RHEUMATOID ARTHRITIS SIGNS & SYMPTOMS شرح بالعربي:الروماتويد :الاعراض
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Clinical featuresJoints
The typical presentation is with pain, joint swelling and stiffness affecting the small joints of the hands, feet and wrists in a symmetrical fashion.
Characteristic deformities may develop . they include ulnar deviation of the fingers, ‘swan neck’ deformity, the boutonnière or ‘button hole’ deformity and a Z deformity of the thumb
Popliteal (Baker’s) cysts may occur in patients with knee synovitis,in which synovial fluid communicates with the cyst, but is prevented from returning to the joint by a valve-like mechanism; this is not specific to RA.
Rupture may be induced by knee flexion, leading to calf pain and swellingthat may mimic a deep venous thrombosis (DVT)
Systemic featuresgeneralised
Anorexia, weight loss and fatigue may occur throughout the disease course.
Osteoporosis is a common complication and muscle-wasting may occur as the result of systemic inflammation and reduced activity.
Extra-articular features are most common in patients with long-standing seropositive erosive diseas
Systemic features:Nodules
Rheumatoid nodules occur almost exclusively in RF or ACPA-positivepatients, usually in extensor tendons .
They are frequently asymptomatic, but some may be complicated by ulceration and secondary infection.
Nodules are more common in smokers
Systemic features:Vasculitis
This is uncommon, but may occur in seropositive patients.
The presentation is with systemic symptoms, such as fatigue and fever and nailfold infarcts.
Rarely, cutaneous ulceration, skin necrosis and mesenteric,renal or coronary artery occlusion may occur.
Systemic features:Ocular involvement
The most common symptom is dry eyes (keratoconjunctivitis sicca) dueto secondary Sjögren syndrome.
Scleritis and peripheral ulcerative keratitis are uncommon, but are more serious and potentially sight-threatening complications that usually present with pain and redness.
Негізгі бет Rheumatoid arthritis : Symptoms شرح بالعربي:الروماتويد :الاعراض
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