Summary: There are 1000000000000000000 possible reasons and we don’t know which. Great.
@willnitschke
11 ай бұрын
Still preferable to some expert telling you exactly why and then talking bullshit. 😂
@monnoo8221
11 ай бұрын
all 3 pats of that proposition are wrong
@gotem370
Ай бұрын
More like you need to take 5k worth of blood tests and pay a concierge service doctor $1500 to tell you what is wrong with you because general practice doctors won’t do it
@GuitarPlayingTV
11 ай бұрын
Damn I definitely has this problem too. Oxalates are a huge problem for me which I know for a fact also because I have increased need for b6. Glycine messes me up as well because it increases endogneous oxalate production as well. For some reason thiamine and magnesium also sometimes increase oxalate burden for me, I think in that case its like they dump oxalates and then calcium aint sufficient to bind it up. 50% reduction in brain power is crazy. That's exactly how I feel. Also, interesting that that study you pulled up said oxalates reduce cholesterol synthesis. Knowing my struggle with oxalate, this might be the first time I found an explanation for my chronically low cholesterol level of about 80.
@monnoo8221
11 ай бұрын
This is rather " " == empty. If you do not measure the oxalate in your blood and urine which you certainly are not, you can not make any of your statement
@GuitarPlayingTV
10 ай бұрын
@@monnoo8221 I mean I know for a fact I have an oxalate problem. The calcium thing was just hypothesis of course trying to think my way through it but increased oxalate is fact for me
@benjaminbritt7862
Ай бұрын
If someone has iron overload or oxalate overload then vitamin C supplementation will make it worse
@Arnthorg
11 ай бұрын
I've read that vitamin c converts to oxalate on the shelf even, if that's correct you might be dosing yourself with straight oxalates when you take vit c supps
@DesertDog8989
11 ай бұрын
👀
@tanyasydney2235
11 ай бұрын
Yes, correct. Keep Vit. C intake to less than 250mg.
@1truthseeking8
11 ай бұрын
@@tanyasydney2235if thatnid true, then taking ANY/ALL vitamin C should be accompanied by Calcium &/or Dairy (raw & A2) - as calcium binds to oxalates while in the digestive tract and prevents their absorption. ...of course this also poses the likelihood of variability in the amount of calcium remaining available for absorption.
@chrismasterjohn
11 ай бұрын
I've never seen that.
@chrismasterjohn
11 ай бұрын
Calcium is to prevent absorption of oxalate in the intestines.
@petrichor100
4 ай бұрын
I did a metabolix with Genova and also in the process of getting my whole genome sequenced. I have been on the waitlist since last year. Can't wait to work with you.
@monnoo8221
11 ай бұрын
a study measuring the effects of oxalates is made on rats. Thats ok for checking out the effect of oxalate intake, which can reach several grams per day for a vegan. That can be reduced by feeding on dairy together with veggies. Yet, in case of vit C we need to consider that rats do make their own vitamin c, in an amount that would equal 7g per day for a human. A human who is not ingesting vit c , or only very little, and no oxalates from food, obviously the mechanisms to get rid of oxalate, or to keep it out from the cell, are not trained. The conclusion that high amounts of oxalates intake or build up from vit C would invariably intoxicating the TCA in the mitochondria of any tissue, is far fetched. Of course, oxalate is an inhibitor of the TCA, an effective one, in order to control it. But the ingested oxalate must flow into the cell and reach the inside of the mitochondria. I think that is excluded for physiological concentrations. I take 1000---1500 mg almost every day since 30 y, and my fibrous and mental condition is far better than that of my age cohort (N=1), without kidney stones. It is extremely important to keep the collagen flexible, from red blood cells to vessels to tendons. And here VC helps. I appreciate your attempt to be complete. But actually it serves as a foundation for inverted placebo, when reading the comments below. I also would abstain from sources where the respective author does not have a proper perspective on metabolism...
@rdance3
4 ай бұрын
I believe that I have accurately diagnosed myself with low C "again". This time, it was because I decided to take a ketone breath test after my last meal of the day. I've never taken ketone measurements after eating because I assumed that they would be Zero since I have such trouble getting into ketosis. Boy was I wrong! About 30 minutes after eating two beef patties, my ketones were 4 times higher than normal! Here's the kicker....that was my last meal of the day. The next morning, I took another ketone breath test and I had ZERO. Hypothesis: The beef added the necessary Carnitine to get fat into the cells.
@DeeElle2
11 ай бұрын
I think it'd be more interesting if test subjects were tested for yeast overgrowth before and after the test. What's their antibiotics history (which may increase yeast overgrowth and degrade oxalobacter formigenes, which helps digest oxalate)? Do they live in mold or had they lived in mold at all? Mold can increase oxalate sensitivity. I don't have muscle pain, but vein pain (chronic venous insufficiency/think heart disease) - I specifically get a pain in my left leg when over-ingesting vitamin C (buffered powder used during a vitamin C challenge to poop, and daily lemon/oranges/blueberries-ouch), however, I also get similar pain in the same place when I ingested lactulose for a SIBO breath test (positive, methane), so suspect sugars are an issue also (carb metabolism off due to oxalate? idk all the pathways). I did a stool test and found I have some Klebsiella p. and Desulfovibrio. Klebs increases with lemon ... huh. Desulfovibrio is swamp water related apparently, and can be tied to Parkinson's (I DID swim in lakes and streams as a kid, idk, I haven't delved on that one). Joint pain much? YES: severe osteoarthritis > weeks of shortened gait, then sat down and couldn't get up. Had to walk at 90 degree angle for a time. EXTREME pain and it's like it hit all at once. (~2yrs after gallbladder removal ie had IV antibiotics during hospital stay after a history of antibiotic use for xyz) > then add in all the lemon, oranges, blueberries. Part of my treatment after the osteoarthritis dx was IV vitamin C bc I was thinking infection (no g6pd snp here)-ugh. Point is I'm working on building back up my lacto and bifido strains to see if it helps. Sally K. Norton's book doesn't delve much into yeast overgrowth which I think deserves a chapter, but I did ask her about it, and she said minding reduction of oxalate will serve me well in that regard. So far, so good, slow as it is. fwiw!
@monnoo8221
11 ай бұрын
berberine helps against yeast, in TCM since many thousands of years. SIBO, and bad bacteria: combi approach with fermented food, no sugar, and leafs = salad from tropaeolum majus (medical plant of the year 2003, if i remember properly) Fermentation feeding can be supported by taking Lactobacillus reuterii. regarding lemons: i suggest not only to take the juice, but also the pulp AND the shell ...just remove the outermost layer if not bio/truly organic . The oils in there are extremely beneficial. further support for the guts: tea tree oil: 2 drops in 5 ml MCT for several days. Regarding oxalate : see above. It is a nobrainer, and largely exaggerated imho.
@ering8309
11 ай бұрын
Omg this happenes to me!! Been trying to code crack exactly why so thank you for this!
@YourLifeRedefined
11 ай бұрын
Super helpful. Can’t wait to work with you. On the waitlist.
@lindadunn8787
11 ай бұрын
Thank you. Liked & subscribed.
@sharonw2008
11 ай бұрын
This happened to both my daughter and I, we had to stop it.
@cubalkan
10 ай бұрын
Linus Pauling took 15 g for decades ..stayed active in his 90s ...I have been taking 6 g every day and feeling great..😂
@user08157
11 ай бұрын
High dose vitamin C made me terribly anxious.
@stefanallard3084
16 күн бұрын
Or did you combine it with caffine As it makes stims stronger due to dopamin upregulation
@viktortikka8544
11 ай бұрын
what about most vitamin c is made from corn sprayed with glyphosate so you get glyphosate every time you take it?
@michaelransom5841
11 ай бұрын
vitamin c and coper deficiency is only true when administered together... this also causes liver and renal toxicity... co-administration of vitamin c and copper or iron should be avoided. Yes it increases iron absorption, but it also creates ROS, making vitamin c a net pro oxidant.
@frankrocca9142
11 ай бұрын
but if you don't have these symptoms, how much good vitamin C should you take to be healthy? All this information you give must be somewhat pragmatic. Vitamin C can also become pro-oxidant. so what dose to take is what everyone wants to know to make sense
@chrismasterjohn
11 ай бұрын
I'll make a video on this.
@LastDays7
11 ай бұрын
Ascorbate calcium? Calcium binds the oxalates.
@chrismasterjohn
11 ай бұрын
In the intestines, but the oxalate would be made inside the body from the C.
@lemercenairedelespace4199
11 ай бұрын
I feel terrible when i eat nuts , fruits , beans and leafy greens , is it the cause of oxalates ?
@debbicornell1
11 ай бұрын
All these foods are on medium/high ox level
@Larsonaut
11 ай бұрын
Maybe
@MixtrisUFOimages
11 ай бұрын
I heard eating calcium or potassium based foods with your meal binds to oxalates. Yoghurt is a good source. Or research ways to remove oxalates or reduce intake like cooking vegetables etc
@tanyasydney2235
11 ай бұрын
@@MixtrisUFOimages Eating some dairy with high ox foods helps, but it's best to simply avoid those foods to begin with.
@grmalinda6251
11 ай бұрын
Grew up putting vinigar on canned spinach. No one had these issues.
@johan2380
11 ай бұрын
Chris, is there anything else we need to do to starting working with you to optimize my health? I signed up for the wait list on website for the gene/DNA optimization
@chrismasterjohn
11 ай бұрын
We will get to you when we can!
@n-ish
11 ай бұрын
Also, maybe excessive vit C can lead to an increment in reductive stress under some circumstances?
@chrismasterjohn
11 ай бұрын
I think it's silly to distinguish between oxidative and reductive stress. Call it all redox stress.
@n-ish
11 ай бұрын
@@chrismasterjohn thanks for reply, Chris!
@n-ish
11 ай бұрын
@@chrismasterjohn Because one always cause another as consequence? Please, clarify.
@Caribe78
19 сағат бұрын
this guy makes me so anxious cause i dont know what to eat or supplement everytime is different
@David-tq5qm
11 ай бұрын
Thank You Dr! Kindly check the work of Dr. Thomas J Levy MD on vitamin C, in his book “Curing the incurable: Vitamin C …” You might change some of your conclusions after reading it.
@1truthseeking8
11 ай бұрын
. @Chris Masterjohn, PhD ... How much can Glycerin used in "gel caps" versus Glycerin used in sublingual supplements play a role in causing side effects? Causing inflammation? Recently personally experienced this "effect" when using a sublingual supplement that contained "vegetable glycerin" .. didn't conmect the dots until i discovered that "Glycerin" is the exact same ingredient in SUPPOSITORIES. took about three weeks before Experiencing for over two months of symptoms like autoimmune full body ..
@chrismasterjohn
11 ай бұрын
I doubt it's something so general as "causing inflammation" but of course it can be a problem for some people, like most things.
@MixtrisUFOimages
11 ай бұрын
Does it matter the source of vit C? either ascorbic acid powder v from food
@wozzlebaby5313
11 ай бұрын
Came here to ask the same thing
@DeeElle2
11 ай бұрын
In my experience, either source is a source of vitamin C and can produce symptoms.
@MixtrisUFOimages
11 ай бұрын
@@DeeElle2 ok. I thought food based vitc is complexed with other stuff which is different from plain ascorbic powder?
@DeeElle2
11 ай бұрын
@@MixtrisUFOimages That may be, but both have "xyz" ... perhaps the ascorbic acid powder is mold derived (aspergillus) so produces oxalate? I'm living in high aspergillus/pencillium and also react to citric acid (mold derived?). I tested high in yeast metabolites on Metabolomix+. Everyone's ability to detox incoming "xyz" will vary. Food ascorbic acid/vitamin C also may have sugars which feed the yeast/mold. As for food-"based" supplement I cannot say my experience.
@MixtrisUFOimages
11 ай бұрын
@@DeeElle2 ok 👍
@TL....
11 ай бұрын
if taking a vitamin c supplement, would it be a good idea to supplement with daily 2mg copper bisglycinate and 30mg sucrosomial zinc ? (apparently vitamin c depletes copper)
@alexanderohanlon8825
11 ай бұрын
No it doesn't, morly robins is completly wrong... Vit c actually is essential for copper uptake in the intestines... Extract from doris lohs peer reviewed published work " In addition to the rapid reduction of iron prior to cellular uptake, ascorbate also facilitates copper reduction by DCtyb. Thus the optimal absorption and utilization of iron and copper by DCytb is dependent on the availability of ascorbate and related proton-electron recycling processes [70]. Inadequate ascorbate in Dyctb can lead to decreased copper absorption. Excess Fe(III) has been shown to inhibit uptake of copper from ceruloplasmin due to the involvement of Dyctb in the absorption process. Excess Fe(III) overwhelms the reduction capacity of Dyctb, leading to reduced absorption of copper [75, 76, 77] ."...
@chrismasterjohn
11 ай бұрын
It's good to take the C away from meals and apart from copper supplements. The rest is overkill.
@chrismasterjohn
11 ай бұрын
Ok, but 500 mg vitamin C with each of three meals decreases serum copper.
@StarHarvestOfficial
11 ай бұрын
They might be using Emergen C which has B6 and could be experiencing B6 toxicity too
@Boyhowdy875
11 ай бұрын
Emergen C also contains L aspartic acid which apparently can act as a neurotoxin.
@savariaxa
11 ай бұрын
I use for almost 4 years whole food Vitamine C from Garden of life brand and that’s something different no side effects 250 mg !
@jirihutecka9020
11 ай бұрын
Chris I know how hypoglycemia feels and I really don't have to measure my blood sugar to confirm this lol.. When I have hypoglycemia in my case mainly from eating high carb/sugar meal with low protein, fat fiber content symptoms start with blurred vision, dizziness, weakness, shaky hands, strong cravings for sweet stuff and sweating... For cases like that I have pure glucose powder(dextrose) and when I ingest around 20g with sip of water within 5 minutes everything is OK. In some cases I didn't have any type of sugar with me and I managed to not collapse, but it was very scary.. I think I have simply low adrenal function so when my insulin spikes a lot after eating some stupid meal adrenals have hard time to respond with adequate cortisol release...
@1truthseeking8
11 ай бұрын
Insulin insensitivity. ... "Broken metabolism" .... There are more technical explanations, but you may want to consider that you are Deficient in digestive stomach acid and pancreatic Digestive enzymes - and suffering the mechanistlic effects of Amino Acid deficiency as well as other malabsorption issues.
@jirihutecka9020
11 ай бұрын
@@1truthseeking8 Doesn't make any sense what you just wrote lol... What has to do stomach acid with hypoglycemia from eating a lot of simple sugars?
@chrismasterjohn
11 ай бұрын
If you measure your blood sugar when you feel hypoglycemic several times and show you are predictably right, then you can say that.
@jirihutecka9020
11 ай бұрын
@@chrismasterjohn Chris lol pls.. I was a bodybuilder for 15 years. I know If I have hypoglycemia or not LOL. This is not rocket science...
@AmandaBuxbaum
11 ай бұрын
Vitamin C increases your endogenous production of oxylates! That would cause all the symptoms
@harmonic3350
11 ай бұрын
Doesnt true "vitamin C" include copper as opposed to ascorbic acid? (semantics)
@alexanderohanlon8825
11 ай бұрын
Vitamin c is ascorbic acid, thats the molecule animals produce from glucose... True vit c is just a con to get you to buy super expensive dehydrated plant matter.
@NishanK-ed3xy
11 ай бұрын
Well I use a natural Vitamin C (amla,rose hips and lemon extract) and it used to work well now it just makes me feel airy and less alert
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