Your brain is super fragile. So how come it doesn’t get totally wrecked by infections or bacteria? Well, you’ve got this nifty protection called the blood-brain barrier! To help guide us through your brain’s awesome defense, we brought on Catie Profaci, a graduate student at UCSD and a blood-brain barrier expert! Find out more about your brain’s specialized endothelial cells and what happens when the BBB malfunctions.
Catie’s writing: neuwritesd.org/author/cprofaci/
Catie on Twitter: / cprofaci
Pics of Catie in Lab: / badass-hard-at-18833391
In this episode of Neuro Transmissions, Alie and Catie discuss the blood-brain barrier, which is comprised of endothelial cells that protect the brain from potentially dangerous molecules circulating in the blood stream. The video explains the structure of the blood-brain barrier and covers the BBB’s tight junctions. Alie also gets to talk about her favorite brain cell, astrocytes, and how astrocytic end feet also help maintain the blood-brain barrier. Finally, we cover what can happen when the blood-brain barrier breaks down. We hope you enjoy the video and learn a little more about this often-misunderstood part of the brain!
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