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@lithiumferrate6960
Жыл бұрын
Someone should do total synthesis of this starting only with carbon and hydrogen.
@michaelhicks8603
Жыл бұрын
Yea fuggen gday cants. Today were ganna make some Dodecahedrane using the lump of coal Scott Morrison brought into parliament, and some benzine I found in me nans gin cabinet. Shit, this script rights it’s self and it’s fkn gold!!!!!!
@stepulya9108
Жыл бұрын
The old-fashioned synthesis of Pagodane is so fascinating in its simplicity! It is always exciting to see how authors are able to create something outstanding utilizing almost trivial transformations.
@totalsynthesis
Жыл бұрын
Facts. Using symmetry is also powerful!
@Grak70
Жыл бұрын
I can’t find a better word to describe this synthesis than “symphonic”. It combines so many different yet basic reactions in masterful harmony.
@totalsynthesis
Жыл бұрын
Spot on!
@totalsynthesis
Жыл бұрын
Let me know any thoughts on this video and any suggested topics in general - what would you like to see more of? ❓basic chemistry stuff or advanced? ❓natural products, pharmaceuticals, random nice looking molecules or materials? ❓total synthesis, medicinal chemistry or reaction methodologies?
@michaelhicks8603
Жыл бұрын
Hey man, your videos are absolutely amazing!!!! Please upload a video per day where you just read crazy papers like this. Screw the animations, break the stick and balls out. Everyone loves balls ❤ Keep up the good work! 😊
@kshitijkumar5629
Жыл бұрын
I want total synthsis involving organic chemistry!
@totalsynthesis
Жыл бұрын
@@kshitijkumar5629 Next video will be focused on this! But quite advanced
@kshitijkumar5629
Жыл бұрын
@@totalsynthesis hey, can you check that MDMA video comment section, i asked some doubts regarding the reactions.
@totalsynthesis
Жыл бұрын
@@kshitijkumar5629 ive just replied
@atescoshorse8399
Жыл бұрын
Have just covered most of the reactions used in this total synthesis in my uni course right now. Its amazing to see how powerful pericyclic chemistry is and some of its applied uses. Love the videos
@totalsynthesis
Жыл бұрын
Nice! You are right, pericyclics are insanely useful, especially also for tertiary or quaternary centers
@glebanful
Жыл бұрын
Wow, what a brilliant story! Thank you for putting in all the effort, it was totally worth it!
@totalsynthesis
Жыл бұрын
🙏
@lysergicbrew7908
Жыл бұрын
Love your videos, so thankful there is at least a little bit of orgo/synth chem content of this style.
@totalsynthesis
Жыл бұрын
Thanks man!
@joalsoal1645
Жыл бұрын
An odd carbon structure that would be an interesting total synthesis is iceane. It is the building structure for the mineral lonsdalite in the same way that adamantane is for diamond. The mineral is only found in space and has a theoretical moh’s hardness higher than diamond due to its hexagonal diamond lattice compared to the typical cubic diamond lattice. There wasn’t much literature I could find on it however there is a few synthesis papers.
@totalsynthesis
Жыл бұрын
Nice, seems underrated af
@knivesnico8775
Жыл бұрын
This synthesis is so satistying
@spanishSpaniard
Жыл бұрын
I know is "normal" in organic synthesis but ring contractions still fascinate me. The electrons of the carbons in the ring jump!
@totalsynthesis
Жыл бұрын
Oh yeah. Stuff like regioselective migrations as seen in Baeyer-Villiger reactions and others are really nice
@bigjay875
Жыл бұрын
Nice!
@knivesnico8775
Жыл бұрын
Keep griding friend 😤😤😤
@totalsynthesis
Жыл бұрын
💪🔥🔥
@1.4142
Жыл бұрын
Now make super dodecahedrane just like super benzene.
@_juraj_
Жыл бұрын
Can it be somehow nitro-oxydated or manganase oxy-dated to be explosive?
@totalsynthesis
Жыл бұрын
🤣 yeah after closure to pagodane, you might nitrate using the ester groups instead of decarboxylating
@_juraj_
Жыл бұрын
@@totalsynthesis Is it strong explosive?
@totalsynthesis
Жыл бұрын
@@_juraj_ Without nitros not at all, with nitros maybe but probably nothing crazy
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