Im paying 9 grand a year for uni and I prefer watching your lectures which you give out for free, you are amazing !
@randyszymkowski882
4 жыл бұрын
I'm retired, and if I won the lottery, I would go back to school and study health sciences. I spend the better part of my spare time watching microbiology, anatomy & physiology, pharmacology, pathology, biochemistry etc. etc. etc. lectures and demonstration videos. In the past two and a half years I must have about three thousand pages of notes. IT ALL COSTS ME NOTHING! I cannot understand for the life of me, with the technology we have, why an education costs a king's ransom. A handful of people at the top of the educational hierarchical pyramid are stiffing the majority at the bottom.
@marionyah5548
7 жыл бұрын
You are the best! You deserve many many more subscribers!
@kamalikaray5718
4 жыл бұрын
You are the master of entire biochemistry. Thank you sir.
@larisajover8968
6 жыл бұрын
You saved my life man!
@jasmineestrada2190
Жыл бұрын
Love the way you explain concepts. So clear. Thank you so much for this
@ABCXYZ-hr5rk
6 жыл бұрын
extremely conceptual good job sir
@sikoncembu3904
8 жыл бұрын
thank you..ur such a very good teacher..i have fully understood ur explanation..AK lectures are best!!
@schibli84
6 жыл бұрын
great video, will definitely donate once I have a job
@joannbrown9158
8 жыл бұрын
Thank you. You are so clear and accurate.
@mcjester1523
3 жыл бұрын
really clear and concise good stuff man
@artofnature2796
7 жыл бұрын
One of my favourite teachers
@kennethlopez6334
2 жыл бұрын
my professor said you can also regulate step 1 of the TCA cycle.... citrate synthase can be inhibited by ATP, NADH, and succinyl CoA.. I guess its just a difference in textbooks
@s95175364
7 жыл бұрын
You make clear points :) Thank you!
@brain.wavves
10 ай бұрын
u are a lifesaver. thank you for clarifying these difficult concepts for MCAT studying!
@jamesleroy572
Жыл бұрын
Just wanted to pop in and say thank you for these videos.
@socialgrowthclub
5 жыл бұрын
Thank you very much for the wonderful video. It is very educative
@yihan8274
6 жыл бұрын
How can a lecturer be so fking AMAZING!!!!!!!!
@daniels2659
7 жыл бұрын
In step 4, for a-ketoglutarate dehydrogenase, at 10:40, it is CoA-SH that is oxidized, rather than a-ketoglutarate
@SubeeKarma
7 жыл бұрын
Hello there Mr. AK. Great job as always. Want to thank you and congratulate you on wonderful content. One more thing and maybe I am mistaken but I thought I read somewhere that citrate synthase is regulated too.
@ogn8343
7 жыл бұрын
yes not just that but also the whole TCA cycle is regulated even by the conversion of the pyruvate to acetyl CoA whiich is very imp. step since it determines the flux of the whole cycle and this regulation take place by regulate the pyrruvate dehydrogenase thru. its 3 main subunits E1,E2 and E3
@bilalabusubaih1857
7 жыл бұрын
thank yoooouuu you are the best
@Shersify
7 жыл бұрын
THANK YOU SO MUCH
@studyl0pez
8 жыл бұрын
Hi, Love the video and all other video are amazing. One question couldn't you regulate the TCA cycle the same way with the citrate synthase via similar mechanism.
@ogwangrobertrapsy3586
6 жыл бұрын
Good work Master
@ac4190
4 жыл бұрын
According to Principles of Biochemistry by Moran et al., citrate synthase is inhibited by ATP in vitro. Still, changes in ATP concentration are unlikely to affect citrate synthase in vivo. Some bacteria c. synthases are activated by alpha-ketoglutarate and inhibited by NADH. Knowing that your comment was posted 3 years ago, I hope it might be useful for anybody else browsing through.
@howlscastle3136
5 жыл бұрын
Thank you so much
@KIM-ml8vs
7 жыл бұрын
Thank you !!!!
@18arnabghosh53
4 жыл бұрын
Very nice
@kennethlopez6334
2 жыл бұрын
you are the goat
@robinbhuiyan244
6 жыл бұрын
tnx a lot
@habibiallah-6783
3 жыл бұрын
12:21 for the screenshot!
@hossainadamzad5907
11 ай бұрын
That is typical of Muslims
@Philosophy-vg6ry
Жыл бұрын
Mr. Andre please take all my money
@mymcattutor9195
6 жыл бұрын
At 8:43 when he says ADP produces a positive feedback loop by enhancing the affinity of isocirate dehydrogenase, thus increasing the production of ATP wouldn't this be a negative feedback loop? More ADP triggers a cascade that increases ATP?
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