesting. You mentioned that intermittent fasting works as well and I am wondering whether intermittent fasting is just as good as using Rapamycin to slow aging?
@HeleneLouise
Жыл бұрын
I have read about this. I don't think it's exactly the same, but fasting is definitely very good for longevity and health. My understanding is it would be best to use both intermittent fasting and Rapamycin.
@melanie.3837
Жыл бұрын
@@HeleneLouise Thanks! Good to know. I wonder why some have mentioned that Rapamycin may also raise lipids and cause insulin issues. I don't want to fix one problem only to create another and wonder whether or not this is accurate.
@HeleneLouise
Жыл бұрын
@@melanie.3837 I actually haven't heard about Rapamycin raising lipid or causing insulin issues. I don't dispute that, I just don't know. As far as lipids, I've never worried at all about cholesterol because I think the science on it being harmful is flawed research. I would be concerned about high triglycerides. I would not like to cause insulin issues. But I had an odd experience with fasting a couple of years ago too. I decided to fast four days a week for twenty six weeks. Well, I was too fasted out to go more than 12 weeks, not surprisingly. I was trying to copy a mouse study where they had ruined the pancreases of these poor little mice, and then put them on the 4 day a week, 26 week fast, and they all regrew normal pancreases. It was as if they had pancreas transplants. But the weird part for me was that my fasting glucose when I did this went up to near diabetic levels. So the bottom line is, that either method could have side effects. My glucose went back to normal after a while. I personally think the Rapamycin is worth trying. Still, there is a whole lot of benefit in fasting.
@HeleneLouise
Жыл бұрын
@@melanie.3837 Hi Melanie. I wanted to add a couple of thoughts to my response to you from yesterday after giving it more thought. There is a well known Rapamycin researcher, Mikhail Blagosklonny, that has written about side effect of using Rapamycin for anti-aging. He pointed out that the side effects that are reported such as raising lipids and insulin issues are taken from patients using larger daily doses for prevention of organ transplant rejection. The once a week smaller doses taken for anti-aging did not show these side effects. In fact, his feeling is that NOT taking Rapamycin is "more dangerous than smoking." I thought I might also mention my own experience with diet and fasting. Fasting has been used for centuries in the treatment of epilepsy. In the 1920s the ketogenic diet was formulated to mimic fasting so that the fasting effect could be longer duration. Having been developed for the treatment of epilepsy by fasting mimicking, the keto diet was and is extremely successful in controlling epilepsy. Being akin to fasting, it also has many of the health benefits of fasting. So, point being, it might be of interest to you. And also, I think both Rapamycin and fasting and keto diets are great ways of improving health and longevity. As far as studies, people are so long lived that most of the evidence for longevity is anecdotal. I am just starting on Sirolimus, which is generic Rapamycin, and I'm surprised to notice immediate benefits. And I have fasted and keto dieted in addition. But, most of the people I've heard talk about Rapamycin do recommend medical oversight, like lab testing.
@AzTahirMD
Жыл бұрын
Where I can find doctor in US give me Rapamycine ? Please help
@michael-qp9xd
Жыл бұрын
For blood testing Dr. Ross mentions on checking for levels - one hour, two hours, 8 hrs after taking 5/6 gram dose? What is best timing for blood draw?
@ddutton4716
Жыл бұрын
Not gram but milligram.
@espinosalexis
Жыл бұрын
Yes, what is the right timing and the corresponding target levels in blood?
@ModernHealthspan
Жыл бұрын
Hi Michael, thanks for your question and that is a good point and I did not ask specifically. The numbers he was talking about were in the nanograms per ml which would be the residual levels and since he did not say directly after taking rapamycin then I think it looks like residual levels. It depends if you are checking, am I taking enough to be effective (I would think you need the test shortly after taking rapamycin to see what the peak is) or am I taking too much (where I think you would want to look at the residual levels as you don't want it interfering with mTOR all the time.)
@espinosalexis
Жыл бұрын
@@ModernHealthspan Great points you make! Try to catch the peak to tweak dosage and to catch the residual to tweak the frequency.
@SquatFull
Жыл бұрын
Rapamycin is a potent and selective inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, which acts as a central integrator of nutrient signaling pathways. mTor is a key regulator in maintaining skeletal muscle mass. Rapamycin is an inhibitor of mTOR and mTOR is critical to signaling muscle protein synthesis. Why would rapamycin be used as an anti-aging agent that inhibits muscle protein synthesis? Would resistance muscle training to maintain muscle mass be impaired and cause sarcopenis muscle atrophy?
@Always-xl9db
7 ай бұрын
I am trying very hard to find an answer to this same question. Plz let me know if u have any update on this. What I gathered so far is that although it doesnt improve muscle gain, it helps with muscle “quality” through mediating more efficient mitochondria and ATP production.
@ModernHealthspan
Жыл бұрын
Magnesium Breakthrough 10% Discount bit.ly/3O5tPfu with code Modern10 Renue By Science NMN, 10% discount: tinyurl.com/5n8z97vz Use SUBMHS when buying subscriptions for a continued discount of renewal orders Renue By Science 10% : tinyurl.com/4yrf4tv3 DoNotAge 10% discount code MODERNHEALTHSPAN donotage.org/products/ NOVOS Core & NOVOS Boost $5 off with code MODERNnow5 novoslabs.com/?ref=3957 ProHealth 10% discount Code MODERN : prohealth.pxf.io/c/3176409/1541296/17976 Dr Ross Pelton Playlist : kzitem.info/door/PLkfzM7KJv6vbe7sYwXdSuILCX2-lFRV6m
@michael-qp9xd
Жыл бұрын
What amount does Dr Ross supplement with lithium? Also read other doctors take lithium orathate version. More side effects with aspartate version.
@ModernHealthspan
Жыл бұрын
Hi Michael, thanks for your question. He said a "low dose" but I did not ask exactly how much. We did speak with Dr Guttuso on lithium and he talks in quite detail about the various doses. Supplemental (as opposed to clinical) seems to normally be in the 1 to 5mg range.
@cactuscanine3531
Жыл бұрын
Take 1 gm a day. Do not take high dose amounts as this can cause Lithium toxicity.
@Montie-Adkins
Жыл бұрын
I'd like to know of people who ordered with International Anti Aging Systems and what their experience was.
@ModernHealthspan
Жыл бұрын
Hi Monte, thanks for your question. I am thinking of ordering from them and will update if and when I do.
@Montie-Adkins
Жыл бұрын
@@ModernHealthspan When you get them, can you take them to a lab of some sort and see if they can tell you if the product is the real deal?
@mangostickyrice555
6 ай бұрын
Thumbs up 👍
@michael-qp9xd
Жыл бұрын
With several generics - which found to be best for consistent quality and best for consistent absorption - any information on this?
@babaluto
Жыл бұрын
My wife and I took a chance on a supplier from India. 500 x 1 mg tabs for $300 delivered. At 6 mg a week, I definitely feel it. It does mess with my blood sugar and being type 1 diabetic, I have been able to figure out a management protocol. Going in Monday to draw blood for a level check. Anecdotally, I do attest to these pills from India are the real deal. I would be happy to share details of you PM me. YT blocks that stuff here. Cheers!
@ModernHealthspan
Жыл бұрын
Hi Michael, thanks for your question and please if anyone has experience jump in! I am thinking of trying the one, rapapro, suggested by Dr Pelton.
@manuelojeda9144
Жыл бұрын
It's amazing that explanation. My Great-grandmother lived to be 103 and according to my Dad never went to a doctor, and she didn't have any old AGE disease that this generation is suffering.❤❤❤❤
@javadivawithdog
Жыл бұрын
My grandmother lived to be 103, too. She was never sick. Her children always remarked on this.
@pilatesfitness8766
Жыл бұрын
neither did my great-grandma. At some point, she decided it was a good time to depart the Earth. Cause of death: "old age", there was absolutely nothing wrong with her.
@alaneverett9767
Жыл бұрын
I assume you're from the United States as most of the rest of the developed world gives it's citzens coverage. Anyone in the United States can get affordable health insurance by going to the Health Insurance Marketplace as long as your yearly income is over aooriximately $12,800. When you make your application they will give you a quote that is in the $600 to $800 per month range depending on which policy you choose. After that look around at the bottom of the page there'll be a place to apply for a subsidy. I know people who are paying less than $10 a month for their insurance. The subsidy is a sliding scale and if you're making more than $60,000 a year for a single person than the subsidies slowly goes away the higher your income is. Beware and do not buy these junk insurance policies but ones that are rated like platinum or Sapphire or silver. You can always call the health insurance Marketplace number and talk to a licensed health insurance person and they can help you pick out one that may be good for you. For example some policies have better coverage for drug abuse issues than others. At the very least you ought to get a high-deductible policy that would kick in after $10,000 or $20,000 in case you became seriously ill or injured in an accident.
@Charity-l5g
6 ай бұрын
Biological aging is not about how many years you have lived. It's about how many poisons you have stuffed into your body: fructose, seed oils, rapamycin...
@prewest13
8 ай бұрын
Why not test yourself after 3 days to see the peaked plasma level of the drug? Why wait till day 6 are 7 when the drug is cleared. The Half life of the drug is 62 hours. So on day 7 it should have gone through 3 half-life
@tedschwartz2142
Жыл бұрын
does any one know where to get this drug ..
@bluecurlygirl
Жыл бұрын
By the sounds of things you need a prescription from your doc as it is used to treat certain conditions so it's a recognised drug.
@tedschwartz2142
Жыл бұрын
@@bluecurlygirl i know but my doctor refues to give one ..
@dcjohnson2208
Жыл бұрын
@@tedschwartz2142change doctors
@javadivawithdog
Жыл бұрын
@@dcjohnson2208easier said than done. I think if there is no justification for prescribing the medication most ethical providers would not do it. Too many risks to rapamycin.
@DYPIUS_IS_ON_COINBASE
Жыл бұрын
@@dcjohnson2208how did you get it?
@manuelojeda9144
Жыл бұрын
I TELL that to my OIANO STUDENTS.
@manuelojeda9144
Жыл бұрын
Piano
@manuelojeda9144
Жыл бұрын
I've been taking Magnesium BREAKTHROUGH FOR MONTHS . MY wife takes MAGTECH a magnesium COMPLEX.❤
@ModernHealthspan
Жыл бұрын
Hi Manuel , thanks for sharing. I hope that it is working for you and your students.
@nerin3624
Жыл бұрын
Where is safe to obtain rapamycin?
@ModernHealthspan
Жыл бұрын
Hi Nerin, thanks for your question. Dr Pelton talks about this from 29:15 onwards. I have also added a link to the website that he mentions.
@arhu74
Жыл бұрын
Supposedly the stuff from India market is real (unlike the Chinese stuff) but you need to get it imported . I have no experience with importing as I just write my own prescription
@nordoflobsquipple3121
Жыл бұрын
At one time, dogs did not develop the same diseases and humans. That only began when pet food companies began adding grain, fruit and vegetables to dog food.
@msplateaugal
Жыл бұрын
@ModernHealthspan Hi Richard, I have read about Rapamycin many times, but was blocked by the need for a prescription. I have finally found a source. Pelton’s book is a paperback and sells for $125, so I will opt out. I note that he has a PhD, not an MD. His consultation fees of $200/hour are more inline with those of an MD. I know the world of celebrated PhDs in academia and $200/hr is unheard of. -Jenny
@msplateaugal
Жыл бұрын
His book is a paperback and sells for $125!
@msplateaugal
Жыл бұрын
@@javadivawithdog He also charges $200/hour for consultations. He has a PhD, not an MD. I am walking away. There are others.
@javadivawithdog
Жыл бұрын
@@msplateaugalI think that is PharmD?
@javadivawithdog
Жыл бұрын
@@msplateaugalUnderstand. The concept of the company is interesting. A typical medical visit would be $200 or more if you paid for it without insurance. If someone has an HSA that would be a way to pay for this as an example.
@javadivawithdog
Жыл бұрын
Also one's age is a factor to consider in starting. Don't start under age 40. Probably no need.
@mats8038
Жыл бұрын
Well ancestors had shorter life span right? Maybe you should not refere to the ancestors with much shorter life span and this mtor.
@juicebox853
5 ай бұрын
Pelton makes a lot of unsubstantiated claims and recommendations.
@kekceo3942
Жыл бұрын
Here's the side effects: Accumulation of pus anxiousness, unexplained backache black or red, tarry stools bleeding from the gums or nose blurred vision body aches or pain bone pain bruising burning or stinging of the skin burning while urinating burning, dry, or itching eyes burning, tingling, numbness, or pain in the hands, arms, feet, or legs change in mental status changes in skin color chest pain chills confusion cough dark or bloody urine deafness decreased urine output decreased vision difficulty with breathing or swallowing dilated neck veins discharge from the eyes dizziness drowsiness dry mouth earache excessive tearing eye pain facial hair growth in females faintness or lightheadedness when getting up from lying or sitting position fast, slow, or irregular heartbeat fever flushing or redness of the skin, especially on the face and neck general feeling of discomfort or illness increased hunger increased menstrual flow or vaginal bleeding itching, pain, redness, swelling, tenderness, or warmth on the skin lack or loss of appetite large, flat, blue, or purplish patches in the skin loss of sexual ability, desire, drive, or performance loss of voice muscle pain nasal congestion nausea or vomiting numbness or tingling around the lips, hands, or feet pain in the chest, groin, or legs, especially the calves painful cold sores or blisters on the lips, nose, eyes, or genitals pale skin prolonged bleeding from cuts rapid heartbeat rash red or dark brown urine redness or swelling in the ear redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid ringing in the ears runny nose seizures sensation of pins and needles severe constipation severe vomiting severe, sudden headache slurred speech sore throat sores or white spots on the lips or in the mouth stomach cramps, pain, or upset sudden decrease in the amount of urine sudden loss of coordination sudden, severe weakness or numbness in the arm or leg sweating swollen, painful, or tender lymph glands in the neck, armpit, or groin tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area tremor ulcers on the lips or in the mouth unusual tiredness or weakness vision changes weakness or heaviness of the legs white patches in the mouth or on the tongue yellow skin and eyes Less common Bloating change in size, shape, or color of existing mole hoarseness mole that leaks fluid or bleeds new mole pains in the stomach, side or abdomen, possibly radiating to the back skin ulcer or sores Incidence not known Abnormal wound healing headache hives or itching large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs nails loose or detached puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue swelling of the arms or legs yellow nails lacking a cuticle Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Abnormal vision acne belching blistering, crusting, irritation, itching, or reddening of the skin burning feeling in the chest or stomach burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feeling constipation continuing ringing or buzzing or other unexplained noise in the ears cracked, dry, or scaly skin crying decrease in frequency of urination degenerative disease of the joint depersonalization diarrhea difficulty with moving difficulty with passing urine (dribbling) dysphoria ear pain enlarged abdomen or stomach euphoria excess air or gas in the stomach or intestines excessive muscle tone, muscle tension or tightness fear feeling sad or empty hearing loss heartburn inability to have or keep an erection increase in heart rate increased hair growth, especially on the face increased urge to urinate during the night indigestion irritation in the mouth joint pain or swelling leg cramps loss of bladder control loss of energy or weakness loss of interest or pleasure loss of strength lower abdominal or stomach pain muscle aches, pain, stiffness, or weakness nervousness pain in the back, ribs, arms, or legs pain or burning in the throat pain or tenderness around the eyes and cheekbones paranoia pelvic pain quick to react or overreact emotionally rapid breathing rapidly changing moods inflammation, redness, or swelling of the gums or mouth shaking or trembling shivering sleepiness sunken eyes swelling swelling of the scrotum tender or enlarged gums tenderness in the stomach area thickening of the skin trouble concentrating trouble sleeping waking to urinate at night
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