The team began as Cable's own group of mutant outlaws who fought against f.e. the Externals and Mutant Liberation Front. It later became the X-Men's own secret strike team, a group of mutants who fight for the mutanthood by eliminating external threats.
#20 A big fat mutant that the group has encountered many times while fighting ¤6 and the Brotherhood of Mutants.
#19 A mutant from Weapon Plus Program with skin manipulation who holds grudge against Fantomex and Psylocke.
#18 Ancient Roman politician who became a immortal vampire and henchman of #3, a member of the Purifiers, terrorist group engaged in a holy war against mutant-kind.
#17 Sentinel prime and female version of #9.
#16 Cable's son from an alternate future. He hired Copycat and Deadpool to hunt down Cable and his team.
#15 Anti-mutant terrorist and a member of the Purifiers who turned mutants into living bombs.
#14 An old enemy of the group with plant powers but he later became a member of the X-Force.
#13 The older evil brother of Colossus and Magik who stole Celebro Sword and fights mutants in Krakoa using XENO's "Russian doll" special forces.
#12 Strong being exiled by the Externals, later found and sent by #7 to attack X-Force.
#11 Mutant's version of Dr Moreau, the Leader of XENO who posses Mutant Resurrection Egg to create mutants in Krakoa.
#10 Villain in the Dark Angel Saga when he lured X-Force into his dimension to steal the Life Seed and then betrayed them. Beast later became a dark version of himself after being corrupted in Krakoa.
#9 Super-Sentinel and leader of the Purifiers.
#8 Agent of SHIELD, Cable's former pal from Six Pack who turned on him and started chasing him and his team X-Force.
#7 Powerful External and sworn enemy of X-Men and X-Force.
#6 Angel's dark version, originally henchman of #4 and later his successor when he started becoming the new Apocalypse. Main villain in the Dark Angel Saga.
#5 Tyrant of Mojoworld who is obsessed with making his own broadcasts and enemy of Shatterstar for whom X-Force has had to fight against him.
#4 The most powerful External and leader of his Horsemen to which #6 belongs. He goes against the team in many forms.
#3 One of the most powerful and oldest Externals, succubus-style mutant witch and the team's recurring enemy. She wanted to become a dark goddess through an ancient ritual to drain the souls of re-animated mutants.
#2 Dark clone of Sunspot with powerful fire manipulation, X-Force's recurring foe and the second leader of Mutant Liberation Front.
HM1: He started out as an enemy of X-Force, and later became a member of the team.
HM2: Very strong invulnerable mutant and partner of #14 against the X-Force.
HM3: A Russian arms dealer who has been conducting experiments on mutants, turning them into living weapons.
HM4: A scientist on a secret robotics Project and the creator of his own Synthezoids "High-Breeds" who want to rise and take the World.
HM5: Demonic entity, enemy of Dani Moonstar and Proudstar.
#1 Cable's evil clone created by the Askani and raised by Apocalypse, the founder of Mutant Liberation Front and the creator of the Legacy Virus. He's archenemy of Cable and nemesis of the team X-Force.
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