I was dying to learn this , NOW I'm crying because of your video . T-H-A-N-K Y-O-U
@chloecameron8083
5 жыл бұрын
This has helped me so much to prepare for my exam, thank you!! So clear and simple visuals.
@TedWillingham
8 жыл бұрын
These are some of the best neuroscience videos on youtube. Good speed, through explanation, and EXACTLY the proper amount of depth for someone studying. Many videos are too "overview" or too stuck in the minutiae. Please make one about neuroanatomy of attention!
@cyrenefaithonda360
4 жыл бұрын
Trust me, this is the best explanation available here in youtube, sime. easy. concise.
@anirudhadvaiti475
2 жыл бұрын
One of the best explanation video about basal ganglia I have seen in KZitem till date....simple, clear, concise, descriptive. It especially gives confident for the viewers that they gained some knowledge about basal ganglia without confusions...keep it up✌✌
@i_9704
3 жыл бұрын
Best video I've seen on this. Thank you!!!
@gakyungkim
2 жыл бұрын
Thanks, this is the best explanation I've seen!
@fatimaosama9565
3 жыл бұрын
Thank you so much ...i havn't understand this from any other video ...but thanks to you i have grasp it better now..
@AlexM-pu6kb
4 жыл бұрын
Most concise and most valuable video on KZitem for basal ganglia, thanks!
@mahami2432
8 жыл бұрын
This explanation is tooo good! Thank you soo much!
@nikhilhumane5540
4 жыл бұрын
Best video ever
@MagickSpare
7 жыл бұрын
excellent, learned this very well in 10 mins
@ishansharma4618
3 жыл бұрын
This is like GOD sent me this video 😭. What exactly i was looking for
@plamgogbg
9 жыл бұрын
Another awesome video! Please continue making more
@michaelagarnett8721
8 жыл бұрын
This helped me out so much. So easy to understand. Thankyou!
@eo1964
4 жыл бұрын
perfect video. helped me learn very quickly. thank you!
@dinadoody
3 жыл бұрын
This video is very helpful. Thank you !
@nekkantisravankumar8025
3 жыл бұрын
The explanation simple, easy and awesome. Thank you soo much
@HiuChingLau
5 жыл бұрын
This video is simply awesome. I have looped it for over 10 times every time I need to review the pathophysiology of Parkinson's disease. Thanks!
@safiazaffarullah575
3 жыл бұрын
Thank you so so much! Cannot explain the satisfaction from finally getting the direct and indirect pathways. I watched a couple of other videos, but yours is by far the best explained.
@gautammure
7 жыл бұрын
blooody awesme mate!!!! that was a trademark 007 description! keep it up! i m ur subscriber from now on
@LeTheGenD
6 жыл бұрын
This is gold!! Thank you for uploading this
@angelanvalenzuela4319
3 жыл бұрын
thank you so much!!! this is very well explained!
@hussainahmad6774
5 жыл бұрын
At the end of serching a lot ,I clear my concept from here.Really helpfull ,keep sharing such Vedic.
@aiahsoliman9438
8 жыл бұрын
This is honestly the best explanation I've seen! Thank you :)
@nurulhazimah8941
3 жыл бұрын
Thank you. You SAVED OUR LIVES U DA BEST!
@javierardebolcook5172
4 жыл бұрын
great video!!! amazing explanation.
@themasterkirkfurter3
2 жыл бұрын
thank you so much. this was really helpful!
@whitewolf3115
2 жыл бұрын
Thank you so much for clearing it out ! I found it very useful
@fatimahtahir4727
4 жыл бұрын
Excellently explained
@oksanajames7960
8 жыл бұрын
Thank you so much . This video is so helpful !!
@truptichhajed7709
5 жыл бұрын
I finally understood pathways after a very long time! Thank you Excellent Keep making more !!!
@jasonsinghjohal9984
3 жыл бұрын
Beautifully explained 👍👍
@nehakakde3785
4 жыл бұрын
Thank you soooo much I have seminar tomorrow n this was the best way to learn, and guess what i liked it, as it was v interesting.
@mehradamirnia1680
3 жыл бұрын
Great explanation. Thank you so much 🙏🏼
@asnanoor412
5 жыл бұрын
Nicely explained!! I used it for quick short review .. thanks
@rachel9933
3 жыл бұрын
Thank you so much! Your clear, quick and concise explanation finally helped me realise how the dopaminergic modulation by the SNc was connected to the direct and indirect pathways. This has been a big help
@rafaellalitvin3609
6 жыл бұрын
Very clear explanation and drawings!
@genmasaotome3503
8 жыл бұрын
OMG! I love this... best explanation so far... with pathology of 2 diseases... but how about hemiballismus?
@leddaudet2350
3 жыл бұрын
My Globus Palidus has exploded after watching this video. Good work 👍
@katiemarshall3632
8 жыл бұрын
This is incredible - thanks so much!
@jsp5544
4 жыл бұрын
A big thank you, simply amazing
@zannatul23
5 жыл бұрын
honestly, that was so helpful finally i undertood it, Thank you so much
@notsoanonymous5786
5 жыл бұрын
This. Helps. So. F. Much. I'm shocked. omg I'm still speechless. this helps a lot. Like,, a LOT. No i have a better understanding with direct and indirect pathway, i cant thank you enough for this, but thank you very much🙏
@toobaahmad1954
8 жыл бұрын
smarty summarized n superbly described :) thank you
@mimonabrazily6919
3 жыл бұрын
You made it easier thank you 🌹
@anhaopham3079
2 жыл бұрын
It's such an amazing explanation!!! I saw many video about these pathways before but just this... is the best version I've seen. Thanks you so much
@PV-yl7br
4 жыл бұрын
Thank you so much. It was so helpful.
@YaBoiHakim
7 жыл бұрын
excellent video!
@gargeekanhere3528
7 жыл бұрын
amazing video! highly comprehensive! :) thankyou!
@sarahc.1998
7 жыл бұрын
You finally solved my problem in this part after a long time ago. Really appreciated that!
@udaypratap6133
4 жыл бұрын
Nice and clear. Thank you
@tseyingwah1
5 жыл бұрын
best video ever. thank you.
@くちぱっち-q6u
7 жыл бұрын
Thank you very much! This helped me a lot :)
@leoeostewart
8 жыл бұрын
This is great, best explanation so far. I hope you continue making videos!
@sameepthakuri9550
3 жыл бұрын
When we are considering an indirect pathway without the involvement of DA, the cortex is exciting the Striatum and following on from here we will eventually get to inhibition of the Cortex =withold movement. However, using the D2R in the Striatum, you start by inhibited the Straitum so, shouldn't the final outcome be opposite of excitation of Stratum i.e you end up exciting the cortex = movement initiated for the Indirect direct pathway involving D2R. Can you explain this?
@MrHuddo
8 жыл бұрын
Great video and I hate to bring this up but isn't ganglia a term reserved for grouped nuclei outside of the CNS?
@shubhamsareen4740
5 жыл бұрын
Loved it ...I wasted 2 hrs studying this...learnt in few minutes
@anthonykerbage
5 жыл бұрын
Excellent explanation thank you so much!!!
@chintan2025
5 жыл бұрын
Great work....keep it up...👍👍
@snsh5293
8 жыл бұрын
thank u sooooo muchhh . deserves 10 milloin likes
@ramoncf7
3 жыл бұрын
Fantastic video, but you should fix the volume level throughout the video.
@damnyeahnich
8 жыл бұрын
This is amazing! Thank you so much!
@jiujitsukillah
5 жыл бұрын
Very helpful to learn for USMLE
@jochem7890
4 жыл бұрын
Thank you, this helped a lot! Could you comment on the role of acetylcholine on the basal ganglia? Antipsychotics block dopamine-receptors in the striatum causing parkinsonism. Anticholinergics release these symptoms (at least partially). How do the acetylcholine-neurons integrate in this model?
@PeterDewMedia
4 жыл бұрын
I am prescribed Procyclidine, it is an anticholinergic, a great drug which acts on the acetylcholine system of the brain. I know that acetylcholine is an important neurotransmitter, the effect of this drug is not only alleviation of any side effects but also a really good boost in mood especially if the person taking it were really depressed. It's not used in the NHS or in the world as an anti-depressant but I think it's a really good chemical and would be perfect for cheering people up who were feeling sad, or feeling demotivated. It's not safe to overdose, it's non addictive when taken at safe dosages I have found myself, I take a dose of 10mgs a day and then, even if life can be depressing, I am still reasonably happy. Not all of the anticholinergic drugs boost mood, but Procyclidine seems to do it quickly and very effectively.
@seanneuman523
8 жыл бұрын
This video is amazing. Thanks
@katherinekeough3621
3 жыл бұрын
MY PROFESSOR IS AWFUL AND YOU ARE A GOD THANK YOU FOR THIS
@satoshi3637
6 жыл бұрын
Excellent explanation
@alyaariffin2614
6 жыл бұрын
Thank you so much!
@maximillianhowardpowell232
7 жыл бұрын
quick and simple!
@ilovearizona
8 жыл бұрын
Bless your soul
@kos6681
9 жыл бұрын
Absolutely brilliant! You're awesome!! :D
@vamshikrishnavardhanreddyg3866
2 жыл бұрын
It's Short but yet in depth and made easy for understanding, Thank you:-)
@rickpaulsingh
6 жыл бұрын
Great job. Very succinct in less than 10 minutes. Very useful for my USMLE
@DoctorIsha01
4 жыл бұрын
Awesome! Thanks!
@hellomeme94
8 жыл бұрын
I loved neuromedicine just by watching this video...thank you
@TheekshanaAbayawickrama
3 жыл бұрын
Thank you!
@annabellekaunds3529
4 жыл бұрын
Very well explained; concise yet comprehensive. Thanks a lot
@cygnelearning3605
4 жыл бұрын
this help me a lot. thank you 😭💕
@gentleg.2886
5 жыл бұрын
Brilliant.
@lucastan8127
3 жыл бұрын
Hopefully someone can help me answer some questions! 1) What kind of neurotransmitter is transmitted from the premotor cortex to striatum? 2) How does striatum know to synapse with GPi or GPe? 3) In Parkinson's Disease, why is the indirect pathway favoured?
@nevenanevena6908
5 жыл бұрын
Amazing! Never seen such a good explanation ! Bravo
@SebastianSayed
6 жыл бұрын
This helped alot, thx!
@CH-qg4lp
7 жыл бұрын
Hi do you have any references or places where you got all of your info from?
@PhysiologyOpen
4 жыл бұрын
C H well for all information from standard textbooks.. you need to check out physiologyopen: Basal ganglia physiology | Connections and functions | Direct & Indirect Pathways |Movement disorder kzitem.info/news/bejne/0IePv2xqg4aSnmk
@yeeshao9233
5 жыл бұрын
thank you so much
@MitchellBourisk
4 жыл бұрын
That's spot on! Great supplementary video to my lecture material that I was studying
@georgejones9567
6 жыл бұрын
Surely the GPi cannot inhibit the thalamus as you said? otherwise the inhibition of the thalamus seen in direct and indirect pathways would lead to a different excitatory outcome of the cortex? Surely in the direct pathway, the GPi would excite the thalamus thus causing more excitement of the cortex?
@japooskas
5 жыл бұрын
Think of GPi as constantly inhibiting the thalamus; so no movement. Direct path inhibits GPi, so now thalamus is free to initiate movement.
@kaushikgolagana4544
5 жыл бұрын
You explained the entire physiology n also the two most imp diseases in basal ganglia in a span of 8mins!!! which cud be vry well understood..thanqq soo much Sir!!
@PhysiologyOpen
4 жыл бұрын
kaushik golagana for short crisp videos about everything in physiology, pathology, pharmacology , medicine.. visit physiologyopen Basal ganglia physiology | Connections and functions | Direct & Indirect Pathways |Movement disorder kzitem.info/news/bejne/0IePv2xqg4aSnmk
@themoonlightgirl13
8 жыл бұрын
Really good explanation of the topic, cleared up a lot of confusion on the topic for me!
@MichaelMilord
8 жыл бұрын
You good sir have helped me so much! Thank you for creating this video. Liked and Subscribed!
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