It's hard talking about psychiatry and psychopharmacology because making broad statements is really difficult considering virtually everyone experiences things differently. I really appreciate Dr. Marks videos, though. I think she does a good job at informing people
@maipai101
Жыл бұрын
You know, living a hard knock life can definitely cause treatment resistant depression.
@jenniferAgbebiyi
Жыл бұрын
Why do I feel like this is actually the number one cause of depression? They say money doesn't buy happiness....well, I beg to differ. I swear if I had more money and was financially free, I'd be 10000 times more happiness and positive about life. But no. Most of us are stuck living pay check to pay check in a world that is seemingly getting worse everyday... and we're expected to be happy??? I sometimes think that the mental health field has it wrong. They say, let's fix the person with therapy and medication to cope with a world that's out of control. I say, FIX THE FUCKIN WORLD.
@maipai101
Жыл бұрын
@@jenniferAgbebiyi I see mental health awareness and self care everywhere. It feels like they are using this to subvert the root of the problem which is economic issues and our lack of time.
@mauriciojr.4428
Жыл бұрын
@@jenniferAgbebiyi Unfortunately doctors don't have that superpower
@kite6864
Жыл бұрын
they hope anti-depressants will make you more content and blind to your current situations. but then you are less likely to try and pull yourself up out of the hole.
@Aladintrip
Жыл бұрын
mushrooms are very rich and help reduces the risk of developing serious health conditions, such as Alzheimer's, heart disease, cancer, and diabetes also reduces anxiety, depression and PTSD. Search the name above ☝️☝️and Send a Dm let's help and guide you through the process 😊😊 You will be glad u did ☺️
@NikkiDoesStufff
Жыл бұрын
I’ve been on lexapro Wellbutrin fluoxetine venlafaxine ..absolutely none of it worked. Then I had a full blood panel done, turns out I had almost no thyroid functionality. I feel worlds better. Sometimes depression is a symptom, not a diagnosis.
@peeweeherman6573
Ай бұрын
Good reminder!
@2buds1shroom
15 күн бұрын
I'll have a KZitem video going up talking about how my Vitamin D (and likely Magnesium deficiency) contributed to my depression. Lived with it on and off for 15 years and it went uncaught (partially because of me)
@charlespentrose7834
Жыл бұрын
I know some people whose depression didn't benefit from treatment, and only got better after they dealt with the thing that was causing the depression. I think more focus needs to be put into determining and helping with such things.
@s7d788
Жыл бұрын
I don't think there's "a thing". I remember feeling depressed as early as 5 or 6 years old. By now it definitely feels like it's something weird with my body and of course life experiences reinforcing negative beliefs make it worse over time
@charlespentrose7834
Жыл бұрын
@@s7d788 Oh yeah, it's often more than one thing, and even if it starts with one thing the way people react to that thing can pile on more hurt. I do hope you manage to get some helpful help.
@paulfairbairn1066
Жыл бұрын
Totally agree Charles.
@pbufh
Жыл бұрын
I suggest you watch a video on situational depression and than clinic depression before making comments.😊
@oneautumnleaf2622
4 ай бұрын
There isnt a thing that is a cure all though sadly, some people really do have depression that nothing can fix or cure, thats why they resort to suicide. because they have no other way out.
@yuyukawa9104
Жыл бұрын
I've been depressed since I was 7 and I don't really know what to do. I have periods of months where I'm not depressed, but it's followed by 8-14months of being miserable, pretending to go through motions of life, anhedonia, suicidal thoughts, misery, etc. I tried everything. Therapy, exercise, medications, meditation, psychedelics, ketamine, etc. I still feel completely and utterly hopeless. Sometimes I wonder if I'm just hard wired to feel constant pain.
@mrhappyforever5133
Жыл бұрын
Go get tested for neurodivergence (ADHD, bipolar, Autism, etc.)
@wilhelmroentgen5373
Жыл бұрын
Did you do psychedelics with a Psychedelic Therapist with proper integration and follow up?
@xxprrrrrrxx
Жыл бұрын
I feel the same way. ❤
@pt87153
Жыл бұрын
You might be Bi-polar. You said you have months where you're not depressed, so your mood might be going up and down. I would tell your doctor.
@strangeduckling
Жыл бұрын
I just did a journal club presentation on "Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression," so this is a super fitting video
@GCT1990
Жыл бұрын
It's just amazing how much psychiatry lies to patients, Maybe Antidepressants aren't working for many because they don't work... Just a thought 🤔 in fact there's no long term evidence beyond 3 months showing effectiveness, safety or improvement on AD meds, why? Because it's well know that Serotonin isn't the cause of Anxiety or depression so.... Why exactly are these people on SSRI/SNRI medications again? Especially when no literature shows safety or effectiveness? And folks... You're basically lab rats, She just said we simply add more AD meds or increase the dosage 😱 what??? You're not treatment resistant these medications simply aren't created to work yet adding more of a substance that doesn't work is a therapeutic option? Make it make sense. The worst is when psychiatrist either gas light you when you experience symptoms by suggesting its your underline anxiety or depression or they bring up the chemical imbalance nonsense that's been not only debunked but abandoned by the medical community in the 80's which here's a thought, if these medications treat the chemical imbalance... Why is mental illness only going up? No one is actually getting better
@brennengodeen3796
Жыл бұрын
I agree with you but if we are being honest, most patients want a quick fix. Look at all these people running to GLP-1 medications for weight loss and are now experiencing horrific side effects. Eat health, exercise, sleep to the best of your ability, eat a balanced diet and then worry about all the meds.
@roxymoran8203
Жыл бұрын
It would be great if you could talk about sleep disorders and how they can be misdiagnosed as different mental health conditions in a future video! I've been thinking about getting tested at a sleep clinic for a sleeping disorder since I've been dealing with treatment-resistant mental health issues for a long time and the symptoms can overlap.
@KathBorup
Жыл бұрын
Yes. I have bipolar disorder and one of my worst symptoms was insomnia. Took a long time to get correctly diagnosed. Not saying that's the issue in your case, but I agree it's an interesting video idea!
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from
@joysamuel6318
Жыл бұрын
Dear With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@steelstrings87
Жыл бұрын
I have a family member who works in this field and has mentioned that sleep apnea can also cause anxiety and depression. Could be worth a sleep test. (You can do them from home in a lot of cases now--you go into the sleep center to get a kit, take it home and the data goes to your Dr.)
@s1south
Жыл бұрын
Its important to remember that some people with fibromyalgia and resistant depression are actually neurodivergent but havent been diagnosed/discovered. Specially women.
@bunyip250
Жыл бұрын
Look up EONutrition and high dose B1. It's given me some relief.
@mrhappyforever5133
Жыл бұрын
THIS. So much this. Thank you. I’m so tired of mental health providers being lazy and slapping “chronically depressed” on a lot of struggling patients. If the treatment isn’t working then something is being missed! Maybe like… geeeee I dunno….. NEURODIVERGENCE!
@DeltaNovum
Жыл бұрын
I also believe that pain and weird symptoms that come and go can be trauma manifesting in the body. Some people that I know experience many of the same things I do (pretty sure it's my many many and longterm trauma's) and they call it fibromyalgia. I wonder if fibro is the same thing?
@user-xy4ff5yp7b
Жыл бұрын
Sources please?
@spacecat8511
Жыл бұрын
(to the op) YEP. I cannot take serotonin medications at all. That’s literally all antidepresants and lyrica for fibromyalgia (that I’m not even sure I actually have, as I’ve since been diagnosed with ankyloising spondilitis, hypermobility/connective tissue disorder, and chronic fatigue, but fibro’s still on my chart. Whatever.) Like. Trying to take serotonin *increases* my anxiety and depressive and chronic pain symptoms to being the WORST I have EVER felt with my emotions and thoughts spiraling uncontrolably to the point I was scared I’d actually hurt myself or do something negatively impulsive. WHICH got me bullied by one old psychologist, accused of being “resistant” by another former therapist, and yelled at by a psychiatrist I tried working with through CMH. The fact that I suspected (and was later diagnosed with) ADHD didn’t seem to factor in At All. That low dopamine and trauma can cause anxiety/depressive symptoms just as much as not enough serotonin. Aaaand my serotonin sensitivity? UH. Probably serotonin syndrome which yeah it can kill you…and my best guess? My serotonin is FINE since I Do Not score high enough on the handbook screening for bipolar to bother seeking out a formal diagnosis-but again, there is existing adhd which is, y’know, issues with dopamine. And Low Dopamine and Low Serotonin can look similar!!
@obgfoster
Жыл бұрын
Switching from Prozac to Effexor to Pristiq (all generic) and then adding Buspirone helped me get over suicidality, but then it turned out a lot of my supposed depression & stress symptoms were due to ADHD. I'm a different person now that I'm also taking Concerta. My resting heart rate actually went down after starting on a "stimulant!" Also, I never lose my phone anymore.
@obgfoster
Жыл бұрын
(and I had a vitamin D deficiency, which made things worse).
@brntmoondoll4jaw
Жыл бұрын
Concerta is a godsend omg I've been taking it for like 3 years now. Adderall and Vyvanse were too intense and caused too many mood fluctuations. Concerta is like the perfect balance for me
@KiwikimNZ
Жыл бұрын
I was one of those who did not get my adhd diagnosed till I was 50! I’d been diagnosed with bipolar which was not the case and been on too many antidepressants and antipsychotics to mention.
@brntmoondoll4jaw
Жыл бұрын
I really, _really_ hope that people don't leave this video and take away that "Lamictal makes depression worse". It COULD make depression worse IN SOME PEOPLE....when you compare that to the MILLIONS of people who take it successfully, it's really low-risk
@oneautumnleaf2622
4 ай бұрын
Yeah its def worth trying, sadly for me it made my depression way worse and the withdrawal was miserable, but I still gave it a shot.
@stephdalek4273
Жыл бұрын
Interesting. Lamotrigine has actually helped my depression a lot but the SNRI I tried was unbearable.
@BlackMarilynMonroe33
Жыл бұрын
My Mom and I both take Metoprolol for HBP, and I recently started Lamotrigine for Bipolar 2-I’m shocked that the latter can cause depression when it’s prescribed to treat it. Also, no surprise that hormones play a part in depression. It’s hard to feel good when hormonal imbalance wreaks havoc on your mental and physical health.
@brntmoondoll4jaw
Жыл бұрын
A lot of medications designed to treat depression can make it worse. That's just the way it is right now. For example, a ton of people get relief from Wellbutrin, which takes about a month for full effect. But for me, it's the exact opposite, I gradually get more depressed and after a month I realize I'm more depressed than I was when I started Wellbutrin. It's just how it is. I really do feel for you in regards to hormonal impact on depression. I often tell my mom I don't think I'd make it if I were born female bc of the (potential for) drastically fluctuating hormones
@BlackMarilynMonroe33
Жыл бұрын
@@brntmoondoll4jaw thank you for your empathy and understanding-it seems I can only count on understanding from others going through similar mental health experiences. Starting new meds is such a disheartening experience. The titration schedule is slow and painful with no guarantee that it’s going to work for you. With so many classes of meds to choose from, finding the right meds can take forever. And, treating menopause can be just as difficult. I wouldn’t wish what I’ve been through on my worst enemy.
@NatureHeadSupreme
Жыл бұрын
I too once did the Lamotrigine dance along with a bunch of others. I stopped all medication once I started processing trauma. A lot of the mental disorders are really TRAUMA - and im not saying trauma is any better or worse than "bipolar" but medication isn't going to cure trauma. The only way out is to face it, it hurts too. Exposure/response & platonic touch therapy are incredible for trauma. Best wishes. 🌎
@wiii432
Жыл бұрын
Elimination diet's work & exercise to boost results / Yoga.
@monogramadikt5971
Жыл бұрын
prescribing medications for mental illness, sounds like a game of pin the tail on the donkey
@kwkw5711
Жыл бұрын
Amen brother.
@codexamalgam5939
Жыл бұрын
I strongly support the use of medication because it saved my life but even I agree, it took 3 SSRIs to get it right and that's not counting the stuff I tried for anxiety, tremor and migraine (none of which I bother treating any more)
@NemanjaTalic
Жыл бұрын
I have started combining magnesium citrate and Omega 3 supplements and finally have anxiety-free sleep.
@dynamogaming4953
Ай бұрын
Can you share more your reply means a lo to me 😊
@mwwhatever
Жыл бұрын
On my 8th ketamine treatment and still no improvement. I'm sick of trying
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@chadrickshillings4
Жыл бұрын
I'm on lurasidone, propanalol, colonodine,zolpidem, and prosasine. Bipolar with sleep deprivation. I always try to watch the new videos. I was just taken off Duloxotene because of nightmares but, they linger some still. I'm slipping back into the Listless feelings again. I actually talk to one doctor tomorrow. Hope I can convey my thoughts clearly.
@Vates104
Жыл бұрын
Thank you, Dr Marks. I have learned a lot from you.
@wilhelmroentgen5373
Жыл бұрын
Was on ssris and snris but they didn't work until I did psilocybin with a therapist and my life has never been better....and that was almost a full year ago. I also take magnesium and probiotics everyday.
@danakennedy5072
Жыл бұрын
I have been on Cymbalta for many years now, 60 mg. So many times I've tried to get off it... tapered the correct way. Last time i made several months, but the level of anger i had was frightening. I guess i will be on it until i die.
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from
@joysamuel6318
Жыл бұрын
Dearly, With the help of Dwayne_myco, a mycologist who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@BeautifullyReckles
Жыл бұрын
Undiagnosed neurodivergence. Especially in women and poc.
@saralangley6691
11 ай бұрын
Been on all but one antidepressant since I was 13. Did 14 years of therapy, DBT, exercise, etc etc. I’m still fucking depressed. Nothing helps.
@diegogonzalez9020
Жыл бұрын
After 20+ antidepressant trials (including an MAOI)I was ready to give up. It wasn’t until the maoi induced hypomania did I realize my depression may be more than just unipolar depression. Currently only taking two mood stabilizers and feel better than I have in years.
@morio9284
Жыл бұрын
That means you have bipolar 2 (manic depression)? And antidepressants do not help you, but only mood stabilizers help you against depression and hypomania? I have also bipolar 2, i take currently Mirtazapin 30mg against depression and my very bad sleeping disorder, but it doesn't help very well, but at least i can sleep a little better. So, as you say mood stabilizers could also help me much better, as you experienced it? Kind regards,
@diegogonzalez9020
Жыл бұрын
@@morio9284 my doctor thinks that it’s likely I have bipolar 2 as no antidepressant really helped me at all. I was on mirtazapine at one point as well. It did nothing for my depression or anxiety, but it did help me sleep. Medications are different for everyone, and it takes a ton of trial and error (at least for me it did). I would bring this up to your doctor to see if it’s the right step for you. Mood stabilizers have been the only medications that really helped me out of all of them.
@GeraltOfRivia99
Жыл бұрын
Did you have mania? like periods where you would be energized and couldnt sleep and motivation? than i would say your bi polar. but for myself im in the same boat as you i have MDD and GAD and ive tried over 12 meds man and none have worked......so im in hell. i dont get any manic phases tho at all
@owenmacleod8681
10 ай бұрын
lol same except I ended up with type one instead. So much for my trd my whole world has been turned upside down
@OfficialRogue
Жыл бұрын
Hi Dr. Marks, thank you for your very educative and helpful videos. I was wondering, can depression within bipolar disorder also be considered treatment resistant when it's not responding to 2+ treatments (including the mood stabilizer)? Suffering from bipolar type 1, Ive only had ONE real manic episode with no real/big consequences about 8 years ago (i was 19). Other than that my illness has mostly manifested as depression and very rare euphoric moments (mostly internal feeling and lasting less than 4 days, often just for a day or night when i suddenly got the motivation e.g. to do some one-time major cleaning). Meaning I guess that it feels like I have bipolar type 2 outside of that one manic episode very long ago, that doesn't feel like it would happen again to be honest, I would also react and recognize it very fast if it were to manifest again I think... I've then had my first hypomanic episode (lasting between 2 weeks & a month) last December which allowed me to have motivation & job-hunt, and find work again as part of my masters (work-study apprenticeship).. but after 2-3 months i crashed again into a hard depression and have been on extended sick leave since then ... I was on Quetiapine and my pdoc added Sertraline since march (now at 150mg) and it hasn't helped that much either...no side effects from the sertraline though, feels like it has no effects, and idk if i can attribute the "better" days i've had of feeling better to it or just regular mood changes.. I feel very defeated and powerless despite trying so hard to get better.. and i've got deadlines and constraints, meaning i can't afford to remain like this indefinitely... Another question: After hearing about ketamine and psylocibin and other promising treatments for depression, I've asked my psychiatrist about them, and she said "those are not for you", meaning they're mostly for unipolar depression (and also that we haven't tried all the other options to get there in the first place)... Sorry for the very long comment and thanks again for your videos, I've learned a lot and find educating myself on these topics helpful. 🤍🙏
@stevenkovler5133
Жыл бұрын
My resistance is due to the fact that my anxiety and depression come from being $70k in debt! Medicine can not cure that .. only finding 70k can ..
@chilenapromedioRU
Жыл бұрын
Thank you Dr. Tracey. I have treatment resistant major depression but doctors doesn't seem to care, because they know they will not see me for a whole year, this is how unfortunately the system works in my country. I've been for at least 4 years with venlafaxine 300 mg/day and it made life bearable, from all the dozens of anti-depressants I've tried, I think it's the one that works the best. I take sublingual clonazepam SOS for GAD and panic attacks. That's all the doctor give me (they don't even put me a proper psychiatrist, it's a family doctor who works for this mental health program in my country, nothing I can do about it). All my tests results were impressible good, even vitamin b complex and vitamin D, as someone who doesn't go out and has to wear tons of sunscreen and is a vegetarian going vegan who doesn't take supplements, I was very surprised, I don't even have anisocitosis nor anisochromy (sp) anymore. I do take birth control pills because of retroverted uterus and endometriosis and topiramate, but topiramate it's wonderful preventing migraines, so I really don't think it's bad, actually it's worst if I don't have it. The doctor told me to take all my meds. But I don't have hope in a solution. I did DBT and it did help me with my PTSD but it doesn't "cure" you, it only give you some new tools. And ketamine? That's only for veterinary use in my country! I don't know if they use it in human hospitals. It's a very controlled substance because there was a time kids abused it, we are way, way behind first world countries. I just wait patiently for my day to depart to come. As patiently as I can. I try to put my best face to my close relatives, fortunately they're few. But it's getting really tiresome to wait for that day 20 years and still waiting...
@tonyivan508
9 ай бұрын
I really hope you get a better life my friend, but what country are you from?
@xxprrrrrrxx
Жыл бұрын
I'm taking 400mg of Lamotrigine, Desvenlafaxine, hydroxyzine, clorazepate, and five other medications. None of them are helping me with my major depression, suic***l thoughts. Aggressive bipolar/happy/hyper/crying for no damn reason mood swings. I don't sleep for days at a time because I also have insomnia, and I have ADHD, major PTSD (apparently). I can hardly eat, I avoid people because of my rapidly aggressive behavior, and It sucks!!!!! Sorry for my venting, but a lot of times I feel like the medications are nothing but a placebo.
@mameeocean6194
Жыл бұрын
I just started Spravato therapy.. my momma passed away after my 4th session so I’m in a setback, but I started to feel a difference.
@codexamalgam5939
Жыл бұрын
Sorry for your loss but I'm so glad it's working for you ❤
@sgr_sgr
Жыл бұрын
Tracey, I’d just like to say thank you for the time & effort you put into making these videos! In essence, from my perspective, your channel represents one of the most valuable core benefits of the Internet - a place to learn. I’m so grateful to you for the way you’ve helped to demystify the subject of mental health. Here in England the statutory (government funded) mental healthcare system lies in tatters The dangerously underfunded mental healthcare support system is dwarfed by the demand, causing further trauma to the patient. Please could you make a video attempting to quantify the impact on a society in which people who are in need of mental healthcare are faced with a statutory funded mental healthcare system which is, itself, operating in a state of crisis.
@TWICException
Жыл бұрын
After 5 years of trying so many different medications and therapy, it turns out my treatment resistant depression is easily treated by ADHD stimulants for my lifelong undiagnosed ADHD.
@charlespentrose7834
Жыл бұрын
I'm glad you were able to get helpful help, even if it was late. Like you getting treatment for my ADHD made a big dent in my depression.
@antoine-olivierdeshaies-le2307
Жыл бұрын
@DrTraceyMarks Can you make a video on the cognitive biotype defined by the new Stanford study on depression.
@addysaw
Жыл бұрын
1. Not me using Lamotrigine in the past to treat my depression, and now finding out it causes depression 2. I dunno but Ibuprofen sometimes had a lifting-mood effect
@breakingpoint3893
Жыл бұрын
That's interesting that you say that about lamictal. I was on it a couple of times, and it made me feel worse, never better, and doctors would coax me into staying on it even after they were told about how I felt. Also, ibuprofen can help with mood because it's an OTC anti-inflammatory. infused to help me out too, but I can't take it because I'm on lithium... I hope you're doing better!
@addysaw
Жыл бұрын
@@breakingpoint3893 i had the exact experience! I communicated feeling worse, so they increased the dosage. I followed their orders and, you guessed it, I felt much worse. Eventually I lost trust and got off it.
@retro51fan
Жыл бұрын
Alcohol abuse leads to down-regulation of D2 receptors; in many (most?) cases, this down-regulation reverses after the alcohol abuse is stopped. In my case it didn't. I've been taking Wellbutrin for many years and it stopped working for my depression after I became sober. My specialist increased the dose to the maximum (450mg/day) but it's doing nothing for me now. I tried all the other anti-depressant classes before I started on Wellbutrin and they did nothing for me-- Wellbutrin worked...until it didn't. My specialist and I agree that I should try something completely different like ketamine or deep transcranial magnetic stimulation. Wish me luck! Thanks for this video, Dr. Tracey!
@brennengodeen3796
Жыл бұрын
You should ask them about the new BUP that has DXM (dextro.). It has a the same MoA as Wellbutrin affecting the Dopamine and Norepinephrine but also has a very unique MoA as the DXM targets NMDA receptors and produces an entirely different effect. Think of it as a much weaker ketamine.
@retro51fan
Жыл бұрын
@@brennengodeen3796 Thanks so much---I truly appreciate this! I took a screenshot of the info you shared and will show it to the psychiatrist (have a referral, waiting for appointment). With appreciation from Canada 🙏
@GeraltOfRivia99
8 ай бұрын
@@retro51fan it's been 5 months since your last comment t did anything help or anything your trying new?
@retro51fan
8 ай бұрын
@@GeraltOfRivia99 That's very thoughtful of you to ask! I saw a psychiatrist this month and she's going to get my family doctor to prescribe Abilify for me, to be taken along with my Wellbutrin. I'll leave a follow-up comment here after I've tried the combination for a few weeks. I really appreciate you help/advice--many thanks again!
@ashman4357
Жыл бұрын
I took sertralin and it made my head go numb and my tinnitus became unbearable
@codexamalgam5939
Жыл бұрын
I had the same side effects as well as complete appatite loss
@noonoovrrr
Жыл бұрын
Thanks for sharing your expertise in an understandable manner without oversimplifying the topics ✨🔬 I have a question about treatment resistance in general. I tried taking many types of psych meds across all major classes. No matter what drugs I take, I need much higher doses to have a proper (or any) effect. At the same time, I never had any side effects. I’m on 200% of the maximum dose of Elvanse, the maximum dose of lamotrigine, and the maximum maintenance dose of quetiapine. It works fine in my daily life, but I don’t have any room to increase the amount in case something happens, or my tolerance develops over the years. Is there any explanation for people being more or less sensitive to all psychotropic medications? P.S. I'm diagnosed with bipolar, autism, and ADHD, and I have no somatic conditions.
@ryanquinn527
Жыл бұрын
Dr Marks can you explain C-PTSD in detail?
@Hi_Im_Akward
Жыл бұрын
I didnt know medication resistance was so high... This video explains a lot in retrospect. I'm medication resistant to all but one antidepressant and that one caused chronic migraines. Worst part was it took 2nd and 3rd opinions from psychiatrists for one to finally believe me that the meds made my depression worse. She was great, explained the process and we went through each type of antidepressant in a systematic manner. Finally ended up on meds meant to help with energy levels for people with MS and was mainly treating my depression with therapy. Several years later, I now have a fibromyalga diagnosis. Im on a low dose symbalta to treat it and my quality of life has significantly improved. I also recently got diagnosed with Autism and ADHD and treating those with ways to accomidate and cope with life... significantly different perspective on life and significant improvement in depression symptoms because I'm not forcing myself into a box I don't fit into... sometimes depression is a symptom of bigger issues rather than the actual illness.
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from.
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@Dulcimerist
Жыл бұрын
SSRIs made things a lot worse for me. Impulse control and compulsive shopping resulted from those. Cabergoline helped me the most, since hormone imbalance (high prolactin) was a major factor. Amantadine has helped a bit as well, since it boosts dopamine and reduces fatigue. Guanfacine/Clonidine got rid of my anxiety, migraines, and insomnia. They directly calm the "fight or flight" response to reduce anxiety, even though technically they're ADHD and blood pressure meds.
@Cathy-xi8cb
Жыл бұрын
This is excellent! So many people have no idea that their meds for other diagnoses could be CONTRIBUTING to their depression. The prescribers often don't know either. For every mental health provider that is not a healthcare provider, you have been schooled, my friend! Time to educate yourself.
@DrTraceyMarks
Жыл бұрын
That’s right. Education/information is power. 👍🏽
@clementm9161
Жыл бұрын
I am worried. I've been depressed for over 10 years. I used to be passively suicidal, for a few days here and there. But nowadays I have suicidal thoughts pretty much every single day. I can't get anything done during the day. I barely eat and do the minimum to survive. I have a low wage job that I hate, where I struggle to do the easiest tasks. I have no one to talk to. This life makes no sense and I am suffering. The pain is mental as well as physical. I am slow and tired after just a few hours into the day. I've been on the verge of killing myself 4 years ago. But I've decided to withdraw inside and completely gave up on life back then. Wasted 3 years of my twentie, at home. I feel like doing the same very soon. Isolate and just wait until I pass away.
@joysamuel6318
Жыл бұрын
Have tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from. I recommend this great mycologist to you who really helped me out, on depression and anxiety
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@rachelfarmer0277
Жыл бұрын
I'm definitely medication resistant.
@oneautumnleaf2622
4 ай бұрын
Ive been through 10 medications, and also did a DNA test and it showed every anti-depressant wouldn't work, we tried some anyways and only 2 said they would work and they made me miserable, the first didnt work and made my depression worse, the second gave me a Serotonin overload and caused me to be stuck in bed for almost 2 months vomiting and unable to hold down food, shaking, cold chills, and barely able to even use the restroom. Ive tried pretty much everything. Tried weed, it helped a good amount for a year, then I started to develop Psychosis so weed is now out of the picutre..... my last option is shrooms but its illegal in my state lol. I hate it here.
@nothing563019
Жыл бұрын
This channel is gold. Thanks so much for your help Doctor.
@DivineGuidanceTarot
Жыл бұрын
I’m taking hormone blockers for breast cancer. I also take medication for hypothyroidism. I’m taking Lamictal for bipolar 1. I still get frequent depressive episodes. I also suffer from anxiety attacks. I’m at a loss now because I don’t know what to take to alleviate my symptoms. 😢
@iseewhatyoudidthere1245
Жыл бұрын
Excellent commercial for Big Pharma!
@loriallen67
Жыл бұрын
Thank you for this video. I learned I have more physical reasons than I thought I had. Appreciate the useful info.
@LisaLee__
Жыл бұрын
How long did they stay in remission? I had depression from 11 to 22. From 18 to 23 I had a huge boost from being addicted to opiates (vicodin & percs). After rehab, I found Jesus and had remission. Except I truly believed I was cured. It was like waking up. I couldn't even recognize my own memories as my own because I changed so much. But many life changes all at once hit 2 years ago, plus being chronic illness such as 20 + migraines monthly finally took me out. I've been in this terrible depression for two + years and what I learned was that depression isn't curable. This is a staggering realization. It's something that I will deal with forever until I die. I look forward to remission but it may never come. Point I'd, more people should be aware that depression- from chemical imbalance or genes or clinical depressive disorder is something you will struggle with your entire life. I really wish I would have known. Maybe I could have prepared. Idk. I don't wish this on my worst enemy. There must be a cure. A way to rewire the brain. Something accessible. Sorry for the long and detailed secrets in this post.
@obgfoster
Жыл бұрын
Depression is not incurable for most, and even if it is, it's treatable. Have you had an MRI? with both migraines and depression, could there be something else going on?
@LisaLee__
Жыл бұрын
@obgfoster appreciate you taking the time out. It's so kind of you. Truly I've had chronic migraines since I was 9 years old. I have had MRIs but never for both depression & migraines. It does make sense if they are related.
@Heather28400
Жыл бұрын
I’d love your thoughts on the new research from Stanford Medical about the cognitive biotype of depression
@jgrant2k
8 ай бұрын
Hello Doctor... I wanted to let you know that after watching this on Christmas Eve last month, I immediately stopped taking Singulair. I was so severely depressed that I left my sister's house on Christmas Eve. I got home and I had enough, and I started researching a way to fix this. It's been just over 2 weeks now and I have noticed a drastic change in my severe depression issues that I've been suffering from for over 25 years. I was taking Singulair since it's release in 1998, and I even had to get authorization from my insurance just to get it. I had no idea there was a box warning from the FDA and none of my doctors ever said a word. Thank you for bringing this to my attention. You have helped me more than you could possibly imagine.
@Kingboo1081
Жыл бұрын
Treatment resistant mdd, gad and agoraphobia of 9 years. 30 + med trials. ECT. Psychotherapy. Just getting worse.
@karenswartz8280
Жыл бұрын
This was very informative. Although I wouldn’t go so far as to say I had treatment resistant depression, I definitely had difficulty regulating it, as I have bipolar disorder, depressed. The depression was the greater issue. I was fairly well controlled on Effexor SR, and Lamotrigine for many years, but in the last 2-3 years, nothing seemed to improve my latest bout with depression. My psychiatrist talked about a medication change in my antidepressant, as perhaps being on it so long caused it to no longer be effective for me. So, we tapered off Effexor in preparation for the change, leaving only the Lamotrigine. And much to our surprise, I improved greatly without the ant-depressant and only taking the mood stabilizer. I’m not saying that would work for everyone, but, thankfully, it worked for me. Ironically, (or not), I do take 3 of the medications listed!
@JSFGuy
Жыл бұрын
😏.... Having a security clearance prevents diagnosis and treatment.
@alalbavincerovincero
Жыл бұрын
I amautistic, have adhd, pcos and pmdd. Yay. Prozac didn't work with my anger until i started taking anti androgens. I take 3 of them + brzilian nuts for my hypothyroidism. I'm feeling less miserable, not angry anymore and awake.
@pt87153
Жыл бұрын
I would be really careful with zolpidem. I was put on that med by my PCP during the pandemic to help with sleep, but it ended up making my depression/sleep worse. I'm still battling mental health issues caused by the pandemic and that drug.
@brennengodeen3796
Жыл бұрын
I’d stay far away from any long term use of GABAergic medications.
@artheemisia
Жыл бұрын
A strict low carb diet + no wheat and dairy helped me a lot
@tracyzimmerman7912
Жыл бұрын
I have MS. This also has an affect depression.
@Cathy-xi8cb
Жыл бұрын
There are research studies out on the risks of depression from the drugs used to treat MS. All you have to do it search for it. Making certain that you have the lowest effective dose of your MS drugs is essential, as is not staying on the drugs if they don't work for your target symptoms. You may have to be a strong advocate here. All the docs are hesitant to switch things up. Press them based on this information you now have.
@rozerenity
Жыл бұрын
Hi dr. Tracey can you pls talk about Toxic Shame in one of your videos? Thank you
@echase416
8 ай бұрын
My fmr husband was a psychiatrist for 25+ years. For patients w/ Tx resistant depression, one strategy was trying a medication, such as Dexedrine or Ritalin.
@WwZa7
Жыл бұрын
Oh my god, if someone told me that a surgery has 67% success rate, I wouldn't risk it...
@brennengodeen3796
Жыл бұрын
Nor would I expect it to work. I feel my best when I’m hard on myself and stayed disciplined. Feeling sorry for yourself gets old.
@staytuned2L337
Жыл бұрын
It takes a lot for me to watch your videos. I know there's a lot of things that I need help with, and with topics like this especially it hits home way more than I'm comfortable with.
@maxdaisy84
Жыл бұрын
Thank you for the Arabic translation. It means a lot to me. I want to educate myself more about mental health, as I have struggled with anxiety disorders. Thank you very much for your efforts to convey information🙏🤍🤍🤍🤍
@DrTraceyMarks
Жыл бұрын
I’m so glad to hear from someone who’s using the translations. I’ll be sure to keep including them 😊
@junimondify
Жыл бұрын
I have tried most of the SSRIs and SSNRIs + Lithium and it just is not working. Thankfully, I got my next apointment with my psychiatrist next week, but I am losing hope.
@napoleonfeanor
11 ай бұрын
I think the biggest reason for my treatment resistant depression are social factors like my lack of social skills making me a loner and not seeing a future for myself as I am chronically ill and also have ADHD (inattentive type) so I am often either motivationless, cannot properly plan things due to procrastination. That has made my university studies harder. Once I start something, I will finish it but starting is really hard. Bupropion helps me a bit but not enough. Had maaany different antidepressants already and all of them for many months and in high doses within the range.
@owenmacleod8681
10 ай бұрын
How old are you if you don’t mind me asking? If you’re in late teens be on the lookout for bipolar it smacked me in the face after almost four straight years of awful depression and inattentiveness
@Miss_Millie_
Жыл бұрын
I've been on 2nd daily ketamine (450mg) for 5 yrs. Initially it helped but my tolerance grew with time & now I'm experiencing bladder issues & "ketamine cramps" - severe pain that leaves you feeling like you're dying - I vomit the pain is so bad. I've tried about 20 pills & I'm so very tired of being on meds, suffering side effects & not getting any relief. I don't think ketamine troches work as well as IV & I think it should only be used as short term therapy with a plan to taper. I think my current mode of therapy has left me worse off but my psychiatrist doesn't want to change meds. I feel so lost - I can't keep living like this!
@cannibalcatgirl
Жыл бұрын
Have you looked into the study about SSRIs and autism? The timeframe of the increase in autistic kids being born and SSRIs popularity is wild. They also did a study where they gave pregnant rats SSRIs and their offspring also exhibited similar antisocial and “odd” behaviors similar to what an autistic human would. I’d love to hear more professionals look into/ discuss this.
@HillbillyYEEHAA
Жыл бұрын
They've never been tested in pregnancy
@walexander8378
Жыл бұрын
Very important to get in touch with your inner self. Focus on everything going on in your body. Pains, nerves, breathing, emotions, stress signals, fatigue. Ive learned to do this over the course of a few years and Ive gone from being an agoraphobicwith s thoughts to now working almost full time and considering traveling overseas. Ive lost 50+ pounds at one point and then was able to add a lot of muscle. Im able to focus on things I need to a lot of the time. Ive learned to bake bread and I tend to a vegetable garden. I have a long term girlfriend...etc. All because I learned to have self discipline and control my thoughts and actions for the most part. I thought I had treatment resistent depression but really I had no self discipline. I went through way more than 3 medications with no effect, was in weekly therapy for almost 4 years until I started disciplining myself. My therapist was funny though, the final year or so I was able to see him and after 4 years with me, he was in awe of what I was doing as I continued to tell him Im off all medocations. He kept an eye on me the last year and let me do my thing and I think I surprised him quite a bit. He saw me struggle even on medication to being on no meds and starting to thrive. So it is possible even if you think theres no hope. Just find a self discipline that works for you. Listen to your body
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@DonnyNoMarie
Жыл бұрын
I don't know if this qualifies as "treatment resistant," but if you are experiencing unrelenting stressors, swallowing antidepressants isn't going to help.
@mirceapauca8541
Жыл бұрын
Antibiotics in the "flox" / floroquinolone family (ciprofloxacine, levofloxacine) may cause agitated or confused depression along many other somatic side effects like sun/UV hypersensitivity, muscle or tendon weakening up to rupture...
@littlemissnobody9657
Жыл бұрын
Help! Can I talk about type 2 bipolar and what will happen if we are forced off of meds for insurance reasons what should we do
@WillfullyWondering
Жыл бұрын
What about any psych meds? My body doesn't like to let medication stay in my system long. Abilify being one of those...
@obgfoster
Жыл бұрын
That Genesight test is supposed to identify the best drug. It's expensive, though.
@WillfullyWondering
Жыл бұрын
@@obgfoster Noticed. Medicaid won't cover it here.
@roadlesstraveled34
Жыл бұрын
I'm too afraid to get treatment; how could you treat grief that's no better after two years? I cry constantly and seclude myself and my 4yo. Only one person knows how I really feel: that I resent my kids because they are the reason i can't be dead like my fiance. If I tell someone what I feel and believe there's NO WAY I'd be walking out of there. I don't like antidepressants; I take Xanax, Valium, Ativan, or Klonopin. I was prescribed Ativan, then my doctor abruptly retired. So I had to take matters into my own hands; I know that you cannot abruptly stop taking benzos.
@joysamuel6318
Жыл бұрын
Have you tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from.
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@rileykittendorf
Жыл бұрын
Hi Dr. Marks. I have so much I’d like to discuss, but if I’m on antidepressants and mood stabilizers for bipolar disorder, but need an antipsychotic for schizophrenia, isn’t that a counterproductive solution? I think the antidepressant and antipsychotic are trying to both affect the dopamine and it cancels each other out. My psychiatrist does NOT want to take me off Effexor or lamictal. I must’ve taken over 15 different medications and combinations. It’s all failing. I have fibromyalgia as well. Thoughts on the antidepressant with antipsychotic?
@dmgsoultogetherness6667
Жыл бұрын
i was on the brink of ect...thank god i changed my mind iv lost count of the meds iv been on....the change overs made me worse
@donnawiseman3686
Жыл бұрын
Just asking is it true your meds wont work if you are drinking or taking drugs? I have had fibromyalgia and chronic fatigue around 30 years and add menopause ans stressful family situations and i battle anxiety and deppresion
@addysaw
Жыл бұрын
Honestly a ton of people I know drink and do drugs whilst also taking meds and it doesn't affect them much
@bunny_murphy
Жыл бұрын
I can relate to your entire situation! Sending love and light your way. I want to try Ketamine infusions when I have the money , I don’t know what else to do.
@donnawiseman3686
Жыл бұрын
@@bunny_murphy i don't think ketamine is available in Australia
@donnawiseman3686
Жыл бұрын
@@bunny_murphy thankyou 🙂
@brntmoondoll4jaw
Жыл бұрын
Drinking occasionally (even binge drinking occasionally) doesn't have a huge impact on psych meds in my experience. Occasionally I have felt depressed after a night of drinking for like a day or two. If you drink a lot, though, the medication(s) may not be as effective as they would be without a lot of alcohol
@user497-w4f
Жыл бұрын
Hello from HON Kong. Thanks Dr Marks for your effort & education on mental illness. Really appreciate it. Been struggling w MADD for 4 years and no med helped me, switched about 9/10 SSRI SSNI so far and heavy insomnia (ambien & midazolam not working & sleepwalk after that) . just started TMS as my last resort. Hope it helps. Wanted to give up meds , been on and off suicidal. mental ill really sucks. Happy to find your channel though
@SynasterHax
Жыл бұрын
Thanks for this video. I also have hypothyroidism, but that's being treated, so I guess that helps. Unfortunately, I also take three medications that you mentioned that could potentially make my depression worse. I'll be sure to look into alternatives for those, and maybe even add turmeric or saffron supplements to all of the supplements that I already take. 😅
@DrTraceyMarks
Жыл бұрын
Thanks for reminding me. I need to go take my supplements. They can really add up 😊
@simonjimenez4663
11 ай бұрын
@@DrTraceyMarkshow are you doing beautiful 😍
@burytheseoldghostsd0wn_
11 күн бұрын
I've been in therapy and on meds since I was 15. I'm 35 now. I grew up with some special needs, mostly just mild learning disabilities. Over the years I have been on every medication under the sun and never got anywhere. Everyone treated me as just another really depressed and anxious person. A few years ago I found out that my whole life I'm actually a higher functioning autistic, which explains why I've never gotten much relief through medication. If you've been struggling with this all of your life I encourage you to find a psychologist and get tested. Unfortunately many psychs and therapist aren't trained to spot autism. I even went for TMS treatment recently, the full 6 weeks and only saw a very slight benefit from it. For many autistics with treatment resistant depression it comes down to more life skills and training and figuring out how to cope with the bad depression days than actually getting rid of it completely, since autism itself can mimic many of the signs of depression emotionally wise.
@napoleonfeanor
11 ай бұрын
How does tramadol cause depression? I read that it actually helps against it if taken as XR for chronic pain (such as it was in my case) because some metabolites make it also an SNRI among others. Maybe other more recent studies show different things? I took high doses of it for years until regulations were changed and I was no longer allowed to take it in such doses and was switched to oxycodon 15mg XR all 12h. This is just anecdotal but I felt better under tramadol (less inactive).
@leedavis6343
Жыл бұрын
Ok, I know full well that this comment is very off topic, but it's the very first thing I noticed in the video. And that is the outfit. It is BEAUTIFUL!! It just looks so professional, yet ready for summertime! I just have to know, where did you get it because I want to get one just like it for my sister!
@DrTraceyMarks
Жыл бұрын
Gosh thank you Lee! I’m fine with off topic compliments. The dress is Michael Kors. I got it a few years ago at the Kors outlet here in the Atlanta area.
@thelostone6981
Жыл бұрын
Insightful as always. I personally went through 5-6 different treatments that never worked…until one night 15 years ago, I found myself in a psych unit because of some self destructive behavior. A lot changed, including a bi-polar 1 diagnosis,and I was put on a medication that helped me sleep at night. That was the first time my life changed! Because I was sleeping at night, I could make more rational decisions and I was able better control my emotional needs. There still was a lot of depression and feelings of failure, but I better understood things. (It helped that I had a strong support system in my wife and take great joy in being around my dogs) The second time it changed, which I guarantee NO ONE recommends, is that I…um….well, I will leave you guessing because it’s a condition many people suffer from and it destroys lives. But for me, it help me relax and become much more philosophical. It helped me understand my upbringing better, human nature better, and I became super intrigued by astrophysics, geology, and other sciences. It was a very enlightening period. So it help me, but I don’t recommend it because I’ve had a hard time kicking the habit in order to get my health better on track. The third time was 2 years ago when I tried some of my wife’s ADHD medication. I believe, and my psychiatrist agrees,that I personally, am not bi-polar, but have some attention deficits…plus a bad upbringing. So despite the national If you’ve made it this far, be good to yourself and find the right, board-certified professionals if you don’t have them. It may take a few tries and people, but I know they are out there.
@TheAllKnighter53-t8o
27 күн бұрын
7 months of deep depression, depersonalisation and 100% Insomnia. On a cocktail of Mertazapine, Quitiapine, Melatonin and Zopiclone to knock me out at night. Still getting knocked out but less and less sleep. Depression is so deep.
@brntmoondoll4jaw
Жыл бұрын
Sitting here dissolving a ketamine lozenge as I watch this video lol. I have been extremely treatment resistant for over 6 years. Lexapro helps slightly but not enough, and above 30mg makes depression worse. Lamictal also helps but isn't enough and causes extreme emotional side effects above 100mg. The only two things that have drastically improved my depression symptoms are Caplyta (super new medication) and ketamine. I didn't even consider the fact that side effects don't technically render a drug a treatment failure. I've dealt with a ton of side effects over the years but I've also tried a lot of medications that simply don't work.
@codexamalgam5939
Жыл бұрын
Every SSRI I tried works, but they all had awful side effects except prozac (which did also make it difficult to sleep for the first few weeks).
@nicknagy3343
10 ай бұрын
How can negative side effects not be considered a medication failure. Isn’t the whole point of medication to help relieve the negative symptoms from any given disease. If the drug causes more harm than good to a person. Then it has failed in its intended purpose to help. When she said that I laughed at the craziness of it.
@ladybaabaa3294
Жыл бұрын
I've tried 8 antidepressants since early 2013 and none have really helped. All but 2 have made me feel significantly worse. I find that Alprazolam, and to a lesser extent Clonazepam, actually are the most effective meds for my type of anhedonic depression. My depression is directly caused by anxiety and they help that, so thus my depression greatly improves. Interesting that Lamotrigine can cause depression. I read it was used to lift depression in Bipolar patients rather than dampen mania. Tramadol also. I actually find this the most effective "antidepressant" of all the ones I've tried, due to its impact on opioid receptors, it's Serotonergic properties and its pain relief (I have chronic headaches).
@cat.cryptid
Ай бұрын
I added Abilify to my depression treatment and it changed my life ... for about two months. I really thought I found something that would finally work. It's so frustrating and discouraging to keep trying things and see mixed results.
@Athoo121
5 ай бұрын
Sir. 10 yr ago i hav started panic atack ancity . Im taking nexito 10 mg its cured. Then stop medicine.1 yr late come back panic attack. But that time nexito didn't work. Then im try lot of ssri.not good results.Then last 3 yr back i got depresion symtoms too.Then im till now on venlafaxine and mirtaz and benzo.last 10 month depresion 50% ok Anxity till going. Now i hav a wory about Whne my medicin stop working. Wat r the precociousness im taking for good work for my antidepressants for didn't stop work. Long time. Medication cost is high. Is generic medicine is good for me or bad? Pls reply? I have some times hard brain zapz wat can i do
@AngelinaX23
2 ай бұрын
I have tried nearly every psych med known to man, from lithium to cymbalta, and all I get are side effects. This week I just started a parasite cleanse. I've heard that parasites can cause a variety of issues. I've done cleanses in the past, including fasting, and had some success. I'm 76 and I haven't done a gut cleanse for over 10 years. I have nothing to lose but a few bucks for the pills and possibly this intractable depression.
@woolfy02
11 ай бұрын
I have TRD but, noticed after I had done the 36 treatments of TMS, the medications helped a little better. My problem is, they don't work for long. At this point, I have nothing else really to try. My current meds don't really work or therapy. No place near me available to try ketamine treatments (Or the money to cover the costs). ECT is only available for me if I was inpatient. At times, I just wanted to admit myself and, beg them that they would give me it. Depression is pure hell...plain and simple. I feel so lost and have no hope for any part of my future. I just exist. No plans no goals no..nothing. I just wake up and do the same routine over and over and over again. Honestly, I'd agree to have my legs removed and live in a wheelchair, if it meant that I wouldn't have to deal with this day in, day out. TRD literally sucks all the life out of you. I'm sure a lot of people here, can relate exactly as how I'm feeling. At my next psychiatrist appointment, I'm going to tell him I'm done with meds for good. I just realized that some people just can't be made better and, I don't want to stress him out more over trying to find a fix for me. I just have to accept it for what it is. I want other people / patients to be able to see him since, they might get better. That amazingly makes me feel somewhat good knowing that, another person might have a chance at a better life.
@marylamb6063
11 ай бұрын
My severe depression was caused by five foods I was eating and nothing else. I suspect that your diet was never, ever discussed. A Chinese doctor helped me with that. A Colombian doctor told me that antibiotics would be needed to kill bad gut bacteria, and he was right. I can eat these foods now after having taken three courses of antibiotics. I suspect that none of your doctors ever mentioned the fact that many cases of "treatment-resistant depression" are due to bad gut bacteria interacting with proteins in foods. I was where you were, and I had to go outside the American crappy system and go to non-American doctors.
@woolfy02
11 ай бұрын
@@marylamb6063 No, I can't say any doctor has ever mentioned my diet being a cause. I do believe that it can for sure, have a big impact on it. I have tried to go down that path of trying different natural medicines / vitamins and stuff. I've have tried different vitamin blood panel things and, nothing has worked unfortunately. (Testing for pyroluria / zinc / copper ratios) I do know that I have a lot of stomach issues related to eating me for some reason. I want to have more testing done but, I just don't have the money for it. (I'm sure no one really does right now). Hopefully, I will be able to do more testing like you mentioned. Idk what's wrong with me. I really don't. I haven't focused on healing the gut so, maybe that's something I need to work on. The whole standard medical system/industry seems to just want us to be sick in a way. No clue why a full vitamin panel, isn't something that could be added for standard blood tests. Anyways, I happy that you are doing a lot better with it. It's always nice to hear that someone has overcome it. It does give me hope that things will get better eventually.
@woolfy02
10 ай бұрын
@Bayko117 That made absolutely no sense, to what I asked.
@povorot_netuda
17 күн бұрын
One of the reason of threatment resistant depression is having enough money for antidepressants but not enough to gain independence from others.
@santonen359
Жыл бұрын
I am taking both sertraline and montelukast for my asthma. I have learned from med school that montelukast have a black box label of greater risk of having suicide and having vivid dreams
@gyeung9410
Жыл бұрын
I was prescribed singulair one time years ago I didn’t know about the black box warning. The doctors and pharmacist didn’t even mention it. It was only until a gym goer pointed it out when she saw the pills in my purse
@JeffreyWilliams-dr7qe
5 ай бұрын
Dr please throw us a bone and cover treatment resistant bipolar disorder. Afterall depression being the B team to the Varsity Bipolar 1. Thanks!
@mranoraks5860
Жыл бұрын
Ur mind is so strong it will make you take your own life.
@rachna0367
Жыл бұрын
depression returns after finishing antidepressants..I hope some effective treatment comes that cures heaviness and pressure in my head ..10 years of anxiety, chronic depression, ocd, bdd etc .
@nerdbamarich2063
Жыл бұрын
What have you been on?
@davidcatlett4052
Жыл бұрын
Good luck to you. I hope you find an effective treatment.
@rachna0367
Жыл бұрын
@@davidcatlett4052 thanks
@rachna0367
Жыл бұрын
@@nerdbamarich2063 clonazepam on n off ,.I didn't take other combination of keds due to fear of liver damage due to medicine
@nerdbamarich2063
Жыл бұрын
@@rachna0367 oh okay I totally understand. I deal with OCD and rumination and my anxiety got worse after having covid last year. I'm now on effexor.
@mbuyelo7131
Жыл бұрын
Childhood trauma. Psilocybin cured 7 years of my anguish by basically forcing me to confront all my issues. My medications made me comply with my situation and didn't allow me to process my emotions.
@joysamuel6318
Жыл бұрын
Have tried mushroom and other psychedelic products. Yeah I have a sure plug that I do order from
@joysamuel6318
Жыл бұрын
With the help of Dwayne_myco, who prescribes some mushroom required for depression, I was able to over come depression and anxiety. Yeah he is a mycologist who deals in mushroom and psychedelic products.
@GabyAR7575
Жыл бұрын
Great video Dr. I'm not improving from my depression, so my Dr asked me some test including TSH, T3, T4 and glycemia. I've never been so tired and discourage. I just want to sleep all day when typically I have insomnia. Also y take lamotrigin but never caused me a problem.
@marylamb6063
11 ай бұрын
Antibiotics cured me of severe, suicidal depression. I was labeled "treatment-resistant" but was helped by a Chinese doctor and a Colombian doctor. Non-American doctors see depression as a whole-body issue.
@meganl3859
18 күн бұрын
Definitely not the French…
@ViirinSoftworks
Жыл бұрын
I'm pretty sure my issue is too rare to make a video on, but I'll still bring it up because you're cool like that. I was in a mental institute in 1988 (8 years old) and was given some sort of medication, which I don't know. I did talk to the place a few years ago to get the records, but they didn't have them anymore. Anyway, whatever med they gave me gave me a severe allergic reaction, and I almost died. Now, I won't even listen to a psychologist that suggests medication because of that situation. Do you have any interest in doing a video about people who need psych meds, but because of an allergic reaction to an unknown med of the same nature, they won't do it no matter how much it might benefit them because of what damage it might cause?
@obgfoster
Жыл бұрын
So if you were allergic to strawberries you wouldn't eat any food at all?
@ViirinSoftworks
Жыл бұрын
@@obgfoster I'll rewrite your question. "So if you were allergic to a glowing fluid that made you go into such a severe allergic reaction that you would have died in less than an hour after touching it, and you had no way to know what that glowing fluid was, you wouldn't touch any strange glowing substances?" Correct. I would not touch anything similar to it.
@codexamalgam5939
Жыл бұрын
Your reaction is absolutely understandable! I would tell this to your doctor, I'm sure that they can do allergy testing for the ingredients in the things they might prescribe.
@ViirinSoftworks
Жыл бұрын
@@codexamalgam5939 I have. There is testing for normal allergies, but not medications, surprisingly.
@KayefX
Жыл бұрын
Wait a minute... Are you telling me that drugs are not the answer to my problems?? NO. WAY!
@shawnaford5540
Жыл бұрын
As Dr Marks stated so frustrating and in my experience disabling. TRD did get a lot of relief when removed from SSRI. Seems it causes anhedonia. So for years in a depression ‘coma’. Then finally got a full review and diagnosed as neurodivergent ASD and ME/CFS. So the fatigue is ME not always depression. Now my depression is PDD. I lost years just because I was being treated for the wrong condition(s). I as shocked I am autistic but so much makes sense. So lesson learned having side effects, nightmares poor sleep and ‘nothing’ seems to work try to get a full life review and try to get individual treatment. And TRD is not the same as non-compliant. Even this term is suspect as when I was labeled non-compliant it when I said the exercise program I was prescribed made my depression worse. Did not trigger a look see into post exertional malaise. PEM.
@mauriciojr.4428
Жыл бұрын
What is your treatment now?
@nickdavis3550
6 ай бұрын
My DR. Did a swab to eliminate what antidepressants won't work on me Have you heard of this?
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