So agonists and antagonists actually only bind a subset of the receptors the natural ligand binds?! Confusing? Sure is! This video is meant to help you understand how receptor selectivity is related to the organ or system specificity of any given drug.
I'll also remind you about the CHOLINERGIC nicotinic acetylcholine receptors in skeletal muscle, and introduce you to the CHOLINERGIC muscarinic receptors in autonomic (parasympathetic) target organs.
WOOHOO!
PS: You've already been introduced to some ADRENERGIC (autonomic sympathetic) receptor subtypes: alpha-1, beta-1 and beta-2. Awesome! Now you know about adrenergic (sympathetic) and cholinergic (parasympathetic) drugs even though you haven't learned any drug names yet. Just wait until week three! WOOHOO!
Disclaimer: This video is intended as an introduction to pharmacology for pre-nursing, pre-PA, pre-pharm and pre-med and other students interested in pursuing a career in patient care. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician with any questions you may have regarding a medical condition. If you are a pharm student then I realize I probably am annoying the heck out of you by using selectivity and specificity without perfect precision. Meh.
"Ode to Joy" by Ludwig "Two Sheds" Beethoven. Other music by TaiChiKnees.
Негізгі бет Фильм және анимация Receptor Subtypes and Selectivity - Example: Cholinergic Receptors
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