Thank you! This is very helpful! One thing though, around 1:30 or so, you said that whatever is in the lumen gets excreted to the blood, but I think you meant that it gets excreted to the urine. Other than that, makes sense :-)
@Xprince40arab
8 жыл бұрын
greeting and alot of thinks for theses efforts from saudi arabica
@lexismith4944
7 жыл бұрын
Very helpful!! Love watching these videos
@Shubham-iu8nn
5 жыл бұрын
You are the man!! 🙌🙌
@shakee4734
8 жыл бұрын
u helped me a lot sir.. great job
@nourmohamed5938
4 жыл бұрын
Amazing illustration
@lutalobossa9102
9 жыл бұрын
Thanks for the tutorial. Could you please explain how thiazide diuretics cause hyperglycaemia?
@zahraamahmoud5661
5 жыл бұрын
Via the decrease of Cho tolerance lead into increase the level of glucose in blood 😬
@ZoramPavalai
5 жыл бұрын
Because of low K+ levels. There is K+ efflux in Beta cells of pancreas and thus hyperpolarised. So low insulin levels
@ceebladaahir3069
6 жыл бұрын
Best teacher thnk you very much
@briggshightower2609
5 жыл бұрын
Can you explain how thiazide diuretics make you lose potassium?
@esraareda6101
8 жыл бұрын
Greetings from Egypt😊😊😊😊
@wing4382
4 жыл бұрын
Who is the White Woman bro?
@nellyhoffman6194
8 жыл бұрын
thanks Doctor !! :)D
@jaichatha9894
8 жыл бұрын
fukcin awesome. imma pass now
@shubhangijain2972
8 жыл бұрын
isnt early distal tubule impermable to water?? then how does water gets reabsorbed/folows after the sodium here?? and hence how does thiazide cause diuresis???
@mslmsl932
7 жыл бұрын
shubhangi jain by decreasing the reabsorption of Na leading to increase the secreting of water and increase the secret of K due to decrease the const of Na in the tubular so cannot exchange with any one
@doctormwpepper
7 жыл бұрын
Thick ascending loop of henle (site of action of loop diuretics) is impermeable to water, not DCT.
@ned7518
6 жыл бұрын
shubhangi jain you are right. Is impermeable to water therefore it makes urine hypotonic
@madhaviravi359
4 жыл бұрын
Thick ascending loh is impermeable not the dct
@m20superbazooka49
5 жыл бұрын
From India, That is the first line diuretic for non complicated hypertension in here too
@madhaviravi359
4 жыл бұрын
Is the Na Cl channel that acts with Na K pump same as the 1 Na 1K and 2Cl symporter??
@Notundigonto
7 жыл бұрын
thank you so much but whats about the k+ and mg+ change and how after using thaizide
@bijaypaudel9860
7 жыл бұрын
You didn't show the potassium and chlorine channels in basolateral membrane
@s.mshahidullah5351
4 жыл бұрын
E F of my heart is 40.and my heart rate vary from 46 to 58. May l take tab lasix40.
@needserotonin1247
5 жыл бұрын
why it is used in diabetes insipidus??
@sairajabehera6010
6 жыл бұрын
thanke u vrymuch
@nellyhoffman6194
8 жыл бұрын
I have a question if you can answer me :) why does it increase calcium absoportion ????: )!!!
@kamullins
7 жыл бұрын
Because thiazide diuretics upregulate the TRPV5 (not TPVR5) calcium transporter on the basolateral, luminal side, of the epithelial cell in the DCT. More Ca transporters, therefore more calcium reabsorption.
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