Prithviraj Bose, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the management of early-stage myelofibrosis (MF). He clarifies that early MF should not be confused with pre-fibrotic MF, a distinct disease entity. Early MF is still overt but presents with a less severe phenotype. Dr Bose highlights the role of ruxolitinib, which should be administered early to improve outcomes, as demonstrated by the COMFORT studies (NCT00952289, NCT00934544). This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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