This is amazing!! I'm have zero intuition for biophysiology but you made it as clear as glass. Thanks for breaking it down into baby steps!! Love your simple but comprehensive diagrams.
@yousifalhadithi1964
6 жыл бұрын
i never understood the resting memb. potential but now ... i still don't understand it
@samiras6962
5 жыл бұрын
mohammed just memorize it 🤷🏽♀️
@Apratim98
5 жыл бұрын
I know its fucking confusing, bcoz no one is starting it frm the basic, i have made video too on the same topic, watch it once i hope it will help you..and pls comment if it does..or any doubt..
@rania7801
5 жыл бұрын
@@Apratim98 Thank you! I just checked out your video and it was really helpful! Thankfully I checked the replies.
@sabett198x
5 жыл бұрын
Lol, We are on the same boat Mohammed... and I can’t memorize something that I don’t have a basic understanding of...
@aleidaortiz4599
5 жыл бұрын
Me too
@mauriciosujo1999
7 жыл бұрын
Wow, you make everything SO simple. i was stuck on a couple concepts here, clear 100%!
@LittleBear2007
4 жыл бұрын
I find your Osmosis is so clear and easy to remember. I want to be a part of your osmosis. Can't i?
@AbcdEfg-yj9vv
9 ай бұрын
Only video across globe that clearly explains resting membrane potential and equilibrium potential. Thank you sir 😊
@osmosis
9 ай бұрын
Happy to help 💖
@charlessantosti
7 жыл бұрын
Great, I had been waiting on Physiology from Osmosis for a long time! Thank you!
@Jen_nyy13
4 жыл бұрын
Very helpful thank you! Its hard teaching yourself this when you are taking online classes because of this quarentine
@shashankpahariya
4 жыл бұрын
Hii
@vaevoe6272
2 жыл бұрын
my prof has a PhD in neuroscience from harvard and ive listened to him explain this numerous times and never understood it but this video made me understand it finally. ty
@osmosis
2 жыл бұрын
Wow! We're glad that our video was able to help! 🙏🏼 ❤️ 😊
@SummedUp
6 жыл бұрын
That was a great piece of work!
@gunnerprinceton9726
3 жыл бұрын
pro trick : watch series on flixzone. I've been using them for watching all kinds of movies these days.
@arthurwesley7444
3 жыл бұрын
@Gunner Princeton Yea, have been using flixzone} for since november myself :D
@judahcallum8504
3 жыл бұрын
@Gunner Princeton yea, I've been watching on flixzone} for since december myself :)
@ilaila3504
Жыл бұрын
This video seemed so simple, I was brand new to this formula a couple of weeks ago. So I kept watching it, but once i slowed the speed right down - then it started kicking in! thank you so much!
@osmosis
Жыл бұрын
Most welcome! 😊
@brentgroen3204
8 ай бұрын
this is so great, the book i used just glances over most of this to jump to the action potentail. and i was struggeling to understand how the consentration and charges worked.
@osmosis
7 ай бұрын
Thanks! 🙏🏼
@ZaynabAhmed-vf7fd
6 ай бұрын
you're the best, explained it better than my uni professors
@osmosis
6 ай бұрын
Thanks for the feedback! 🙌🏼
@irispanagoulopoulou
4 ай бұрын
Brilliant video! Thank you very very much!
@osmosis
4 ай бұрын
You're very welcome! 😊
@RealSSTELLA
4 жыл бұрын
best video I've seen on ionic basis of resting potentials! thank you, I've been searching and this one is the easiest to follow along and explains the equations/gradients the best
@erikplumeda1299
4 жыл бұрын
This helped SO MUCH, especially during COVD-19 where learning things on your own from the university is a bit more difficult to understand on your own, when someone is not lecturing these bulky ideas to you. Great Video!
@nzzuraki991
4 жыл бұрын
Erik Plumeda so true
@sevgilikitaplarm4364
3 ай бұрын
This was really helpful.
@osmosis
3 ай бұрын
That's nice to know! 💕
@l883l
7 жыл бұрын
osmosis! this video is brilliant !! I've read about this topic from endless sources but I've never felt until now that I've truly grasped the concept. Thank you so much for your work. I've watched at least 90% of your pathology videos and honestly After Robbins and Porth you have made my life so much easier! thank you
@osmosis
7 жыл бұрын
Thanks so much! It would be awesome if you and your friends could review us on our Facebook page. facebook.com/pg/OsmoseIt
@aoifewest
6 жыл бұрын
for the first time i understood. thank you.
@nehakakde3785
7 жыл бұрын
I lkie the way he explains and the presentation is always very nice to watch n clear .
@osmosis
7 жыл бұрын
Thanks, Neha! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZitem? Check it out here: bit.ly/2u35D6J
@firaolhabtamu703
2 жыл бұрын
Thanks you saved me a lot of time.
@BoshraAsadi-jx2gc
4 ай бұрын
Thank you so much. 2024 and video is one of the most helpful lessons 😍😍😍
@osmosis
4 ай бұрын
Glad it was helpful! ❤️
@MrBeachwaves
4 жыл бұрын
Thanks for another great video! Would have preferred a more conceptual rather than a mathematical explanation though, as well as an explanation of the role of the NaKATP pump and its contribution to the resting membrane potential.
@dannichols6261
4 жыл бұрын
Yes, I agree, it's not so good to just *mention* the Na/K pump, and then say nothing *about* it! I think it simplifies to: the Na/K pump helps maintain the *concentration gradient* , while the *leak channels*, in relation to *both* the concentration gradient *and* the (sort-of opposing) electrostatic gradient, are what balance out to yield the resting membrane potential.
@rababbashir78
3 жыл бұрын
You really deserve subscription
@osmosis
3 жыл бұрын
Thanks for this feedback!
@dimemo2023
5 жыл бұрын
You made it quite clear! Thanks!
@mustafadonmez7595
7 жыл бұрын
woww you start physio, Thank of billions...
@raghadalomari4058
7 жыл бұрын
this is the second time for me watching this, just wanted to say THANK YOU!!!
@jessicaparker6626
3 ай бұрын
I was always taught that the cell's overall resting membrane potential is closer to -70 mV. Can you explain why this value is different that the -86 mV that you calculated? Thank you so much! This video was SO helpful!
@ayesharehman4160
2 жыл бұрын
This helps me to understand the topic better.✌
@osmosis
2 жыл бұрын
We're glad our video was able to help, Ayesha! Thanks for letting us know! 🥰
@krupeshprajapati9332
4 жыл бұрын
Unexplainable!!! Unbelievable!!! Thanks🤗🤗🤗
@thecrazygirlxo1347
7 жыл бұрын
very helpful ! thank u
@ahlamalghamdi9303
6 жыл бұрын
wow!!! super clear, feel so good watching this!!
@asdssa2714
4 жыл бұрын
Really amazing ........iam really appreciate your great and fruitful work....thanks🙏
@BTSARMY-sb8sh
2 жыл бұрын
THANK YOU SO MUCH 💜 SO HELPFUL 💜🥺💜💜💜 THANK U 😭💘💜💜
@osmosis
2 жыл бұрын
You're so welcome!
@patiencechepkorir5596
2 жыл бұрын
This is the best video on membrane potential 😉glad to have discovered this channel 🙂😌
@osmosis
2 жыл бұрын
Welcome aboard! Hope you'll also enjoy our other videos! 😊 🙌🏼 🥰
@rikkifrank5681
4 жыл бұрын
I have a way better grasp on this now ty
@eunbii01
4 жыл бұрын
this is the best vid ever
@TraumaticQue9
5 жыл бұрын
Thank you so much, I wish I found this prior to the test. I would have got these answers right. Damn>
@ozzyfromspace
4 жыл бұрын
This was really well done!
@nailaahli4262
7 жыл бұрын
that was useful thankyou please do more physiology videos I'll be grateful for that
@annamarierosicka3845
6 жыл бұрын
Thank you, this was VERY helpful! ^_^ Loved it.
@brendaloaiza790
2 жыл бұрын
wonderful explained thank you!
@osmosis
2 жыл бұрын
You're very welcome, Brenda! 🥰❤️🙏🏼
@user-ul9pv8fu2i
6 жыл бұрын
Thank you this is soo helpful
@Abrar-gi9dn
6 ай бұрын
THANK YOU!
@bsnl230
7 жыл бұрын
Very good explanation, keep posting videos like this :D
@EducatorSharmin
6 жыл бұрын
Its really great understand! Thanks for making awesome video.
@zeenazeena56
Жыл бұрын
Thank you so much, i finally understood this 🥳
@osmosis
Жыл бұрын
Glad it helped! ❤️
@MrTote191
7 жыл бұрын
Could you explain what's the role of the Na K pump in calculating the resting membrane potential?
@dannichols6261
4 жыл бұрын
Yeah, they *don't* explain that at all. They do present some interesting information (ie, ion concentration values). They *mention* the Na K pump, but do *not* explain its role in maintaining membrane potential. Not good! And while they *mention* an 'inward rectifier channel', they don't *explain it* at all!
@magranin7319
2 жыл бұрын
@@dannichols6261 It would be great if they did but I think this video is targeted at people who already have a good understanding of passive and active transport systems. KZitem is great, there are a lot of videos that cover that in depth. I would watch them and go back to this one. Hope this helps :)
@mustafamohamaed9764
Жыл бұрын
very well explained, Great Job ☺☺
@osmosis
Жыл бұрын
Thanks, Mustafa! 😊
@CarrieStandish-n2q
8 ай бұрын
you explain good, and understandable mostly, just all of them number towards the end is a lot and a lil confusing
@spectroxis6418
11 ай бұрын
One thing I’d like to add to this is permeability. At rest without any voltage propagating(action potential) the cell is very permeable to potassium so the summation of these will decrease the effect of calcium, sodium, and chloride a lot and only affect the potassium slightly. GHK equation
@jaemineatschilli
2 жыл бұрын
thank you for this clear explanation!! i have subscribed to your channel and will definitely explore more!!!
@osmosis
2 жыл бұрын
Hi Tengku! Glad you enjoy our video! Hope you'll like our other videos too! ❤️
@jorgemerrengallegos5079
4 жыл бұрын
THANK YOU. Explained it really well mate!
@hg77777
5 жыл бұрын
Great video ! thank you again Osmosis
@_lia7245
5 жыл бұрын
It is the nicest video i've ever watched !! Thank u :*)
@borislavangelov3693
7 жыл бұрын
Great physiology
@wen4768
4 жыл бұрын
Awesome content and i like it so much :DDD
@imperiusss
7 жыл бұрын
wow great! Will you guys eventually also do lectures on neuroanatomy/physiology?
@greenapplejuice23
7 жыл бұрын
we dont fuck with that shit. We are going in on female vag anatomy next!!
@osmosis
7 жыл бұрын
We're mostly focusing on pathology still, for now.
@arieltf2788
7 жыл бұрын
brilliant brilliant video. Thank you A LOT.
@osmosis
7 жыл бұрын
Thank you so much, Arsenic! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZitem? Check it out here: bit.ly/2u35D6J
@fox2splash127
2 жыл бұрын
hi.. can u explain the resting membrane potential during cardiac surgery.. the usage of cardioplegia to stop the heart..
@ninac2696
8 ай бұрын
I UNDERSTAND NOW!
@anujachopda5443
4 жыл бұрын
Great video
@anne-sophiepattijn8302
Жыл бұрын
When calculating the membrane potential for when the membrane is permeable to multiple ions, why is it that when I do the Goldman equation using the information in your video I get -83mV rather than what you got which was -86mV? I did this: Vm = -61.5 x log( ((150 x 0.9) + (10 x 0.01) + (0.001 x 0.01) + (103 x 0.08)) / ((5 x 0.9) + (142 x 0.01) + (5 x 0.01) + (4 x 0.08)) ) = -83mV
@dinaalbushra5364
2 жыл бұрын
Thaankkkk uuuu♥️♥️
@leticiacavalcante2591
7 жыл бұрын
Woow!! Thank you so much for this video!! Awsome explanation
@osmosis
7 жыл бұрын
Thank you, Leticia! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZitem? Check it out here: bit.ly/2u35D6J
@liethsaqer376
2 жыл бұрын
Great work
@osmosis
2 жыл бұрын
Thanks! ❤️
@jethureddy2426
7 жыл бұрын
Excellent!😍 It would really means a lot and nice if you guys upload dailyy one video consecutively!please.......!!!!
@osmosis
7 жыл бұрын
We wish we could! Right now we don't have the funding to do that, but we hope one day we will!
@rajanibuddappagari4682
4 жыл бұрын
Very nice video sir , but generally why potassium is more transferred to out side?
@jacobnutter1639
5 жыл бұрын
I may just pass PT school because of you sir
@andrejmaric5955
7 жыл бұрын
Physiology! Great!
@meharabchoudhury38
7 жыл бұрын
Including the constant field equation would be useful here!
@sunshinetoday7
2 жыл бұрын
excellent, excellent video! I was wondering though, why was the calcium +2 intracellular concentration was not 0.0001? in the video it is listed as 0.001
@jackt6110
4 жыл бұрын
Thanks for the video, good work!
@laurentiu244
7 жыл бұрын
great . thank you
@vadymtrokhymchuk2615
2 жыл бұрын
Inward rectifier K+ channels pump K+ to inside! Not like leak K+ channels that allow to go to outside
@LittleBear2007
4 жыл бұрын
I want to get a really high usmle. Do you have a strategy for that?
@drpoojasau9974
6 жыл бұрын
Very nice
@merajuddinchauhanrajput.6103
4 жыл бұрын
Good
@minggu6908
Жыл бұрын
are the values of each ions here constant?
@nanak3363
7 жыл бұрын
Thank u :)
@hyunjinlee6696
4 ай бұрын
awesome
@masudsiddique8034
7 жыл бұрын
Please upload a video on DIC disseminated intravascular coagulation
@osmosis
7 жыл бұрын
We will eventually! You can vote for upcoming videos by becoming a Patreon subscriber. www.patreon.com/osmosis
@harryshaw5360
5 жыл бұрын
Very useful :)
@rollietocups8592
7 жыл бұрын
curious: is this true across all of life? Same for bacteria, plants, fungi?
@jamasubhankulov5237
4 жыл бұрын
Could anyone explain me from where 61,5 comes in 4:40 ?
@dylanstevens4589
4 жыл бұрын
The first calculation for Potassium is incorrect. It should be -82.8 and not -81.0 as stated in the video.
@maiatwa814
5 жыл бұрын
Why CL is more concentrated outside the cell than inside??? Plz
@layapv6471
5 жыл бұрын
Thank u
@zainabsh629
6 жыл бұрын
is there a vedio for donnan membrane equilibrium
@JackDoodly
2 жыл бұрын
isn' t the nerst forlmula with an ln and not a log? because thats what i am learning
@zo5893
4 жыл бұрын
Thanks for Arabic translation
@raniamalkawi8736
7 жыл бұрын
Thanks , when k+ move to outsid by channel , are the particles of Na+ inter in the same time !? and How it do that , by diffusion!? what is name the process in which particles move from low concentration To highe concentration?!
@alhassankargbo260
2 жыл бұрын
What is the resting membrane potential of excitable cells is close to the equilibrium potential of potassium because. Potassium leak channels makes membrane more permeable to potassium at rest
@ahmadmansour521
4 жыл бұрын
If K+ gets in through electrostatic gradient what Is the benefit of pump then its confusing
@muzammilashraf9426
5 жыл бұрын
want to ask that in guyton the equation has inside/ outside but the equation in video is shows outside/inside. kindly guide me with this thing.
@waledabdelbary4042
5 жыл бұрын
I love this vedio
@martinkasonde4901
4 жыл бұрын
i still don't understand
@dukealecbryansenorin8723
4 жыл бұрын
I do get it but I still cannot get how in guyton did they got the answer -86 millivolts for the exclusive contribution of Sodium and Potassium on RMP in Chapter 5.
@dukealecbryansenorin8723
4 жыл бұрын
By using the Goldman equations and the given values in the book.
@hdtran1001
4 жыл бұрын
well I believe many of you speed up the movie to 1.25 or 1.5x to make it faster to really save time. I did too. As a result, I have to turn it to 1x and play again. Still I dont understand :(
@ishanmewara44
6 жыл бұрын
Na and k only contributes 4% to the concentration gradiant, their main job is to prevent cell swelling.
@dannichols6261
4 жыл бұрын
What exactly do you mean? There isn't just 'one' concentration gradient, they each have their own concentration gradient, as each is present in differing amounts inside and outside the cell. I think you *might* mean that the Na/K *pump* might only function to prevent cell swelling (though I don't think that's true), but I'm not sure what you mean that *their* main job is to prevent cell swelling (that's why I think you are referring to the Na/K pump, not the ions themselves).
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